Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic

Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms with...

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Published inTranslational psychiatry Vol. 12; no. 1; pp. 98 - 8
Main Authors Cai, Hong, Bai, Wei, Liu, Huanzhong, Chen, Xu, Qi, Han, Liu, Rui, Cheung, Teris, Su, Zhaohui, Lin, Jingxia, Tang, Yi-lang, Jackson, Todd, Zhang, Qinge, Xiang, Yu-Tao
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 10.03.2022
Nature Publishing Group
Subjects
692/699/476/1414
706/648
Adolescent
Anxiety
Anxiety - epidemiology
Anxiety Disorders - epidemiology
Behavioral Sciences
Biological Psychology
COVID-19
Depression - epidemiology
Emotions
Humans
Medicine
Medicine & Public Health
Neurosciences
Pandemics
Pharmacotherapy
Psychiatry
Teenagers
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Abstract Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms within the depressive-anxiety symptoms network model. Depressive and anxiety symptoms were assessed using the Patient Health Questionire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of depressive and anxiety symptoms was characterized using “Strength” and “Bridge Strength” as centrality indices in the symptom network. Network stability was tested using a case-dropping bootstrap procedure. Finally, a Network Comparison Test (NCT) was conducted to examine whether network characteristics differed on the basis of gender, school grade and residence. Network analysis revealed that nodes PHQ2 (“Sad mood”), GAD6 (“Irritability”), GAD3 (“Worry too much”), and PHQ6 (“Guilty”) were central symptoms in the network model of adolescents. Additionally, bridge symptoms linking anxiety and depressive symptoms in this sample were nodes PHQ6 (“Guilty”), PHQ2 (“Sad mood”), and PHQ9 (“Suicide ideation”). Gender, school grade and residence did not significantly affect the network structure. Central symptoms (e.g., Sad mood, Irritability, Worry too much, and Guilty) and key bridge symptoms (e.g., Guilty, Sad mood, and Suicide ideation) in the depressive and anxiety symptoms network may be useful as potential targets for intervention among adolescents who are at risk for or suffer from depressive and anxiety symptoms.
AbstractList Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms within the depressive-anxiety symptoms network model. Depressive and anxiety symptoms were assessed using the Patient Health Questionire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of depressive and anxiety symptoms was characterized using "Strength" and "Bridge Strength" as centrality indices in the symptom network. Network stability was tested using a case-dropping bootstrap procedure. Finally, a Network Comparison Test (NCT) was conducted to examine whether network characteristics differed on the basis of gender, school grade and residence. Network analysis revealed that nodes PHQ2 ("Sad mood"), GAD6 ("Irritability"), GAD3 ("Worry too much"), and PHQ6 ("Guilty") were central symptoms in the network model of adolescents. Additionally, bridge symptoms linking anxiety and depressive symptoms in this sample were nodes PHQ6 ("Guilty"), PHQ2 ("Sad mood"), and PHQ9 ("Suicide ideation"). Gender, school grade and residence did not significantly affect the network structure. Central symptoms (e.g., Sad mood, Irritability, Worry too much, and Guilty) and key bridge symptoms (e.g., Guilty, Sad mood, and Suicide ideation) in the depressive and anxiety symptoms network may be useful as potential targets for intervention among adolescents who are at risk for or suffer from depressive and anxiety symptoms.Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms within the depressive-anxiety symptoms network model. Depressive and anxiety symptoms were assessed using the Patient Health Questionire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of depressive and anxiety symptoms was characterized using "Strength" and "Bridge Strength" as centrality indices in the symptom network. Network stability was tested using a case-dropping bootstrap procedure. Finally, a Network Comparison Test (NCT) was conducted to examine whether network characteristics differed on the basis of gender, school grade and residence. Network analysis revealed that nodes PHQ2 ("Sad mood"), GAD6 ("Irritability"), GAD3 ("Worry too much"), and PHQ6 ("Guilty") were central symptoms in the network model of adolescents. Additionally, bridge symptoms linking anxiety and depressive symptoms in this sample were nodes PHQ6 ("Guilty"), PHQ2 ("Sad mood"), and PHQ9 ("Suicide ideation"). Gender, school grade and residence did not significantly affect the network structure. Central symptoms (e.g., Sad mood, Irritability, Worry too much, and Guilty) and key bridge symptoms (e.g., Guilty, Sad mood, and Suicide ideation) in the depressive and anxiety symptoms network may be useful as potential targets for intervention among adolescents who are at risk for or suffer from depressive and anxiety symptoms.
Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms within the depressive-anxiety symptoms network model. Depressive and anxiety symptoms were assessed using the Patient Health Questionire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of depressive and anxiety symptoms was characterized using “Strength” and “Bridge Strength” as centrality indices in the symptom network. Network stability was tested using a case-dropping bootstrap procedure. Finally, a Network Comparison Test (NCT) was conducted to examine whether network characteristics differed on the basis of gender, school grade and residence. Network analysis revealed that nodes PHQ2 (“Sad mood”), GAD6 (“Irritability”), GAD3 (“Worry too much”), and PHQ6 (“Guilty”) were central symptoms in the network model of adolescents. Additionally, bridge symptoms linking anxiety and depressive symptoms in this sample were nodes PHQ6 (“Guilty”), PHQ2 (“Sad mood”), and PHQ9 (“Suicide ideation”). Gender, school grade and residence did not significantly affect the network structure. Central symptoms (e.g., Sad mood, Irritability, Worry too much, and Guilty) and key bridge symptoms (e.g., Guilty, Sad mood, and Suicide ideation) in the depressive and anxiety symptoms network may be useful as potential targets for intervention among adolescents who are at risk for or suffer from depressive and anxiety symptoms.
Abstract Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level relationships between depressive and anxiety symptoms using network analysis in an adolescent sample and identified the most central symptoms within the depressive-anxiety symptoms network model. Depressive and anxiety symptoms were assessed using the Patient Health Questionire-9 (PHQ-9) and Generalized Anxiety Disorder Screener (GAD-7), respectively. The structure of depressive and anxiety symptoms was characterized using “Strength” and “Bridge Strength” as centrality indices in the symptom network. Network stability was tested using a case-dropping bootstrap procedure. Finally, a Network Comparison Test (NCT) was conducted to examine whether network characteristics differed on the basis of gender, school grade and residence. Network analysis revealed that nodes PHQ2 (“Sad mood”), GAD6 (“Irritability”), GAD3 (“Worry too much”), and PHQ6 (“Guilty”) were central symptoms in the network model of adolescents. Additionally, bridge symptoms linking anxiety and depressive symptoms in this sample were nodes PHQ6 (“Guilty”), PHQ2 (“Sad mood”), and PHQ9 (“Suicide ideation”). Gender, school grade and residence did not significantly affect the network structure. Central symptoms (e.g., Sad mood, Irritability, Worry too much, and Guilty) and key bridge symptoms (e.g., Guilty, Sad mood, and Suicide ideation) in the depressive and anxiety symptoms network may be useful as potential targets for intervention among adolescents who are at risk for or suffer from depressive and anxiety symptoms.
ArticleNumber 98
Author Jackson, Todd
Qi, Han
Xiang, Yu-Tao
Lin, Jingxia
Chen, Xu
Bai, Wei
Liu, Rui
Liu, Huanzhong
Zhang, Qinge
Cheung, Teris
Su, Zhaohui
Tang, Yi-lang
Cai, Hong
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/35273161$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1001/jamapsychiatry.2015.2079
10.1002/nur.21784
10.31234/osf.io/dv6c9
10.1056/NEJMp048078
10.1176/appi.ajp.2009.08121849
10.1111/appy.12452
10.1017/S003329171200147X
10.1016/S0140-6736(13)61611-6
10.1111/appy.12472
10.1016/j.jad.2017.05.050
10.1016/j.chiabu.2016.08.002
10.1111/j.1469-7610.2006.01682.x
10.1111/appy.12406
10.1002/wps.20630
10.1016/j.bbi.2020.05.061
10.1016/S2215-0366(15)00505-2
10.1017/S0033291716002300
10.1097/01.chi.0000172552.41596.6f
10.1111/jora.12651
10.1093/biomet/asn034
10.1111/appy.12490
10.1016/j.jad.2019.02.062
10.1016/j.socnet.2010.03.006
10.1371/journal.pone.0119895
10.1371/journal.pone.0179891
10.1007/s10826-017-0837-y
10.1016/j.jad.2020.10.016
10.1016/j.jad.2019.11.012
10.3758/s13428-017-0862-1
10.1007/978-3-030-17332-6_22
10.1016/j.ijdrr.2020.101845
10.1038/srep05918
10.1080/02791072.2010.10400698
10.1176/appi.ajp.2016.16070839
10.1001/archinte.166.10.1092
10.1001/jamapsychiatry.2018.0468
10.1007/s10608-018-9981-y
10.1016/j.jad.2015.09.005
10.1016/j.jaac.2018.05.027
10.1176/appi.books.9780890425596
10.1080/13651501.2020.1791345
10.1017/S0033291713002900
10.1176/appi.ajp.2020.20030304
10.3389/fpsyg.2015.00309
10.1046/j.1525-1497.2001.016009606.x
10.1007/s10802-007-9194-4
10.1038/nature16030
10.1037/a0034733
10.1037/abn0000446
10.1111/appy.12272
10.1038/s41398-021-01271-4
10.1371/journal.pone.0090311
10.1001/jamapediatrics.2021.2482
10.1007/s10964-012-9827-y
10.1002/da.23136
10.2196/18576
10.1016/j.biopsycho.2017.09.005
10.1007/s00787-020-01541-4
10.1111/appy.12103
10.1080/15374416.2018.1437735
10.1146/annurev-clinpsy-050212-185608
10.1016/S0378-8733(03)00012-1
10.1016/S2215-0366(16)30348-0
10.1007/s10826-015-0334-0
10.1016/j.jad.2020.03.078
10.3389/fpsyg.2017.01066
10.1016/S0193-953X(02)00107-7
10.32614/CRAN.package.networktools
10.1016/j.schres.2017.02.018
10.1016/j.ecresq.2019.12.011
10.1007/s10964-020-01332-9
10.1037/0022-006X.65.1.161
10.1097/01.chi.0000223313.25536.47
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References EpskampSCramerAOJWaldorpLJSchmittmannVDBorsboomDqgraph: network visualizations of relationships in psychometric dataJ Stat Softw201212012
KroenkeKSpitzerRLWilliamsJBThe PHQ‐9: validity of a brief depression severity measureJ Gen Intern Med200116606131:STN:280:DC%2BD3MrhtVWnsQ%3D%3D11556941149526810.1046/j.1525-1497.2001.016009606.x
FriedEIProblematic assumptions have slowed down depression research: why symptoms, not syndromes are the way forwardFront Psychol2015630925852621436964410.3389/fpsyg.2015.00309
LiXTangXWuHWangMLiLCOVID-19-related stressors and Chinese adolescents’ adjustment: the moderating role of coping and online learning satisfactionFront Psychiatry202112241
CostelloEJEggerHAngoldA10-year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burdenJ Am Acad Child Adolesc Psychiatry200544972861617510210.1097/01.chi.0000172552.41596.6f
CoyneJCSchwenkTLThe relationship of distress to mood disturbance in primary care and psychiatric populationsJ Consult Clin Psychol1997651611:STN:280:DyaK2s3lslSktw%3D%3D910374510.1037/0022-006X.65.1.161
WhitefordHADegenhardtLRehmJBaxterAJFerrariAJErskineHEGlobal burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010Lancet2013382157586.2399328010.1016/S0140-6736(13)61611-6
World Health Organization. The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. World Health Organization; 1992.
VigoDThornicroftGAtunREstimating the true global burden of mental illnessLancet Psychiatry2016317182685133010.1016/S2215-0366(15)00505-2
Marques de MirandaDda Silva AthanasioBSena OliveiraACSimoes-e-SilvaACHow is COVID-19 pandemic impacting mental health of children and adolescents?Int J Disaster Risk Reduct20205110184532929399748117610.1016/j.ijdrr.2020.101845
Nielsen MS, Clausen CE, Hirota T, Kumperscak H, Guerrero A, Kaneko H, et al. A comparison of child and adolescent psychiatry in the Far East, the Middle East, and Southeast Europe. Asia‐Pac Psychiatry 2021:e12490.
R Core Team. R: A language and environment for statistical computing. 2020. https://www.R-project.org/.
BaxterAJScottKVosTWhitefordHGlobal prevalence of anxiety disorders: a systematic review and meta-regressionPsychol Med2013438979101:STN:280:DC%2BC38jovVymtA%3D%3D2278148910.1017/S003329171200147X
HeXYLiCBQianJCuiHSWuWYReliability and validity of a generalized anxiety disorder scale in general hospital outpatients (in Chinese)Shanghai Arch Psychiatry2010222003
KaiserTHerzogPVoderholzerUBrakemeierELUnraveling the comorbidity of depression and anxiety in a large inpatient sample: network analysis to examine bridge symptomsDepression Anxiety20213830717.3346528410.1002/da.23136
Van LoonAWCreemersHEVogelaarSMiersACSaabNWestenbergPMPrepandemic risk factors of COVID‐19‐related concerns in adolescents during the COVID‐19 pandemicJ Res Adolesc2021315314534448296845690310.1111/jora.12651
KleinmanACulture and depressionNew Engl J Med200435195131:CAS:528:DC%2BD2cXnt12nur8%3D1534279910.1056/NEJMp048078
BeardCMillnerAJForgeardMJFriedEIHsuKJTreadwayMNetwork analysis of depression and anxiety symptom relationships in a psychiatric samplePsychol Med201646335969.1:STN:280:DC%2BC2svgtFahsw%3D%3D27623748543008210.1017/S0033291716002300
McElroyEFearonPBelskyJFonagyPPatalayPNetworks of depression and anxiety symptoms across developmentJ Am Acad Child Adolesc Psychiatry20185796473.30522742629012110.1016/j.jaac.2018.05.027
BorsboomDCramerAONetwork analysis: an integrative approach to the structure of psychopathologyAnnu Rev Clin Psychol20139911212353748310.1146/annurev-clinpsy-050212-185608
Estévez LópeEMorenoDJiménezTAggressive behavior in adolescence as a predictor of personal, family, and school adjustment problemsPsicothema2018306673
Wasserman D, Carli V, Iosue M, Javed A, Herrman H. Suicide prevention in childhood and adolescence: a narrative review of current knowledge on risk and protective factors and effectiveness of interventions. Asia‐Pac Psychiatry 2021;13:e12452.
AiTXuQLiXLiDInterparental conflict and Chinese adolescents’ suicide ideation and suicide attempts: the mediating role of peer victimizationJ Child Fam Stud20172635021110.1007/s10826-017-0837-y
RasingSCreemersDHJanssensJMScholteRHDepression and anxiety prevention based on cognitive behavioral therapy for at-risk adolescents: a meta-analytic reviewFront Psychol20178106628701980548759210.3389/fpsyg.2017.01066
Racine N, McArthur BA, Cooke JE, Eirich R, Zhu J, Madigan S, et al. Global prevalence of depressive and anxiety symptoms in children and adolescents during COVID-19: a meta-analysis. JAMA Pediatr. 2021;175:1142–50.
FriedEINesseRMThe impact of individual depressive symptoms on impairment of psychosocial functioningPLoS ONE20149e9031124587318393868610.1371/journal.pone.00903111:CAS:528:DC%2BC2cXhsVGrtr7K
ZhouS-JZhangL-GWangL-LGuoZ-CWangJ-QChenJ-CPrevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19Eur Child Adolesc Psychiatry202029749583236349210.1007/s00787-020-01541-4
MullarkeyMCMarchettiIBeeversCGUsing network analysis to identify central symptoms of adolescent depressionJ Clin Child Adolesc Psychol20194865668.2953308910.1080/15374416.2018.1437735
ParkS-CKimDThe centrality of depression and anxiety symptoms in major depressive disorder determined using a network analysisJ Affect Disord202027119263231269310.1016/j.jad.2020.03.078
ZhangYLLiangWChenZMZhangHMZhangJHWengXQValidity and reliability of Patient Health Questionnaire‐9 and Patient Health Questionnaire‐2 to screen for depression among college students in ChinaAsia‐Pac Psychiatry2013526875.2412385910.1111/appy.12103
CummingsCMCaporinoNEKendallPCComorbidity of anxiety and depression in children and adolescents: 20 years afterPsychol Bull20141408162421915510.1037/a0034733
Jones P. Networktools: Assorted tools for identifying important nodes in network. R package version 120. 2018.
BrotmanMAKircanskiKStringarisAPineDSLeibenluftEIrritability in youths: a translational modelAm J Psychiatry2017174520322810371510.1176/appi.ajp.2016.16070839
Chernick MR. Bootstrap methods: a guide for practitioners and researchers. John Wiley & Sons; 2011.
World health organization. Adolescent mental health. 2021.
Epskamp S. Fried EI Package ‘bootnet’. 2018. https://cran.r-project.org/web/packages/bootnet/index.html.
FoygelRDrtonMExtended Bayesian information criteria for Gaussian graphical modelsAdv Neural Inf Process Syst2010201060412
TangSXiangMCheungTXiangY-TMental health and its correlates among children and adolescents during COVID-19 school closure: the importance of parent-child discussionJ Affect Disord202127935360.1:CAS:528:DC%2BB3cXit1GrsLnO3309904910.1016/j.jad.2020.10.016
ZubrickSRHafekostJJohnsonSESawyerMGPattonGLawrenceDThe continuity and duration of depression and its relationship to non-suicidal self-harm and suicidal ideation and behavior in adolescents 12–17J Affect Disord201722049562859509810.1016/j.jad.2017.05.050
MarchettiIHopelessness: a network analysisCogn Ther Res201943611910.1007/s10608-018-9981-y
KircanskiKWhiteLKTsengW-LWigginsJLFrankHRSequeiraSA latent variable approach to differentiating neural mechanisms of irritability and anxiety in youthJAMA Psychiatry201875631929625429613752310.1001/jamapsychiatry.2018.0468
BringmannLFElmerTEpskampSWhat do centrality measures measure in psychological networks?J Abnorm Psychol20191288923131824510.1037/abn0000446
BoschlooLBekhuisEWeitzESReijndersMDeRubeisRJDimidjianSThe symptom‐specific efficacy of antidepressant medication vs. cognitive behavioral therapy in the treatment of depression: Results from an individual patient data meta‐analysisWorld Psychiatry2019181839131059603650241610.1002/wps.20630
DavidsonLLGrigorenkoELBoivinMJRapaESteinAA focus on adolescence to reduce neurological, mental health and substance-use disabilityNature2015527S161S6.1:CAS:528:DC%2BC2MXhvVKrur7J2658032210.1038/nature16030
Jane CostelloEErkanliAAngoldAIs there an epidemic of child or adolescent depression?J Child Psychol Psychiatry200647126371.1:STN:280:DC%2BD28jjvVWntA%3D%3D17176381
FeigelmanWGormanBSProspective predictors of premature death: evidence from the National Longitudinal Study of Adolescent HealthJ Psychoactive Drugs201042353612105375810.1080/02791072.2010.10400698
BlackSWPösselPThe combined effects of self-referent information processing and ruminative responses on adolescent depressionJ Youth Adolesc2013421145542305435110.1007/s10964-012-9827-y
SantosHJrFriedEIAsafu‐AdjeiJRuizRJNetwork structure of perinatal depressive symptoms in Latinas: relationship to stress and reproductive biomarkersRes Nurs Health2017402182828220506550330610.1002/nur.21784
ChenXQiHLiuRFengYLiWXiangMDepression, anxiety and associated factors among Chinese adolescents during the COVID-19 outbreak: a comparison of two cross-sectional studiesTransl Psychiatry2021111:CAS:528:DC%2BB3MXls1Kqsbs%3D33654058792161110.1038/s41398-021-01271-4
MagsonNRFreemanJYRapeeRMRichardsonCEOarELFardoulyJRisk and protective factors for prospective changes in adolescent mental health during the COVID-19 pandemicJ Youth Adolesc20215044573310854210.1007/s10964-020-01332-9
van RooijenGIsvoranuAMMeijerCJA symptom network structure of the psychosis spectrumSchizophr Res201718975832823760610.1016/j.schres.2017.02.018
HuBYWuHWinslerAFanXSongZParent migration and rural preschool children’s early academic and social skill trajectories in China: are ‘left-behind’children really left behind?Early Child Res Q20205131728.10.1016/j.ecresq.2019.12.011
LiDLiXWangYBaoZParenting and Chinese adolescent suicidal ideation and suicide attempts: the mediating role of hopelessnessJ Child Fam Stud201625139740710.1007/s10826-015-0334-0
LuoHLieYPrinzenFWSurveillance of COVID-19 in the general population using an online questionnaire: report from 18,161 respondents in ChinaJMIR Public Health Surveill20206e1857632319956718776310.2196/18576
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References_xml – reference: Jane CostelloEErkanliAAngoldAIs there an epidemic of child or adolescent depression?J Child Psychol Psychiatry200647126371.1:STN:280:DC%2BD28jjvVWntA%3D%3D17176381
– reference: LuoHLieYPrinzenFWSurveillance of COVID-19 in the general population using an online questionnaire: report from 18,161 respondents in ChinaJMIR Public Health Surveill20206e1857632319956718776310.2196/18576
– reference: KılınçelŞKılınçelOMuratdağıGAydınAUstaMBFactors affecting the anxiety levels of adolescents in home‐quarantine during COVID‐19 pandemic in TurkeyAsia‐Pac Psychiatry202113e124063278338910.1111/appy.12406
– reference: BaxterAJScottKVosTWhitefordHGlobal prevalence of anxiety disorders: a systematic review and meta-regressionPsychol Med2013438979101:STN:280:DC%2BC38jovVymtA%3D%3D2278148910.1017/S003329171200147X
– reference: FriedEINesseRMZivinKGuilleCSenSDepression is more than the sum score of its parts: individual DSM symptoms have different risk factorsPsychol Med201444206776.1:STN:280:DC%2BC2c3hvFartw%3D%3D2428985210.1017/S0033291713002900
– reference: van BorkuloCBoschlooLBorsboomDPenninxBWWaldorpLJSchoeversRAssociation of symptom network structure with the course of depressionJAMA Psychiatry2015721219262656140010.1001/jamapsychiatry.2015.2079
– reference: LiXTangXWuHWangMLiLCOVID-19-related stressors and Chinese adolescents’ adjustment: the moderating role of coping and online learning satisfactionFront Psychiatry202112241
– reference: FeigelmanWGormanBSProspective predictors of premature death: evidence from the National Longitudinal Study of Adolescent HealthJ Psychoactive Drugs201042353612105375810.1080/02791072.2010.10400698
– reference: BoddenDHDirksenCDBögelsSMSocietal burden of clinically anxious youth referred for treatment: a cost-of-illness studyJ Abnorm Child Psychol20083648797.18214667227745010.1007/s10802-007-9194-4
– reference: World health organization. Adolescent mental health. 2021.
– reference: ChenFZhengDLiuJGongYGuanZLouDDepression and anxiety among adolescents during COVID-19: A cross-sectional studyBrain Behav Immun202088361:CAS:528:DC%2BB3cXhtVOlu7zM32464156724749610.1016/j.bbi.2020.05.061
– reference: JonesPJMaRMcNallyRJBridge centrality: a network approach to understanding comorbidityMultivariate Behav Res201956115
– reference: SpitzerRLKroenkeKWilliamsJBLoweBA brief measure for assessing generalized anxiety disorder: the GAD-7Arch Intern Med2006166109271671717110.1001/archinte.166.10.1092
– reference: OpsahlTAgneessensFSkvoretzJNode centrality in weighted networks: generalizing degree and shortest pathsSoc Netw20103224551.10.1016/j.socnet.2010.03.006
– reference: Epskamp S. Fried EI Package ‘bootnet’. 2018. https://cran.r-project.org/web/packages/bootnet/index.html.
– reference: AiTXuQLiXLiDInterparental conflict and Chinese adolescents’ suicide ideation and suicide attempts: the mediating role of peer victimizationJ Child Fam Stud20172635021110.1007/s10826-017-0837-y
– reference: Racine N, McArthur BA, Cooke JE, Eirich R, Zhu J, Madigan S, et al. Global prevalence of depressive and anxiety symptoms in children and adolescents during COVID-19: a meta-analysis. JAMA Pediatr. 2021;175:1142–50.
– reference: KaiserTHerzogPVoderholzerUBrakemeierELUnraveling the comorbidity of depression and anxiety in a large inpatient sample: network analysis to examine bridge symptomsDepression Anxiety20213830717.3346528410.1002/da.23136
– reference: FavaMRushAJTrivediMHBackground and rationale for the sequenced treatment alternatives to relieve depression (STAR∗ D) studyPsychiatr Clin North Am200326457941277884310.1016/S0193-953X(02)00107-7
– reference: KleinmanACulture and depressionNew Engl J Med200435195131:CAS:528:DC%2BD2cXnt12nur8%3D1534279910.1056/NEJMp048078
– reference: Jones P. Networktools: Assorted tools for identifying important nodes in network. R package version 120. 2018.
– reference: ParkS-CKimDThe centrality of depression and anxiety symptoms in major depressive disorder determined using a network analysisJ Affect Disord202027119263231269310.1016/j.jad.2020.03.078
– reference: VigoDThornicroftGAtunREstimating the true global burden of mental illnessLancet Psychiatry2016317182685133010.1016/S2215-0366(15)00505-2
– reference: EbertDDZarskiA-CChristensenHStikkelbroekYCuijpersPBerkingMInternet and computer-based cognitive behavioral therapy for anxiety and depression in youth: a meta-analysis of randomized controlled outcome trialsPLoS ONE201510e011989525786025436496810.1371/journal.pone.01198951:CAS:528:DC%2BC28XhtFalsb7F
– reference: LimGYTamWWLuYHoCSZhangMWHoRCPrevalence of depression in the community from 30 countries between 1994 and 2014Sci Rep20188110
– reference: FriedEINesseRMThe impact of individual depressive symptoms on impairment of psychosocial functioningPLoS ONE20149e9031124587318393868610.1371/journal.pone.00903111:CAS:528:DC%2BC2cXhsVGrtr7K
– reference: MullarkeyMCMarchettiIBeeversCGUsing network analysis to identify central symptoms of adolescent depressionJ Clin Child Adolesc Psychol20194865668.2953308910.1080/15374416.2018.1437735
– reference: CostelloEJEggerHAngoldA10-year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burdenJ Am Acad Child Adolesc Psychiatry200544972861617510210.1097/01.chi.0000172552.41596.6f
– reference: NieX-DWangQWangM-NZhaoSLiuLZhuY-LAnxiety and depression and its correlates in patients with coronavirus disease 2019 in WuhanInt J Psychiatry Clin Pract202025109143266269210.1080/13651501.2020.17913451:CAS:528:DC%2BB3cXhsFShs7vK
– reference: FriedEIProblematic assumptions have slowed down depression research: why symptoms, not syndromes are the way forwardFront Psychol2015630925852621436964410.3389/fpsyg.2015.00309
– reference: ZhouS-JZhangL-GWangL-LGuoZ-CWangJ-QChenJ-CPrevalence and socio-demographic correlates of psychological health problems in Chinese adolescents during the outbreak of COVID-19Eur Child Adolesc Psychiatry202029749583236349210.1007/s00787-020-01541-4
– reference: EpskampSCramerAOJWaldorpLJSchmittmannVDBorsboomDqgraph: network visualizations of relationships in psychometric dataJ Stat Softw201212012
– reference: ZhouJLiuLXuePYangXTangXMental health response to the COVID-19 outbreak in ChinaAm J Psychiatry202017757453237554010.1176/appi.ajp.2020.20030304
– reference: EpskampSBorsboomDFriedEIEstimating psychological networks and their accuracy: a tutorial paperBehav Res Methods2018501952122834207110.3758/s13428-017-0862-1
– reference: World Health Organization. Ensuring mental health an well-being in an adolescent’s formative years can foster a better transition from childhood to adulthood. 2021.
– reference: ZubrickSRHafekostJJohnsonSESawyerMGPattonGLawrenceDThe continuity and duration of depression and its relationship to non-suicidal self-harm and suicidal ideation and behavior in adolescents 12–17J Affect Disord201722049562859509810.1016/j.jad.2017.05.050
– reference: Riecher-RösslerASex and gender differences in mental disordersLancet Psychiatry20174892785639710.1016/S2215-0366(16)30348-0
– reference: Osborn TL, Campbell S, Ndetei D, Weisz J. Network analysis reveals central symptoms of adolescent depression and anxiety in sub-Saharan Africa. 2020.
– reference: HeXYLiCBQianJCuiHSWuWYReliability and validity of a generalized anxiety disorder scale in general hospital outpatients (in Chinese)Shanghai Arch Psychiatry2010222003
– reference: MarchettiIHopelessness: a network analysisCogn Ther Res201943611910.1007/s10608-018-9981-y
– reference: BlackSWPösselPThe combined effects of self-referent information processing and ruminative responses on adolescent depressionJ Youth Adolesc2013421145542305435110.1007/s10964-012-9827-y
– reference: KroenkeKSpitzerRLWilliamsJBThe PHQ‐9: validity of a brief depression severity measureJ Gen Intern Med200116606131:STN:280:DC%2BD3MrhtVWnsQ%3D%3D11556941149526810.1046/j.1525-1497.2001.016009606.x
– reference: van RooijenGIsvoranuAMMeijerCJA symptom network structure of the psychosis spectrumSchizophr Res201718975832823760610.1016/j.schres.2017.02.018
– reference: Estévez LópeEMorenoDJiménezTAggressive behavior in adolescence as a predictor of personal, family, and school adjustment problemsPsicothema2018306673
– reference: McElroyEFearonPBelskyJFonagyPPatalayPNetworks of depression and anxiety symptoms across developmentJ Am Acad Child Adolesc Psychiatry20185796473.30522742629012110.1016/j.jaac.2018.05.027
– reference: ChenXQiHLiuRFengYLiWXiangMDepression, anxiety and associated factors among Chinese adolescents during the COVID-19 outbreak: a comparison of two cross-sectional studiesTransl Psychiatry2021111:CAS:528:DC%2BB3MXls1Kqsbs%3D33654058792161110.1038/s41398-021-01271-4
– reference: American Psychiatric Association. Diagnostic and statistical manual of mental disorders (Edition, Fifth). Am Psychiatric Assoc. 2013;21:160–8.
– reference: EpskampSKruisJMarsmanMEstimating psychopathological networks: be careful what you wish forPLoS ONE201712e017989128644856548247510.1371/journal.pone.01798911:CAS:528:DC%2BC1cXot1Wi
– reference: FoygelRDrtonMExtended Bayesian information criteria for Gaussian graphical modelsAdv Neural Inf Process Syst2010201060412
– reference: Marques de MirandaDda Silva AthanasioBSena OliveiraACSimoes-e-SilvaACHow is COVID-19 pandemic impacting mental health of children and adolescents?Int J Disaster Risk Reduct20205110184532929399748117610.1016/j.ijdrr.2020.101845
– reference: KircanskiKWhiteLKTsengW-LWigginsJLFrankHRSequeiraSA latent variable approach to differentiating neural mechanisms of irritability and anxiety in youthJAMA Psychiatry201875631929625429613752310.1001/jamapsychiatry.2018.0468
– reference: LiDLiXWangYBaoZParenting and Chinese adolescent suicidal ideation and suicide attempts: the mediating role of hopelessnessJ Child Fam Stud201625139740710.1007/s10826-015-0334-0
– reference: Wasserman D, Carli V, Iosue M, Javed A, Herrman H. Suicide prevention in childhood and adolescence: a narrative review of current knowledge on risk and protective factors and effectiveness of interventions. Asia‐Pac Psychiatry 2021;13:e12452.
– reference: WhitefordHADegenhardtLRehmJBaxterAJFerrariAJErskineHEGlobal burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010Lancet2013382157586.2399328010.1016/S0140-6736(13)61611-6
– reference: BarberRFDrtonMHigh-dimensional Ising model selection with Bayesian information criteriaElectron J Stat20159567607.
– reference: BeardCMillnerAJForgeardMJFriedEIHsuKJTreadwayMNetwork analysis of depression and anxiety symptom relationships in a psychiatric samplePsychol Med201646335969.1:STN:280:DC%2BC2svgtFahsw%3D%3D27623748543008210.1017/S0033291716002300
– reference: R Core Team. R: A language and environment for statistical computing. 2020. https://www.R-project.org/.
– reference: DaiQChuR-XAnxiety, happiness and self-esteem of western Chinese left-behind childrenChild Abus Negl20188640313.10.1016/j.chiabu.2016.08.002
– reference: ZhangYLLiangWChenZMZhangHMZhangJHWengXQValidity and reliability of Patient Health Questionnaire‐9 and Patient Health Questionnaire‐2 to screen for depression among college students in ChinaAsia‐Pac Psychiatry2013526875.2412385910.1111/appy.12103
– reference: JeonGSChoiKChoSIGender differences in exposure and vulnerability to psychosocial and behavioral factors of suicide attempt among Korean adolescentsAsia‐Pac Psychiatry20179e1227210.1111/appy.12272
– reference: BringmannLFElmerTEpskampSWhat do centrality measures measure in psychological networks?J Abnorm Psychol20191288923131824510.1037/abn0000446
– reference: BrotmanMAKircanskiKStringarisAPineDSLeibenluftEIrritability in youths: a translational modelAm J Psychiatry2017174520322810371510.1176/appi.ajp.2016.16070839
– reference: CoyneJCSchwenkTLThe relationship of distress to mood disturbance in primary care and psychiatric populationsJ Consult Clin Psychol1997651611:STN:280:DyaK2s3lslSktw%3D%3D910374510.1037/0022-006X.65.1.161
– reference: VijayakumarLRaySFernandesTNPathareSA descriptive mapping review of suicide in vulnerable populations in low and middle countriesAsia‐Pac Psychiatry202113e124723381799310.1111/appy.12472
– reference: World Health Organization. The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. World Health Organization; 1992.
– reference: FriedEIEpskampSNesseRMTuerlinckxFBorsboomDWhat are’good’depression symptoms? Comparing the centrality of DSM and non-DSM symptoms of depression in a network analysisJ Affect Disord201618931420.2645818410.1016/j.jad.2015.09.005
– reference: BorsboomDCramerAONetwork analysis: an integrative approach to the structure of psychopathologyAnnu Rev Clin Psychol20139911212353748310.1146/annurev-clinpsy-050212-185608
– reference: Van LoonAWCreemersHEVogelaarSMiersACSaabNWestenbergPMPrepandemic risk factors of COVID‐19‐related concerns in adolescents during the COVID‐19 pandemicJ Res Adolesc2021315314534448296845690310.1111/jora.12651
– reference: Nielsen MS, Clausen CE, Hirota T, Kumperscak H, Guerrero A, Kaneko H, et al. A comparison of child and adolescent psychiatry in the Far East, the Middle East, and Southeast Europe. Asia‐Pac Psychiatry 2021:e12490.
– reference: Chernick MR. Bootstrap methods: a guide for practitioners and researchers. John Wiley & Sons; 2011.
– reference: GarabilesMRLaoCKXiongYHallBJExploring comorbidity between anxiety and depression among migrant Filipino domestic workers: a network approachJ Affect Disord201925085933083628410.1016/j.jad.2019.02.062
– reference: StringarisACohenPPineDSLeibenluftEAdult outcomes of youth irritability: a 20-year prospective community-based studyAm J Psychiatry200916610485419570932279188410.1176/appi.ajp.2009.08121849
– reference: RasingSCreemersDHJanssensJMScholteRHDepression and anxiety prevention based on cognitive behavioral therapy for at-risk adolescents: a meta-analytic reviewFront Psychol20178106628701980548759210.3389/fpsyg.2017.01066
– reference: CostenbaderEValenteTWThe stability of centrality measures when networks are sampledSoc Netw20032528330710.1016/S0378-8733(03)00012-1
– reference: ChenJChenZExtended Bayesian information criteria for model selection with large model spacesBiometrika20089575971.10.1093/biomet/asn034
– reference: SantosHJrFriedEIAsafu‐AdjeiJRuizRJNetwork structure of perinatal depressive symptoms in Latinas: relationship to stress and reproductive biomarkersRes Nurs Health2017402182828220506550330610.1002/nur.21784
– reference: Dainer-BestJTrujilloLTSchnyerDMBeeversCGSustained engagement of attention is associated with increased negative self-referent processing in major depressive disorderBiol Psychol20171292314128893596567352910.1016/j.biopsycho.2017.09.005
– reference: GeorgiadesKLewinsohnPMMonroeSMSeeleyJRMajor depressive disorder in adolescence: the role of subthreshold symptomsJ Am Acad Child Adolesc Psychiatry20064593644.1686503610.1097/01.chi.0000223313.25536.47
– reference: HardsEEllisJFiskJReynoldsSNegative view of the self and symptoms of depression in adolescentsJ Affect Disord202026214383173345810.1016/j.jad.2019.11.012
– reference: Van BorkuloCDBorsboomDEpskampSBlankenTFBoschlooLSchoeversRAA new method for constructing networks from binary dataSci Rep2014425082149411819610.1038/srep059181:CAS:528:DC%2BC2MXksVWntb4%3D
– reference: BoschlooLBekhuisEWeitzESReijndersMDeRubeisRJDimidjianSThe symptom‐specific efficacy of antidepressant medication vs. cognitive behavioral therapy in the treatment of depression: Results from an individual patient data meta‐analysisWorld Psychiatry2019181839131059603650241610.1002/wps.20630
– reference: TangSXiangMCheungTXiangY-TMental health and its correlates among children and adolescents during COVID-19 school closure: the importance of parent-child discussionJ Affect Disord202127935360.1:CAS:528:DC%2BB3cXit1GrsLnO3309904910.1016/j.jad.2020.10.016
– reference: MagsonNRFreemanJYRapeeRMRichardsonCEOarELFardoulyJRisk and protective factors for prospective changes in adolescent mental health during the COVID-19 pandemicJ Youth Adolesc20215044573310854210.1007/s10964-020-01332-9
– reference: Yang Y, Wang Q. Culture in emotional development. Handbook of emotional development: Springer; 2019. p. 569-93.
– reference: HuBYWuHWinslerAFanXSongZParent migration and rural preschool children’s early academic and social skill trajectories in China: are ‘left-behind’children really left behind?Early Child Res Q20205131728.10.1016/j.ecresq.2019.12.011
– reference: CummingsCMCaporinoNEKendallPCComorbidity of anxiety and depression in children and adolescents: 20 years afterPsychol Bull20141408162421915510.1037/a0034733
– reference: DavidsonLLGrigorenkoELBoivinMJRapaESteinAA focus on adolescence to reduce neurological, mental health and substance-use disabilityNature2015527S161S6.1:CAS:528:DC%2BC2MXhvVKrur7J2658032210.1038/nature16030
– volume: 72
  start-page: 1219
  year: 2015
  ident: 1838_CR53
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2015.2079
– volume: 40
  start-page: 218
  year: 2017
  ident: 1838_CR87
  publication-title: Res Nurs Health
  doi: 10.1002/nur.21784
– ident: 1838_CR27
  doi: 10.31234/osf.io/dv6c9
– volume: 351
  start-page: 951
  year: 2004
  ident: 1838_CR28
  publication-title: New Engl J Med
  doi: 10.1056/NEJMp048078
– volume: 8
  start-page: 1
  year: 2018
  ident: 1838_CR30
  publication-title: Sci Rep
– volume: 166
  start-page: 1048
  year: 2009
  ident: 1838_CR71
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.2009.08121849
– ident: 1838_CR82
  doi: 10.1111/appy.12452
– volume: 43
  start-page: 897
  year: 2013
  ident: 1838_CR29
  publication-title: Psychol Med
  doi: 10.1017/S003329171200147X
– volume: 382
  start-page: 1575
  year: 2013
  ident: 1838_CR11
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)61611-6
– volume: 13
  start-page: e12472
  year: 2021
  ident: 1838_CR16
  publication-title: Asia‐Pac Psychiatry
  doi: 10.1111/appy.12472
– volume: 220
  start-page: 49
  year: 2017
  ident: 1838_CR13
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2017.05.050
– volume: 86
  start-page: 403
  year: 2018
  ident: 1838_CR62
  publication-title: Child Abus Negl
  doi: 10.1016/j.chiabu.2016.08.002
– volume: 47
  start-page: 1263
  year: 2006
  ident: 1838_CR4
  publication-title: J Child Psychol Psychiatry
  doi: 10.1111/j.1469-7610.2006.01682.x
– volume: 13
  start-page: e12406
  year: 2021
  ident: 1838_CR66
  publication-title: Asia‐Pac Psychiatry
  doi: 10.1111/appy.12406
– volume: 18
  start-page: 183
  year: 2019
  ident: 1838_CR86
  publication-title: World Psychiatry
  doi: 10.1002/wps.20630
– volume: 88
  start-page: 36
  year: 2020
  ident: 1838_CR9
  publication-title: Brain Behav Immun
  doi: 10.1016/j.bbi.2020.05.061
– volume: 9
  start-page: 567
  year: 2015
  ident: 1838_CR41
  publication-title: Electron J Stat
– volume: 3
  start-page: 171
  year: 2016
  ident: 1838_CR12
  publication-title: Lancet Psychiatry
  doi: 10.1016/S2215-0366(15)00505-2
– volume: 46
  start-page: 3359
  year: 2016
  ident: 1838_CR24
  publication-title: Psychol Med
  doi: 10.1017/S0033291716002300
– ident: 1838_CR49
– volume: 44
  start-page: 972
  year: 2005
  ident: 1838_CR3
  publication-title: J Am Acad Child Adolesc Psychiatry
  doi: 10.1097/01.chi.0000172552.41596.6f
– volume: 31
  start-page: 531
  year: 2021
  ident: 1838_CR70
  publication-title: J Res Adolesc
  doi: 10.1111/jora.12651
– ident: 1838_CR2
– volume: 95
  start-page: 759
  year: 2008
  ident: 1838_CR45
  publication-title: Biometrika
  doi: 10.1093/biomet/asn034
– ident: 1838_CR5
  doi: 10.1111/appy.12490
– volume: 250
  start-page: 85
  year: 2019
  ident: 1838_CR54
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2019.02.062
– ident: 1838_CR58
– volume: 32
  start-page: 245
  year: 2010
  ident: 1838_CR47
  publication-title: Soc Netw
  doi: 10.1016/j.socnet.2010.03.006
– volume: 10
  start-page: e0119895
  year: 2015
  ident: 1838_CR84
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0119895
– volume: 12
  start-page: e0179891
  year: 2017
  ident: 1838_CR21
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0179891
– volume: 26
  start-page: 3502
  year: 2017
  ident: 1838_CR79
  publication-title: J Child Fam Stud
  doi: 10.1007/s10826-017-0837-y
– volume: 279
  start-page: 353
  year: 2021
  ident: 1838_CR8
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2020.10.016
– volume: 262
  start-page: 143
  year: 2020
  ident: 1838_CR75
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2019.11.012
– volume: 12
  start-page: 241
  year: 2021
  ident: 1838_CR69
  publication-title: Front Psychiatry
– volume: 50
  start-page: 195
  year: 2018
  ident: 1838_CR43
  publication-title: Behav Res Methods
  doi: 10.3758/s13428-017-0862-1
– ident: 1838_CR78
  doi: 10.1007/978-3-030-17332-6_22
– volume: 51
  start-page: 101845
  year: 2020
  ident: 1838_CR64
  publication-title: Int J Disaster Risk Reduct
  doi: 10.1016/j.ijdrr.2020.101845
– ident: 1838_CR51
– volume: 56
  start-page: 1
  year: 2019
  ident: 1838_CR22
  publication-title: Multivariate Behav Res
– volume: 4
  year: 2014
  ident: 1838_CR20
  publication-title: Sci Rep
  doi: 10.1038/srep05918
– volume: 42
  start-page: 353
  year: 2010
  ident: 1838_CR15
  publication-title: J Psychoactive Drugs
  doi: 10.1080/02791072.2010.10400698
– volume: 174
  start-page: 520
  year: 2017
  ident: 1838_CR73
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.2016.16070839
– volume: 166
  start-page: 1092
  year: 2006
  ident: 1838_CR35
  publication-title: Arch Intern Med
  doi: 10.1001/archinte.166.10.1092
– volume: 75
  start-page: 631
  year: 2018
  ident: 1838_CR72
  publication-title: JAMA Psychiatry
  doi: 10.1001/jamapsychiatry.2018.0468
– volume: 43
  start-page: 611
  year: 2019
  ident: 1838_CR38
  publication-title: Cogn Ther Res
  doi: 10.1007/s10608-018-9981-y
– volume: 189
  start-page: 314
  year: 2016
  ident: 1838_CR23
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2015.09.005
– ident: 1838_CR37
– volume: 57
  start-page: 964
  year: 2018
  ident: 1838_CR25
  publication-title: J Am Acad Child Adolesc Psychiatry
  doi: 10.1016/j.jaac.2018.05.027
– ident: 1838_CR57
  doi: 10.1176/appi.books.9780890425596
– volume: 2010
  start-page: 604
  year: 2010
  ident: 1838_CR44
  publication-title: Adv Neural Inf Process Syst
– volume: 25
  start-page: 109
  year: 2020
  ident: 1838_CR68
  publication-title: Int J Psychiatry Clin Pract
  doi: 10.1080/13651501.2020.1791345
– volume: 44
  start-page: 2067
  year: 2014
  ident: 1838_CR18
  publication-title: Psychol Med
  doi: 10.1017/S0033291713002900
– volume: 177
  start-page: 574
  year: 2020
  ident: 1838_CR32
  publication-title: Am J Psychiatry
  doi: 10.1176/appi.ajp.2020.20030304
– volume: 6
  start-page: 309
  year: 2015
  ident: 1838_CR40
  publication-title: Front Psychol
  doi: 10.3389/fpsyg.2015.00309
– volume: 16
  start-page: 606
  year: 2001
  ident: 1838_CR34
  publication-title: J Gen Intern Med
  doi: 10.1046/j.1525-1497.2001.016009606.x
– volume: 36
  start-page: 487
  year: 2008
  ident: 1838_CR6
  publication-title: J Abnorm Child Psychol
  doi: 10.1007/s10802-007-9194-4
– volume: 527
  start-page: S161
  year: 2015
  ident: 1838_CR14
  publication-title: Nature
  doi: 10.1038/nature16030
– volume: 30
  start-page: 66
  year: 2018
  ident: 1838_CR67
  publication-title: Psicothema
– volume: 140
  start-page: 816
  year: 2014
  ident: 1838_CR7
  publication-title: Psychol Bull
  doi: 10.1037/a0034733
– volume: 128
  start-page: 892
  year: 2019
  ident: 1838_CR48
  publication-title: J Abnorm Psychol
  doi: 10.1037/abn0000446
– volume: 9
  start-page: e12272
  year: 2017
  ident: 1838_CR81
  publication-title: Asia‐Pac Psychiatry
  doi: 10.1111/appy.12272
– volume: 11
  year: 2021
  ident: 1838_CR10
  publication-title: Transl Psychiatry
  doi: 10.1038/s41398-021-01271-4
– volume: 9
  start-page: e90311
  year: 2014
  ident: 1838_CR17
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0090311
– ident: 1838_CR52
  doi: 10.1001/jamapediatrics.2021.2482
– volume: 42
  start-page: 1145
  year: 2013
  ident: 1838_CR76
  publication-title: J Youth Adolesc
  doi: 10.1007/s10964-012-9827-y
– volume: 38
  start-page: 307
  year: 2021
  ident: 1838_CR56
  publication-title: Depression Anxiety
  doi: 10.1002/da.23136
– volume: 6
  start-page: e18576
  year: 2020
  ident: 1838_CR31
  publication-title: JMIR Public Health Surveill
  doi: 10.2196/18576
– volume: 129
  start-page: 231
  year: 2017
  ident: 1838_CR74
  publication-title: Biol Psychol
  doi: 10.1016/j.biopsycho.2017.09.005
– volume: 29
  start-page: 749
  year: 2020
  ident: 1838_CR65
  publication-title: Eur Child Adolesc Psychiatry
  doi: 10.1007/s00787-020-01541-4
– volume: 1
  start-page: 2012
  year: 2012
  ident: 1838_CR42
  publication-title: J Stat Softw
– volume: 5
  start-page: 268
  year: 2013
  ident: 1838_CR33
  publication-title: Asia‐Pac Psychiatry
  doi: 10.1111/appy.12103
– volume: 48
  start-page: 656
  year: 2019
  ident: 1838_CR26
  publication-title: J Clin Child Adolesc Psychol
  doi: 10.1080/15374416.2018.1437735
– volume: 9
  start-page: 91
  year: 2013
  ident: 1838_CR19
  publication-title: Annu Rev Clin Psychol
  doi: 10.1146/annurev-clinpsy-050212-185608
– volume: 25
  start-page: 283
  year: 2003
  ident: 1838_CR50
  publication-title: Soc Netw
  doi: 10.1016/S0378-8733(03)00012-1
– volume: 4
  start-page: 8
  year: 2017
  ident: 1838_CR83
  publication-title: Lancet Psychiatry
  doi: 10.1016/S2215-0366(16)30348-0
– volume: 25
  start-page: 1397
  year: 2016
  ident: 1838_CR80
  publication-title: J Child Fam Stud
  doi: 10.1007/s10826-015-0334-0
– volume: 271
  start-page: 19
  year: 2020
  ident: 1838_CR55
  publication-title: J Affect Disord
  doi: 10.1016/j.jad.2020.03.078
– volume: 8
  start-page: 1066
  year: 2017
  ident: 1838_CR85
  publication-title: Front Psychol
  doi: 10.3389/fpsyg.2017.01066
– volume: 26
  start-page: 457
  year: 2003
  ident: 1838_CR77
  publication-title: Psychiatr Clin North Am
  doi: 10.1016/S0193-953X(02)00107-7
– ident: 1838_CR39
  doi: 10.32614/CRAN.package.networktools
– volume: 189
  start-page: 75
  year: 2017
  ident: 1838_CR46
  publication-title: Schizophr Res
  doi: 10.1016/j.schres.2017.02.018
– volume: 51
  start-page: 317
  year: 2020
  ident: 1838_CR61
  publication-title: Early Child Res Q
  doi: 10.1016/j.ecresq.2019.12.011
– volume: 22
  start-page: 200
  year: 2010
  ident: 1838_CR36
  publication-title: Shanghai Arch Psychiatry
– volume: 50
  start-page: 44
  year: 2021
  ident: 1838_CR63
  publication-title: J Youth Adolesc
  doi: 10.1007/s10964-020-01332-9
– volume: 65
  start-page: 161
  year: 1997
  ident: 1838_CR59
  publication-title: J Consult Clin Psychol
  doi: 10.1037/0022-006X.65.1.161
– ident: 1838_CR1
– volume: 45
  start-page: 936
  year: 2006
  ident: 1838_CR60
  publication-title: J Am Acad Child Adolesc Psychiatry
  doi: 10.1097/01.chi.0000223313.25536.47
SSID ssj0000548171
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Snippet Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine item-level...
Abstract Network analysis is an effective approach for examining complex relationships between psychiatric symptoms. This study was designed to examine...
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SubjectTerms 692/699/476/1414
706/648
Adolescent
Anxiety
Anxiety - epidemiology
Anxiety Disorders - epidemiology
Behavioral Sciences
Biological Psychology
COVID-19
Depression - epidemiology
Emotions
Humans
Medicine
Medicine & Public Health
Neurosciences
Pandemics
Pharmacotherapy
Psychiatry
Teenagers
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Title Network analysis of depressive and anxiety symptoms in adolescents during the later stage of the COVID-19 pandemic
URI https://link.springer.com/article/10.1038/s41398-022-01838-9
https://www.ncbi.nlm.nih.gov/pubmed/35273161
https://www.proquest.com/docview/2637813000
https://www.proquest.com/docview/2638727031
https://pubmed.ncbi.nlm.nih.gov/PMC8907388
https://doaj.org/article/d31ac83c60184d47a63edeaa84d916bd
Volume 12
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