Adipocyte-derived extracellular vesicles increase insulin secretion through transport of insulinotropic protein cargo - Kulaj, Konxhe; Harger, Alexandra; Bauer, Michaela; Caliskan, Özüm S.; Gupta, Tilak Kumar; Chiang, Dapi Menglin; Milbank, Edward; Reber, Josefine; Karlas, Angelos; Kotzbeck, Petra; Sailer, David N.; Volta, Francesco; et al. (Nature communications, 2023)
Keywords: 13; 13/95; 631/443/319/1642/2815; 631/80/304; 64; 64/60; 82/58; Adipocytes; Adipocytes - metabolism; Adipose tissue; Animals; Beta cells; Body fat; Cargo; Extracellular vesicles; Extracellular Vesicles - metabolism; G protein-coupled receptors; Glucose; Glucose - metabolism; Glucose tolerance; Humanities and Social Sciences; Insulin; Insulin - metabolism; Insulin resistance; Insulin Secretion; Insulin-Secreting Cells - metabolism; Islets of Langerhans - metabolism; Mice; multidisciplinary; Nanoparticles; Obesity - metabolism; Pancreas; Phosphorylation; Protein kinase A; Protein transport; Proteins; Proteomics; Science; Science (multidisciplinary); Secretion; Vesicles