Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse - Ohnishi, Naomi; Yuasa, Hitomi; Tanaka, Shinya; Sawa, Hirofumi; Miura, Motohiro; Matsui, Atsushi; Higashi, Hideaki; Musashi, Manabu; Iwabuchi, Kazuya; Suzuki, Misao; Yamada, Gen; Azuma, Takeshi; et al. (Proceedings of the National Academy of Sciences - PNAS, 2008)
Keywords: Adenocarcinoma; Animals; Antigens, Bacterial - genetics; Antigens, Bacterial - metabolism; Bacteria; Bacterial proteins; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biological Sciences; Bone marrow cells; carcinogenesis; Cell Transformation, Neoplastic - genetics; Cell Transformation, Neoplastic - metabolism; Cell Transformation, Neoplastic - pathology; Epithelial cells; Gastrointestinal Neoplasms - genetics; Gastrointestinal Neoplasms - metabolism; Gastrointestinal Neoplasms - pathology; Gene expression; Gene Expression Regulation, Neoplastic; Helicobacter pylori; Helicobacter pylori - genetics; Helicobacter pylori - metabolism; Helicobacter pylori - pathogenicity; Hematologic Neoplasms - genetics; Hematologic Neoplasms - metabolism; Hematologic Neoplasms - pathology; humans; hyperplasia; Hypersensitivity; Infections; Kinases; Leukocytes; Lymphoma; Mice; Mice, Transgenic; Mutation; oncogene proteins; Phosphorylation; phosphotransferases (kinases); Phosphotyrosine - metabolism; polyps (pathological conditions); Rodents; small intestine; Stomach; Transgenic animals; Tumors; type IV secretion system; tyrosine