FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion - Shao, Wenjun; Li, Jiawei; Piao, Qianling; Yao, Xinlei; Li, Mingyue; Wang, Shuyue; Song, Zhenbo; Sun, Ying; Zheng, Lihua; Wang, Guannan; Liu, Lei; Yu, Chunlei; et al. (Cell death & disease, 2023)
Keywords: 101/28; 13/106; 13/31; 13/51; 45/29; 59/5; 631/67/1347; 631/80/84/2027; 64/60; 82/80; 96/95; Antibodies; Biochemistry; Biomarkers; Biomedical and Life Sciences; Breast cancer; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Cell Biology; Cell Culture; Cell Line, Tumor; Cell migration; Cell Movement; Cell Proliferation; Cytology; Cytoskeleton; Degradation; Female; Focal Adhesions - metabolism; Gene Expression Regulation, Neoplastic; Humans; Immunology; Life Sciences; Medical prognosis; Metastases; Metastasis; Molecular modelling; Proteasomes; Therapeutic targets; Tumor suppressor genes; Tumor Suppressor Proteins - metabolism; Tumors; Ubiquitin; Ubiquitin - metabolism; Ubiquitin-protein ligase; Ubiquitination; Vimentin; Vimentin - metabolism; Xenografts