Investigation of the transcriptomic response in Atlantic salmon (Salmo salar) gill exposed to Paramoeba perurans during early onset of disease

• Published in: Scientific reports Vol. 11; no. 1; p. 20682
• Main Authors: Talbot, Anita, Gargan, Laura, Moran, Grainne, Prudent, Louis, O’Connor, Ian, Mirimin, Luca, Carlsson, Jens, MacCarthy, Eugene
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 19.10.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/337; 631/337/2019; 692/420/254; Amebiasis - genetics; Amebiasis - parasitology; Amoebida - pathogenicity; Animals; Complement activation; Fish diseases; Fish Diseases - genetics; Fish Diseases - parasitology; Gene expression; Genomes; Gills - parasitology; Humanities and Social Sciences; Immune response; Immunosurveillance; Interferon; Interleukins; multidisciplinary; Paramoeba perurans; Parasites; Protozoa; Real-Time Polymerase Chain Reaction - methods; Ribonucleic acid; RNA; Salmo salar; Salmo salar - genetics; Salmo salar - parasitology; Salmon; Science; Science (multidisciplinary); Sequence Analysis, RNA - methods; Signal transduction; Transcriptome - genetics; Transcriptomics; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Tumors

Amoebic Gill Disease (AGD), caused by the protozoan extracellular parasite Paramoeba perurans ( P. perurans ) is a disease affecting Atlantic salmon ( Salmo salar ). This study investigated the gill transcriptomic profile of pre-clinical AGD using RNA-sequencing (RNA-seq) technology. RNA-seq librari...