A Klotho-derived peptide protects against kidney fibrosis by targeting TGF-β signaling - Yuan, Qian; Ren, Qian; Li, Li; Tan, Huishi; Lu, Meizhi; Tian, Yuan; Huang, Lu; Zhao, Boxin; Fu, Haiyan; Hou, Fan Fan; Zhou, Lili; Liu, Youhua (Nature communications, 2022)
Keywords: 13; 13/106; 13/95; 14; 14/19; 14/34; 38; 59; 59/5; 631/154; 631/61/2298; 64; 692/4022/1585; Aging; Amino Acid Sequence; Animal models; Animals; Cell Line; Disease Models, Animal; Fibrosis; Humanities and Social Sciences; Humans; Inflammation - pathology; Intravenous administration; Kidney - injuries; Kidney - metabolism; Kidney - pathology; Kidney - physiopathology; Kidney diseases; Kidney Diseases - complications; Kidney Diseases - pathology; Kidneys; Kinases; Klotho protein; Klotho Proteins - chemistry; Male; Mice; Mice, Inbred BALB C; multidisciplinary; Pathogenesis; Peptides; Peptides - chemistry; Peptides - pharmacology; Phosphorylation - drug effects; Protective Agents - pharmacology; Protein Binding; Protein kinase; Proteins; Rats; Receptors, Transforming Growth Factor beta - metabolism; Reperfusion Injury - complications; Reperfusion Injury - pathology; Reperfusion Injury - physiopathology; Science; Science (multidisciplinary); Signal Transduction; Signaling; Smad Proteins - metabolism; Smad2 protein; Transforming Growth Factor beta - metabolism; Transforming growth factor-b; Ureteral Obstruction - complications; Ureteral Obstruction - pathology