Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells

Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roIFNT) indu...

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Published inScientific reports Vol. 9; no. 1; pp. 14682 - 11
Main Authors Basavaraja, Raghavendra, Madusanka, Senasige Thilina, Drum, Jessica N., Shrestha, Ketan, Farberov, Svetlana, Wiltbank, Milo C., Sartori, Roberto, Meidan, Rina
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 11.10.2019
Nature Publishing Group
Nature Portfolio
Subjects
13
13/1
13/106
13/2
13/31
38
38/77
38/90
631/80/82/23
692/163
82
Animals
Apoptosis
Apoptosis - genetics
Bcl-x protein
Caspase
Caspase-3
Cattle
Cell death
Cell survival
Cell Survival - genetics
Cell viability
Corpus luteum
Corpus Luteum - growth & development
Corpus Luteum - metabolism
Domestic animals
Endometrium - growth & development
Endometrium - metabolism
Female
Fibroblast growth factor 2
Gene Expression Regulation - genetics
Granulosa cells
Granulosa Cells - metabolism
Humanities and Social Sciences
Interferon
Interferon Type I - genetics
Kinases
Luteal Cells - metabolism
Mcl-1 protein
multidisciplinary
Phosphorylation
Pregnancy
Pregnancy Proteins - genetics
Proteins
Science
Science (multidisciplinary)
Sheep - genetics
Sheep - growth & development
Stat1 protein
Thrombospondin
XIAP protein
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Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roIFNT) induced the IFN-stimulated genes (ISGs; MX2 , ISG15 , and OAS1Y ). IFNT induced a rapid and transient (15–45 min) phosphorylation of STAT1, while total STAT1 protein was higher only after 24 h. IFNT treatment elevated viable LGCs numbers and decreased dead/apoptotic cell counts. Consistent with these effects on cell viability, IFNT upregulated cell survival proteins (MCL1, BCL-xL, and XIAP) and reduced the levels of gamma-H2AX, cleaved caspase-3, and thrombospondin-2 (THBS2) implicated in apoptosis. Notably, IFNT reversed the actions of THBS1 on cell viability, XIAP, and cleaved caspase-3. Furthermore, roIFNT stimulated proangiogenic genes, including FGF2 , PDGFB , and PDGFAR . Corroborating the in vitro observations, CL collected from day 18 pregnant cows comprised higher ISGs together with elevated FGF2, PDGFB , and XIAP , compared with CL derived from day 18 cyclic cows. This study reveals that IFNT activates diverse pathways in LGCs, promoting survival and blood vessel stabilization while suppressing cell death signals. These mechanisms might contribute to CL maintenance during early pregnancy.
AbstractList Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roIFNT) induced the IFN-stimulated genes (ISGs; MX2, ISG15, and OAS1Y). IFNT induced a rapid and transient (15–45 min) phosphorylation of STAT1, while total STAT1 protein was higher only after 24 h. IFNT treatment elevated viable LGCs numbers and decreased dead/apoptotic cell counts. Consistent with these effects on cell viability, IFNT upregulated cell survival proteins (MCL1, BCL-xL, and XIAP) and reduced the levels of gamma-H2AX, cleaved caspase-3, and thrombospondin-2 (THBS2) implicated in apoptosis. Notably, IFNT reversed the actions of THBS1 on cell viability, XIAP, and cleaved caspase-3. Furthermore, roIFNT stimulated proangiogenic genes, including FGF2, PDGFB, and PDGFAR. Corroborating the in vitro observations, CL collected from day 18 pregnant cows comprised higher ISGs together with elevated FGF2, PDGFB, and XIAP, compared with CL derived from day 18 cyclic cows. This study reveals that IFNT activates diverse pathways in LGCs, promoting survival and blood vessel stabilization while suppressing cell death signals. These mechanisms might contribute to CL maintenance during early pregnancy.
Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roIFNT) induced the IFN-stimulated genes (ISGs; MX2 , ISG15 , and OAS1Y ). IFNT induced a rapid and transient (15–45 min) phosphorylation of STAT1, while total STAT1 protein was higher only after 24 h. IFNT treatment elevated viable LGCs numbers and decreased dead/apoptotic cell counts. Consistent with these effects on cell viability, IFNT upregulated cell survival proteins (MCL1, BCL-xL, and XIAP) and reduced the levels of gamma-H2AX, cleaved caspase-3, and thrombospondin-2 (THBS2) implicated in apoptosis. Notably, IFNT reversed the actions of THBS1 on cell viability, XIAP, and cleaved caspase-3. Furthermore, roIFNT stimulated proangiogenic genes, including FGF2 , PDGFB , and PDGFAR . Corroborating the in vitro observations, CL collected from day 18 pregnant cows comprised higher ISGs together with elevated FGF2, PDGFB , and XIAP , compared with CL derived from day 18 cyclic cows. This study reveals that IFNT activates diverse pathways in LGCs, promoting survival and blood vessel stabilization while suppressing cell death signals. These mechanisms might contribute to CL maintenance during early pregnancy.
Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roIFNT) induced the IFN-stimulated genes (ISGs; MX2, ISG15, and OAS1Y). IFNT induced a rapid and transient (15-45 min) phosphorylation of STAT1, while total STAT1 protein was higher only after 24 h. IFNT treatment elevated viable LGCs numbers and decreased dead/apoptotic cell counts. Consistent with these effects on cell viability, IFNT upregulated cell survival proteins (MCL1, BCL-xL, and XIAP) and reduced the levels of gamma-H2AX, cleaved caspase-3, and thrombospondin-2 (THBS2) implicated in apoptosis. Notably, IFNT reversed the actions of THBS1 on cell viability, XIAP, and cleaved caspase-3. Furthermore, roIFNT stimulated proangiogenic genes, including FGF2, PDGFB, and PDGFAR. Corroborating the in vitro observations, CL collected from day 18 pregnant cows comprised higher ISGs together with elevated FGF2, PDGFB, and XIAP, compared with CL derived from day 18 cyclic cows. This study reveals that IFNT activates diverse pathways in LGCs, promoting survival and blood vessel stabilization while suppressing cell death signals. These mechanisms might contribute to CL maintenance during early pregnancy.
Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT directly affects the function of luteinized bovine granulosa cells (LGCs), a model for large-luteal cells. Recombinant ovine IFNT (roIFNT) induced the IFN-stimulated genes (ISGs; MX2 , ISG15 , and OAS1Y ). IFNT induced a rapid and transient (15–45 min) phosphorylation of STAT1, while total STAT1 protein was higher only after 24 h. IFNT treatment elevated viable LGCs numbers and decreased dead/apoptotic cell counts. Consistent with these effects on cell viability, IFNT upregulated cell survival proteins (MCL1, BCL-xL, and XIAP) and reduced the levels of gamma-H2AX, cleaved caspase-3, and thrombospondin-2 (THBS2) implicated in apoptosis. Notably, IFNT reversed the actions of THBS1 on cell viability, XIAP, and cleaved caspase-3. Furthermore, roIFNT stimulated proangiogenic genes, including FGF2 , PDGFB , and PDGFAR . Corroborating the in vitro observations, CL collected from day 18 pregnant cows comprised higher ISGs together with elevated FGF2, PDGFB , and XIAP , compared with CL derived from day 18 cyclic cows. This study reveals that IFNT activates diverse pathways in LGCs, promoting survival and blood vessel stabilization while suppressing cell death signals. These mechanisms might contribute to CL maintenance during early pregnancy.
ArticleNumber 14682
Author Basavaraja, Raghavendra
Madusanka, Senasige Thilina
Farberov, Svetlana
Sartori, Roberto
Drum, Jessica N.
Wiltbank, Milo C.
Meidan, Rina
Shrestha, Ketan
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  surname: Drum
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  email: rina.meidan@mail.huji.ac.il
  organization: Department of Animal Sciences, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem
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Cites_doi 10.1210/endo.132.1.8419126
10.1017/S1751731114000585
10.1095/biolreprod.111.095067
10.1095/biolreprod65.4.1038
10.3168/jds.2009-2529
10.1530/REP-11-0277
10.3168/jds.S0022-0302(95)76817-5
10.1186/1477-7827-10-21
10.1074/jbc.M409596200
10.1210/endo.143.4.8726
10.1530/REP-15-0302
10.1262/jrd.2016-056
10.1095/biolreprod.106.052944
10.1101/cshperspect.a009712
10.1152/physiolgenomics.00155.2010
10.1021/pr300144q
10.1530/REP-17-0315
10.1095/biolreprod.114.121020
10.1095/biolreprod.115.132860
10.1053/plac.1998.0381
10.1530/REP-11-0157
10.1152/physiolgenomics.00082.2013
10.1095/biolreprod66.5.1505
10.1095/biolreprod66.2.393
10.1530/REP-09-0030
10.1530/REP-15-0085
10.1007/s10456-018-9644-3
10.2741/s184
10.1262/jrd.17092
10.1152/physrev.1999.79.2.263
10.1038/s41598-017-08805-1
10.1055/s-2001-14839
10.1074/jbc.M109.085605
10.1095/biolreprod.109.079467
10.1158/2159-8290.CD-15-0011
10.1071/RD12182
10.1095/biolreprod.115.135822
10.1152/physrev.2000.80.1.1
10.1210/endo-124-5-2314
10.1530/jrf.0.0850483
10.1038/40901
10.1371/journal.pone.0194456
10.1210/jc.2017-00259
10.1095/biolreprod58.3.849
10.1095/biolreprod29.5.1063
10.1038/nprot.2008.73
10.1095/biolreprod.108.074336
10.1002/mrd.20878
10.1093/biolre/iox167
10.1530/jrf.0.1040001
10.1007/s00441-013-1712-9
10.3390/ph3041241
10.1006/meth.2001.1262
10.3181/00379727-213-44053
10.1095/biolreprod64.2.654
10.1038/35065125
10.1016/j.ygcen.2014.02.008
10.1016/j.theriogenology.2014.01.039
10.1016/j.repbio.2013.12.004
10.1095/biolreprod.112.105684
10.1095/biolreprod43.6.913
10.1093/biolreprod/87.s1.124
10.1210/en.2007-0863
10.1530/REP-17-0290
10.1128/MCB.00581-08
10.1074/jbc.275.13.9390
10.3181/00379727-199-43371A
10.1530/REP-18-0530
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References Binelli (CR20) 2001; 64
Mondal (CR33) 2011; 43
Choi (CR21) 2001; 65
Yamashita (CR63) 2008; 75
Forde (CR2) 2009; 81
Milvae, Hansel (CR28) 1983; 29
Forde (CR4) 2012; 87
Alila, Corradino, Hansel (CR31) 1989; 124
Antoniazzi (CR23) 2013; 88
CR35
Mullen (CR5) 2012; 11
Wu, Wiltbank (CR37) 2002; 66
Bott (CR17) 2010; 82
Nitta (CR48) 2011; 142
Sahmi (CR39) 2014; 200
Juengel, Garverick, Johnson, Youngquist, Smith (CR52) 1993; 132
Rusnati, Urbinati, Bonifacio, Presta, Taraboletti (CR12) 2010; 3
Hirayama (CR22) 2014; 81
Romero (CR46) 2015; 93
Meidan, Milvae, Weiss, Levy, Friedman (CR53) 1999; 54
McCracken, Custer, Lamsa (CR7) 1999; 79
Stewart (CR19) 2002; 66
Solier, Sordet, Kohn, Pommier (CR61) 2009; 29
Laird, Woad, Hunter, Mann, Robinson (CR64) 2013; 25
Hata, Engelman, Faber (CR56) 2015; 5
Baufeld, Vanselow (CR38) 2013; 354
Satterfield, Bazer, Spencer (CR3) 2006; 75
Berisha, Schams, Rodler, Sinowatz, Pfaffl (CR62) 2016; 62
Korzekwa, Okuda, Woclawek-Potocka, Murakami, Skarzynski (CR54) 2006; 52
Deveraux, Takahashi, Salvesen, Reed (CR58) 1997; 388
Barille-Nion, Bah, Vequaud, Juin (CR57) 2012; 32
Farberov, Meidan (CR34) 2016; 94
Adams, Lawler (CR10) 2011; 3
Bazer (CR15) 1992; 199
Bazer, Spencer, Johnson, Burghardt (CR41) 2011; 3
Shirasuna (CR49) 2015; 150
Mamluk, Chen, Greber, Davis, Meidan (CR30) 1998; 58
Colombo (CR11) 2010; 285
Oliveira (CR16) 2008; 149
Schams, Kosmann, Berisha, Amselgruber, Miyamoto (CR40) 2001; 109
Meyer (CR44) 1995; 78
Rogakou, Nieves-Neira, Boon, Pommier, Bonner (CR60) 2000; 275
Livak, Schmittgen (CR72) 2001; 25
Schmittgen, Livak (CR70) 2008; 3
Mann, Lamming (CR42) 1995; 104
Raica, Cimpean (CR68) 2010
Woad (CR65) 2012; 143
Basavaraja (CR25) 2017; 154
Hansen, Sinedino, Spencer (CR13) 2017; 154
Yadav, Lakshmi, Medhamurthy (CR51) 2005; 280
Zalman (CR8) 2012; 86
Srinivasula (CR59) 2001; 410
Woad (CR69) 2009; 138
Farberov, Meidan (CR9) 2014; 91
Kfir (CR71) 2018; 13
Matsuyama, Kojima, Kato, Kimura (CR47) 2012; 10
Lee, Banu, McCracken, Arosh (CR55) 2016; 151
Mohammed, Sontakke, Ioannidis, Duncan, Donadeu (CR36) 2017; 102
Wiltbank (CR6) 2014; 8
He (CR32) 2017; 7
Thatcher (CR45) 1989; 37
Niswender, Juengel, Silva, Rollyson, McIntush (CR1) 2000; 80
Meidan, Girsh, Blum, Aberdam (CR29) 1990; 43
Yang (CR24) 2010; 93
Smith, Meidan (CR26) 2014; 14
O’Shea, Rodgers, D’Occhio (CR27) 1989; 85
Romero (CR18) 2013; 45
Rusnati (CR66) 2019; 22
Carambula (CR50) 2002; 143
Roberts, Ealy, Alexenko, Han, Ezashi (CR14) 1999; 20
Spencer, Ott, Bazer (CR43) 1996; 213
Farberov, Meidan (CR67) 2018; 98
51152_CR35
TD Schmittgen (51152_CR70) 2008; 3
JJ Romero (51152_CR18) 2013; 45
MD Stewart (51152_CR19) 2002; 66
A Nitta (51152_CR48) 2011; 142
JL Juengel (51152_CR52) 1993; 132
WW Thatcher (51152_CR45) 1989; 37
M Rusnati (51152_CR66) 2019; 22
R Meidan (51152_CR53) 1999; 54
GD Niswender (51152_CR1) 2000; 80
M Raica (51152_CR68) 2010
S Farberov (51152_CR34) 2016; 94
MC Satterfield (51152_CR3) 2006; 75
R Meidan (51152_CR29) 1990; 43
G Colombo (51152_CR11) 2010; 285
BT Mohammed (51152_CR36) 2017; 102
FW Bazer (51152_CR15) 1992; 199
EP Rogakou (51152_CR60) 2000; 275
S Farberov (51152_CR67) 2018; 98
M Rusnati (51152_CR12) 2010; 3
A Baufeld (51152_CR38) 2013; 354
R Mamluk (51152_CR30) 1998; 58
MP Mullen (51152_CR5) 2012; 11
B Berisha (51152_CR62) 2016; 62
W He (51152_CR32) 2017; 7
KJ Livak (51152_CR72) 2001; 25
N Forde (51152_CR4) 2012; 87
M Laird (51152_CR64) 2013; 25
S Solier (51152_CR61) 2009; 29
S Farberov (51152_CR9) 2014; 91
S Kfir (51152_CR71) 2018; 13
KJ Woad (51152_CR69) 2009; 138
JD O’Shea (51152_CR27) 1989; 85
Y Choi (51152_CR21) 2001; 65
MC Wiltbank (51152_CR6) 2014; 8
YL Wu (51152_CR37) 2002; 66
JA McCracken (51152_CR7) 1999; 79
TR Hansen (51152_CR13) 2017; 154
K Shirasuna (51152_CR49) 2015; 150
KJ Woad (51152_CR65) 2012; 143
JC Adams (51152_CR10) 2011; 3
AQ Antoniazzi (51152_CR23) 2013; 88
S Matsuyama (51152_CR47) 2012; 10
HW Alila (51152_CR31) 1989; 124
L Yang (51152_CR24) 2010; 93
SF Carambula (51152_CR50) 2002; 143
H Yamashita (51152_CR63) 2008; 75
M Binelli (51152_CR20) 2001; 64
R Basavaraja (51152_CR25) 2017; 154
JJ Romero (51152_CR46) 2015; 93
AN Hata (51152_CR56) 2015; 5
RA Milvae (51152_CR28) 1983; 29
FW Bazer (51152_CR41) 2011; 3
GW Smith (51152_CR26) 2014; 14
M Mondal (51152_CR33) 2011; 43
GE Mann (51152_CR42) 1995; 104
S Barille-Nion (51152_CR57) 2012; 32
Y Zalman (51152_CR8) 2012; 86
F Sahmi (51152_CR39) 2014; 200
RM Roberts (51152_CR14) 1999; 20
N Forde (51152_CR2) 2009; 81
QL Deveraux (51152_CR58) 1997; 388
JF Oliveira (51152_CR16) 2008; 149
H Hirayama (51152_CR22) 2014; 81
SM Srinivasula (51152_CR59) 2001; 410
J Lee (51152_CR55) 2016; 151
VK Yadav (51152_CR51) 2005; 280
RC Bott (51152_CR17) 2010; 82
AJ Korzekwa (51152_CR54) 2006; 52
TE Spencer (51152_CR43) 1996; 213
MD Meyer (51152_CR44) 1995; 78
D Schams (51152_CR40) 2001; 109
References_xml – volume: 132
  start-page: 249
  year: 1993
  end-page: 254
  ident: CR52
  article-title: Apoptosis during luteal regression in cattle
  publication-title: Endocrinology
  doi: 10.1210/endo.132.1.8419126
  contributor:
    fullname: Smith
– volume: 8
  start-page: 70
  issue: Suppl 1
  year: 2014
  end-page: 81
  ident: CR6
  article-title: Physiological and practical effects of progesterone on reproduction in dairy cattle
  publication-title: Animal
  doi: 10.1017/S1751731114000585
  contributor:
    fullname: Wiltbank
– volume: 86
  start-page: 92
  year: 2012
  ident: CR8
  article-title: Regulation of angiogenesis-related prostaglandin f2alpha-induced genes in the bovine corpus luteum
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.111.095067
  contributor:
    fullname: Zalman
– volume: 65
  start-page: 1038
  year: 2001
  end-page: 1049
  ident: CR21
  article-title: Interferon regulatory factor-two restricts expression of interferon-stimulated genes to the endometrial stroma and glandular epithelium of the ovine uterus
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod65.4.1038
  contributor:
    fullname: Choi
– volume: 93
  start-page: 1000
  year: 2010
  end-page: 1011
  ident: CR24
  article-title: Up-regulation of expression of interferon-stimulated gene 15 in the bovine corpus luteum during early pregnancy
  publication-title: J Dairy Sci
  doi: 10.3168/jds.2009-2529
  contributor:
    fullname: Yang
– volume: 143
  start-page: 35
  year: 2012
  end-page: 43
  ident: CR65
  article-title: Fibroblast growth factor 2 is a key determinant of vascular sprouting during bovine luteal angiogenesis
  publication-title: Reproduction
  doi: 10.1530/REP-11-0277
  contributor:
    fullname: Woad
– volume: 78
  start-page: 1921
  year: 1995
  end-page: 1931
  ident: CR44
  article-title: Extension of corpus luteum lifespan and reduction of uterine secretion of prostaglandin F2 alpha of cows in response to recombinant interferon-tau
  publication-title: J Dairy Sci
  doi: 10.3168/jds.S0022-0302(95)76817-5
  contributor:
    fullname: Meyer
– volume: 10
  year: 2012
  ident: CR47
  article-title: Relationship between quantity of IFNT estimated by IFN-stimulated gene expression in peripheral blood mononuclear cells and bovine embryonic mortality after AI or ET
  publication-title: Reprod Biol Endocrinol
  doi: 10.1186/1477-7827-10-21
  contributor:
    fullname: Kimura
– volume: 280
  start-page: 10357
  year: 2005
  end-page: 10367
  ident: CR51
  article-title: Prostaglandin F2alpha-mediated activation of apoptotic signaling cascades in the corpus luteum during apoptosis: involvement of caspase-activated DNase
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M409596200
  contributor:
    fullname: Medhamurthy
– ident: CR35
– volume: 143
  start-page: 1495
  year: 2002
  end-page: 1501
  ident: CR50
  article-title: Caspase-3 is a pivotal mediator of apoptosis during regression of the ovarian corpus luteum
  publication-title: Endocrinology
  doi: 10.1210/endo.143.4.8726
  contributor:
    fullname: Carambula
– start-page: 572
  year: 2010
  end-page: 599
  ident: CR68
  article-title: Platelet-Derived Growth Factor (PDGF)/PDGF Receptors (PDGFR) Axis as Target for Antitumor and Antiangiogenic Therapy
  publication-title: Pharmaceuticals (Basel)
  contributor:
    fullname: Cimpean
– volume: 151
  start-page: 187
  year: 2016
  end-page: 202
  ident: CR55
  article-title: Early pregnancy modulates survival and apoptosis pathways in the corpus luteum in sheep
  publication-title: Reproduction
  doi: 10.1530/REP-15-0302
  contributor:
    fullname: Arosh
– volume: 62
  start-page: 501
  issue: 5
  year: 2016
  end-page: 510
  ident: CR62
  article-title: Expression and localization of members of the thrombospondin family during final follicle maturation and corpus luteum formation and function in the bovine ovary
  publication-title: J Reprod Dev
  doi: 10.1262/jrd.2016-056
  contributor:
    fullname: Pfaffl
– volume: 75
  start-page: 289
  year: 2006
  end-page: 296
  ident: CR3
  article-title: Progesterone regulation of preimplantation conceptus growth and galectin 15 (LGALS15) in the ovine uterus
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.106.052944
  contributor:
    fullname: Spencer
– volume: 3
  start-page: a009712
  year: 2011
  ident: CR10
  article-title: The thrombospondins
  publication-title: Cold Spring Harb Perspect Biol
  doi: 10.1101/cshperspect.a009712
  contributor:
    fullname: Lawler
– volume: 43
  start-page: 447
  year: 2011
  end-page: 456
  ident: CR33
  article-title: Deciphering the luteal transcriptome: potential mechanisms mediating stage-specific luteolytic response of the corpus luteum to prostaglandin F(2)alpha
  publication-title: Physiol Genomics
  doi: 10.1152/physiolgenomics.00155.2010
  contributor:
    fullname: Mondal
– volume: 11
  start-page: 3004
  year: 2012
  end-page: 3018
  ident: CR5
  article-title: Proteomic characterization of histotroph during the preimplantation phase of the estrous cycle in cattle
  publication-title: J Proteome Res
  doi: 10.1021/pr300144q
  contributor:
    fullname: Mullen
– volume: 154
  start-page: F45
  year: 2017
  end-page: F59
  ident: CR13
  article-title: Paracrine and endocrine actions of interferon tau (IFNT)
  publication-title: Reproduction
  doi: 10.1530/REP-17-0315
  contributor:
    fullname: Spencer
– volume: 91
  start-page: 58
  year: 2014
  ident: CR9
  article-title: Functions and transcriptional regulation of thrombospondins and their interrelationship with fibroblast growth factor-2 in bovine luteal cells
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.114.121020
  contributor:
    fullname: Meidan
– volume: 93
  start-page: 146
  year: 2015
  ident: CR46
  article-title: Temporal Release, Paracrine and Endocrine Actions of Ovine Conceptus-Derived Interferon-Tau During Early Pregnancy
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.115.132860
  contributor:
    fullname: Romero
– volume: 20
  start-page: 259
  year: 1999
  end-page: 264
  ident: CR14
  article-title: Trophoblast interferons
  publication-title: Placenta
  doi: 10.1053/plac.1998.0381
  contributor:
    fullname: Ezashi
– volume: 142
  start-page: 879
  year: 2011
  end-page: 892
  ident: CR48
  article-title: Possible involvement of IFNT in lymphangiogenesis in the corpus luteum during the maternal recognition period in the cow
  publication-title: Reproduction
  doi: 10.1530/REP-11-0157
  contributor:
    fullname: Nitta
– volume: 45
  start-page: 1095
  year: 2013
  end-page: 1108
  ident: CR18
  article-title: Pregnancy-associated genes contribute to antiluteolytic mechanisms in ovine corpus luteum
  publication-title: Physiol Genomics
  doi: 10.1152/physiolgenomics.00082.2013
  contributor:
    fullname: Romero
– volume: 66
  start-page: 1505
  year: 2002
  end-page: 1514
  ident: CR37
  article-title: Transcriptional regulation of the cyclooxygenase-2 gene changes from protein kinase (PK) A- to PKC-dependence after luteinization of granulosa cells
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod66.5.1505
  contributor:
    fullname: Wiltbank
– volume: 66
  start-page: 393
  year: 2002
  end-page: 400
  ident: CR19
  article-title: Roles of Stat1, Stat2, and interferon regulatory factor-9 (IRF-9) in interferon tau regulation of IRF-1
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod66.2.393
  contributor:
    fullname: Stewart
– volume: 138
  start-page: 581
  year: 2009
  end-page: 588
  ident: CR69
  article-title: FGF2 is crucial for the development of bovine luteal endothelial networks
  publication-title: Reproduction
  doi: 10.1530/REP-09-0030
  contributor:
    fullname: Woad
– volume: 150
  start-page: 217
  year: 2015
  end-page: 225
  ident: CR49
  article-title: Possible role of interferon tau on the bovine corpus luteum and neutrophils during the early pregnancy
  publication-title: Reproduction
  doi: 10.1530/REP-15-0085
  contributor:
    fullname: Shirasuna
– volume: 22
  start-page: 133
  year: 2019
  end-page: 144
  ident: CR66
  article-title: The calcium-binding type III repeats domain of thrombospondin-2 binds to fibroblast growth factor 2 (FGF2)
  publication-title: Angiogenesis
  doi: 10.1007/s10456-018-9644-3
  contributor:
    fullname: Rusnati
– volume: 3
  start-page: 745
  year: 2011
  end-page: 767
  ident: CR41
  article-title: Uterine receptivity to implantation of blastocysts in mammals
  publication-title: Front Biosci (Schol Ed)
  doi: 10.2741/s184
  contributor:
    fullname: Burghardt
– volume: 52
  start-page: 353
  year: 2006
  end-page: 361
  ident: CR54
  article-title: Nitric oxide induces apoptosis in bovine luteal cells
  publication-title: J Reprod Dev
  doi: 10.1262/jrd.17092
  contributor:
    fullname: Skarzynski
– volume: 79
  start-page: 263
  year: 1999
  end-page: 323
  ident: CR7
  article-title: Luteolysis: a neuroendocrine-mediated event
  publication-title: Physiol Rev
  doi: 10.1152/physrev.1999.79.2.263
  contributor:
    fullname: Lamsa
– volume: 7
  year: 2017
  ident: CR32
  article-title: Hypothalamic effects of progesterone on regulation of the pulsatile and surge release of luteinising hormone in female rats
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-08805-1
  contributor:
    fullname: He
– volume: 109
  start-page: 155
  year: 2001
  end-page: 162
  ident: CR40
  article-title: Stimulatory and synergistic effects of luteinising hormone and insulin like growth factor 1 on the secretion of vascular endothelial growth factor and progesterone of cultured bovine granulosa cells
  publication-title: Exp Clin Endocrinol Diabetes
  doi: 10.1055/s-2001-14839
  contributor:
    fullname: Miyamoto
– volume: 285
  start-page: 8733
  year: 2010
  end-page: 8742
  ident: CR11
  article-title: Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M109.085605
  contributor:
    fullname: Colombo
– volume: 82
  start-page: 725
  year: 2010
  end-page: 735
  ident: CR17
  article-title: Uterine vein infusion of interferon tau (IFNT) extends luteal life span in ewes
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.109.079467
  contributor:
    fullname: Bott
– volume: 5
  start-page: 475
  year: 2015
  end-page: 487
  ident: CR56
  article-title: The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics
  publication-title: Cancer Discov
  doi: 10.1158/2159-8290.CD-15-0011
  contributor:
    fullname: Faber
– volume: 25
  start-page: 372
  year: 2013
  end-page: 386
  ident: CR64
  article-title: Fibroblast growth factor 2 induces the precocious development of endothelial cell networks in bovine luteinising follicular cells
  publication-title: Reproduction, Fertility and Development
  doi: 10.1071/RD12182
  contributor:
    fullname: Robinson
– volume: 94
  start-page: 25
  year: 2016
  ident: CR34
  article-title: Thrombospondin-1 Affects Bovine Luteal Function via Transforming Growth Factor-Beta1-Dependent and Independent Actions
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.115.135822
  contributor:
    fullname: Meidan
– volume: 80
  start-page: 1
  year: 2000
  end-page: 29
  ident: CR1
  article-title: Mechanisms controlling the function and life span of the corpus luteum
  publication-title: Physiol Rev
  doi: 10.1152/physrev.2000.80.1.1
  contributor:
    fullname: McIntush
– volume: 124
  start-page: 2314
  year: 1989
  end-page: 2320
  ident: CR31
  article-title: Differential effects of luteinizing hormone on intracellular free Ca2+ in small and large bovine luteal cells
  publication-title: Endocrinology
  doi: 10.1210/endo-124-5-2314
  contributor:
    fullname: Hansel
– volume: 85
  start-page: 483
  year: 1989
  end-page: 487
  ident: CR27
  article-title: Cellular composition of the cyclic corpus luteum of the cow
  publication-title: J Reprod Fertil
  doi: 10.1530/jrf.0.0850483
  contributor:
    fullname: D’Occhio
– volume: 388
  start-page: 300
  year: 1997
  end-page: 304
  ident: CR58
  article-title: X-linked IAP is a direct inhibitor of cell-death proteases
  publication-title: Nature
  doi: 10.1038/40901
  contributor:
    fullname: Reed
– volume: 13
  start-page: e0194456
  year: 2018
  ident: CR71
  article-title: Genomic profiling of bovine corpus luteum maturation
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0194456
  contributor:
    fullname: Kfir
– volume: 102
  start-page: 2188
  year: 2017
  end-page: 2198
  ident: CR36
  article-title: The Adequate Corpus Luteum: miR-96 Promotes Luteal Cell Survival and Progesterone Production
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2017-00259
  contributor:
    fullname: Donadeu
– volume: 58
  start-page: 849
  year: 1998
  end-page: 856
  ident: CR30
  article-title: Characterization of messenger ribonucleic acid expression for prostaglandin F2 alpha and luteinizing hormone receptors in various bovine luteal cell types
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod58.3.849
  contributor:
    fullname: Meidan
– volume: 29
  start-page: 1063
  year: 1983
  end-page: 1068
  ident: CR28
  article-title: Prostacyclin, prostaglandin F2 alpha and progesterone production by bovine luteal cells during the estrous cycle
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod29.5.1063
  contributor:
    fullname: Hansel
– volume: 3
  start-page: 1101
  year: 2008
  end-page: 1108
  ident: CR70
  article-title: Analyzing real-time PCR data by the comparative C(T) method
  publication-title: Nat Protoc
  doi: 10.1038/nprot.2008.73
  contributor:
    fullname: Livak
– volume: 81
  start-page: 784
  year: 2009
  end-page: 794
  ident: CR2
  article-title: Progesterone-regulated changes in endometrial gene expression contribute to advanced conceptus development in cattle
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.108.074336
  contributor:
    fullname: Forde
– volume: 75
  start-page: 1449
  year: 2008
  end-page: 1456
  ident: CR63
  article-title: Effect of local neutralization of basic fibroblast growth factor or vascular endothelial growth factor by a specific antibody on the development of the corpus luteum in the cow
  publication-title: Mol Reprod Dev
  doi: 10.1002/mrd.20878
  contributor:
    fullname: Yamashita
– volume: 98
  start-page: 366
  year: 2018
  end-page: 375
  ident: CR67
  article-title: Fibroblast growth factor-2 and transforming growth factor-beta1 oppositely regulate miR-221 that targets thrombospondin-1 in bovine luteal endothelial cells
  publication-title: Biol Reprod
  doi: 10.1093/biolre/iox167
  contributor:
    fullname: Meidan
– volume: 104
  start-page: 1
  year: 1995
  end-page: 5
  ident: CR42
  article-title: Progesterone inhibition of the development of the luteolytic signal in cows
  publication-title: J Reprod Fertil
  doi: 10.1530/jrf.0.1040001
  contributor:
    fullname: Lamming
– volume: 354
  start-page: 869
  year: 2013
  end-page: 880
  ident: CR38
  article-title: Increasing cell plating density mimics an early post-LH stage in cultured bovine granulosa cells
  publication-title: Cell Tissue Res
  doi: 10.1007/s00441-013-1712-9
  contributor:
    fullname: Vanselow
– volume: 3
  start-page: 1241
  year: 2010
  ident: CR12
  article-title: Thrombospondin-1 as a Paradigm for the Development of Antiangiogenic Agents Endowed with Multiple Mechanisms of Action
  publication-title: Pharmaceuticals
  doi: 10.3390/ph3041241
  contributor:
    fullname: Taraboletti
– volume: 25
  start-page: 402
  year: 2001
  end-page: 408
  ident: CR72
  article-title: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
  publication-title: Methods
  doi: 10.1006/meth.2001.1262
  contributor:
    fullname: Schmittgen
– volume: 213
  start-page: 215
  year: 1996
  end-page: 229
  ident: CR43
  article-title: Tau-Interferon: pregnancy recognition signal in ruminants
  publication-title: Proc Soc Exp Biol Med
  doi: 10.3181/00379727-213-44053
  contributor:
    fullname: Bazer
– volume: 54
  start-page: 217
  year: 1999
  end-page: 228
  ident: CR53
  article-title: Intraovarian regulation of luteolysis
  publication-title: J Reprod Fertil Suppl
  contributor:
    fullname: Friedman
– volume: 64
  start-page: 654
  year: 2001
  end-page: 665
  ident: CR20
  article-title: Bovine interferon-tau stimulates the Janus kinase-signal transducer and activator of transcription pathway in bovine endometrial epithelial cells
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod64.2.654
  contributor:
    fullname: Binelli
– volume: 410
  start-page: 112
  year: 2001
  end-page: 116
  ident: CR59
  article-title: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
  publication-title: Nature
  doi: 10.1038/35065125
  contributor:
    fullname: Srinivasula
– volume: 200
  start-page: 10
  year: 2014
  end-page: 17
  ident: CR39
  article-title: Factors regulating the bovine, caprine, rat and human ovarian aromatase promoters in a bovine granulosa cell model
  publication-title: Gen Comp Endocrinol
  doi: 10.1016/j.ygcen.2014.02.008
  contributor:
    fullname: Sahmi
– volume: 81
  start-page: 1108
  year: 2014
  end-page: 1115
  ident: CR22
  article-title: Enhancement of maternal recognition of pregnancy with parthenogenetic embryos in bovine embryo transfer
  publication-title: Theriogenology
  doi: 10.1016/j.theriogenology.2014.01.039
  contributor:
    fullname: Hirayama
– volume: 14
  start-page: 75
  year: 2014
  end-page: 82
  ident: CR26
  article-title: Ever-changing cell interactions during the life span of the corpus luteum: relevance to luteal regression
  publication-title: Reprod Biol
  doi: 10.1016/j.repbio.2013.12.004
  contributor:
    fullname: Meidan
– volume: 88
  start-page: 144
  year: 2013
  ident: CR23
  article-title: Endocrine delivery of interferon tau protects the corpus luteum from prostaglandin F2 alpha-induced luteolysis in ewes
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.112.105684
  contributor:
    fullname: Antoniazzi
– volume: 43
  start-page: 913
  year: 1990
  end-page: 921
  ident: CR29
  article-title: differentiation of bovine theca and granulosa cells into small and large luteal-like cells: morphological and functional characteristics
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod43.6.913
  contributor:
    fullname: Aberdam
– volume: 87
  start-page: 124
  year: 2012
  ident: CR4
  article-title: Effects of low progesterone on the endometrial transcriptome in cattle
  publication-title: Biol Reprod
  doi: 10.1093/biolreprod/87.s1.124
  contributor:
    fullname: Forde
– volume: 32
  start-page: 4225
  year: 2012
  end-page: 4233
  ident: CR57
  article-title: Regulation of cancer cell survival by BCL2 family members upon prolonged mitotic arrest: opportunities for anticancer therapy
  publication-title: Anticancer Res
  contributor:
    fullname: Juin
– volume: 149
  start-page: 1252
  year: 2008
  end-page: 1259
  ident: CR16
  article-title: Expression of interferon (IFN)-stimulated genes in extrauterine tissues during early pregnancy in sheep is the consequence of endocrine IFN-tau release from the uterine vein
  publication-title: Endocrinology
  doi: 10.1210/en.2007-0863
  contributor:
    fullname: Oliveira
– volume: 154
  start-page: 559
  year: 2017
  end-page: 568
  ident: CR25
  article-title: Interferon-tau promotes luteal endothelial cell survival and inhibits specific luteolytic genes in bovine corpus luteum
  publication-title: Reproduction
  doi: 10.1530/REP-17-0290
  contributor:
    fullname: Basavaraja
– volume: 29
  start-page: 68
  year: 2009
  end-page: 82
  ident: CR61
  article-title: Death receptor-induced activation of the Chk2- and histone H2AX-associated DNA damage response pathways
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.00581-08
  contributor:
    fullname: Pommier
– volume: 275
  start-page: 9390
  year: 2000
  end-page: 9395
  ident: CR60
  article-title: Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
  publication-title: J Biol Chem
  doi: 10.1074/jbc.275.13.9390
  contributor:
    fullname: Bonner
– volume: 37
  start-page: 91
  year: 1989
  end-page: 99
  ident: CR45
  article-title: Antiluteolytic effects of bovine trophoblast protein-1
  publication-title: J Reprod Fertil Suppl
  contributor:
    fullname: Thatcher
– volume: 199
  start-page: 373
  year: 1992
  end-page: 384
  ident: CR15
  article-title: Mediators of maternal recognition of pregnancy in mammals
  publication-title: Proc Soc Exp Biol Med
  doi: 10.3181/00379727-199-43371A
  contributor:
    fullname: Bazer
– volume: 52
  start-page: 353
  year: 2006
  ident: 51152_CR54
  publication-title: J Reprod Dev
  doi: 10.1262/jrd.17092
  contributor:
    fullname: AJ Korzekwa
– volume: 20
  start-page: 259
  year: 1999
  ident: 51152_CR14
  publication-title: Placenta
  doi: 10.1053/plac.1998.0381
  contributor:
    fullname: RM Roberts
– volume: 7
  year: 2017
  ident: 51152_CR32
  publication-title: Sci Rep
  doi: 10.1038/s41598-017-08805-1
  contributor:
    fullname: W He
– volume: 94
  start-page: 25
  year: 2016
  ident: 51152_CR34
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.115.135822
  contributor:
    fullname: S Farberov
– volume: 285
  start-page: 8733
  year: 2010
  ident: 51152_CR11
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M109.085605
  contributor:
    fullname: G Colombo
– volume: 81
  start-page: 784
  year: 2009
  ident: 51152_CR2
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.108.074336
  contributor:
    fullname: N Forde
– volume: 13
  start-page: e0194456
  year: 2018
  ident: 51152_CR71
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0194456
  contributor:
    fullname: S Kfir
– volume: 45
  start-page: 1095
  year: 2013
  ident: 51152_CR18
  publication-title: Physiol Genomics
  doi: 10.1152/physiolgenomics.00082.2013
  contributor:
    fullname: JJ Romero
– volume: 43
  start-page: 913
  year: 1990
  ident: 51152_CR29
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod43.6.913
  contributor:
    fullname: R Meidan
– volume: 280
  start-page: 10357
  year: 2005
  ident: 51152_CR51
  publication-title: J Biol Chem
  doi: 10.1074/jbc.M409596200
  contributor:
    fullname: VK Yadav
– volume: 93
  start-page: 146
  year: 2015
  ident: 51152_CR46
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.115.132860
  contributor:
    fullname: JJ Romero
– volume: 32
  start-page: 4225
  year: 2012
  ident: 51152_CR57
  publication-title: Anticancer Res
  contributor:
    fullname: S Barille-Nion
– volume: 62
  start-page: 501
  issue: 5
  year: 2016
  ident: 51152_CR62
  publication-title: J Reprod Dev
  doi: 10.1262/jrd.2016-056
  contributor:
    fullname: B Berisha
– volume: 37
  start-page: 91
  year: 1989
  ident: 51152_CR45
  publication-title: J Reprod Fertil Suppl
  contributor:
    fullname: WW Thatcher
– volume: 149
  start-page: 1252
  year: 2008
  ident: 51152_CR16
  publication-title: Endocrinology
  doi: 10.1210/en.2007-0863
  contributor:
    fullname: JF Oliveira
– volume: 410
  start-page: 112
  year: 2001
  ident: 51152_CR59
  publication-title: Nature
  doi: 10.1038/35065125
  contributor:
    fullname: SM Srinivasula
– volume: 85
  start-page: 483
  year: 1989
  ident: 51152_CR27
  publication-title: J Reprod Fertil
  doi: 10.1530/jrf.0.0850483
  contributor:
    fullname: JD O’Shea
– volume: 109
  start-page: 155
  year: 2001
  ident: 51152_CR40
  publication-title: Exp Clin Endocrinol Diabetes
  doi: 10.1055/s-2001-14839
  contributor:
    fullname: D Schams
– volume: 5
  start-page: 475
  year: 2015
  ident: 51152_CR56
  publication-title: Cancer Discov
  doi: 10.1158/2159-8290.CD-15-0011
  contributor:
    fullname: AN Hata
– volume: 154
  start-page: F45
  year: 2017
  ident: 51152_CR13
  publication-title: Reproduction
  doi: 10.1530/REP-17-0315
  contributor:
    fullname: TR Hansen
– volume: 29
  start-page: 1063
  year: 1983
  ident: 51152_CR28
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod29.5.1063
  contributor:
    fullname: RA Milvae
– volume: 66
  start-page: 393
  year: 2002
  ident: 51152_CR19
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod66.2.393
  contributor:
    fullname: MD Stewart
– volume: 11
  start-page: 3004
  year: 2012
  ident: 51152_CR5
  publication-title: J Proteome Res
  doi: 10.1021/pr300144q
  contributor:
    fullname: MP Mullen
– volume: 93
  start-page: 1000
  year: 2010
  ident: 51152_CR24
  publication-title: J Dairy Sci
  doi: 10.3168/jds.2009-2529
  contributor:
    fullname: L Yang
– volume: 75
  start-page: 1449
  year: 2008
  ident: 51152_CR63
  publication-title: Mol Reprod Dev
  doi: 10.1002/mrd.20878
  contributor:
    fullname: H Yamashita
– volume: 25
  start-page: 372
  year: 2013
  ident: 51152_CR64
  publication-title: Reproduction, Fertility and Development
  doi: 10.1071/RD12182
  contributor:
    fullname: M Laird
– volume: 3
  start-page: 1241
  year: 2010
  ident: 51152_CR12
  publication-title: Pharmaceuticals
  doi: 10.3390/ph3041241
  contributor:
    fullname: M Rusnati
– volume: 58
  start-page: 849
  year: 1998
  ident: 51152_CR30
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod58.3.849
  contributor:
    fullname: R Mamluk
– volume: 14
  start-page: 75
  year: 2014
  ident: 51152_CR26
  publication-title: Reprod Biol
  doi: 10.1016/j.repbio.2013.12.004
  contributor:
    fullname: GW Smith
– volume: 78
  start-page: 1921
  year: 1995
  ident: 51152_CR44
  publication-title: J Dairy Sci
  doi: 10.3168/jds.S0022-0302(95)76817-5
  contributor:
    fullname: MD Meyer
– volume: 354
  start-page: 869
  year: 2013
  ident: 51152_CR38
  publication-title: Cell Tissue Res
  doi: 10.1007/s00441-013-1712-9
  contributor:
    fullname: A Baufeld
– volume: 75
  start-page: 289
  year: 2006
  ident: 51152_CR3
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.106.052944
  contributor:
    fullname: MC Satterfield
– ident: 51152_CR35
  doi: 10.1530/REP-18-0530
– volume: 65
  start-page: 1038
  year: 2001
  ident: 51152_CR21
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod65.4.1038
  contributor:
    fullname: Y Choi
– volume: 138
  start-page: 581
  year: 2009
  ident: 51152_CR69
  publication-title: Reproduction
  doi: 10.1530/REP-09-0030
  contributor:
    fullname: KJ Woad
– volume: 54
  start-page: 217
  year: 1999
  ident: 51152_CR53
  publication-title: J Reprod Fertil Suppl
  contributor:
    fullname: R Meidan
– volume: 132
  start-page: 249
  year: 1993
  ident: 51152_CR52
  publication-title: Endocrinology
  doi: 10.1210/endo.132.1.8419126
  contributor:
    fullname: JL Juengel
– volume: 200
  start-page: 10
  year: 2014
  ident: 51152_CR39
  publication-title: Gen Comp Endocrinol
  doi: 10.1016/j.ygcen.2014.02.008
  contributor:
    fullname: F Sahmi
– volume: 143
  start-page: 35
  year: 2012
  ident: 51152_CR65
  publication-title: Reproduction
  doi: 10.1530/REP-11-0277
  contributor:
    fullname: KJ Woad
– volume: 3
  start-page: 745
  year: 2011
  ident: 51152_CR41
  publication-title: Front Biosci (Schol Ed)
  doi: 10.2741/s184
  contributor:
    fullname: FW Bazer
– volume: 25
  start-page: 402
  year: 2001
  ident: 51152_CR72
  publication-title: Methods
  doi: 10.1006/meth.2001.1262
  contributor:
    fullname: KJ Livak
– volume: 66
  start-page: 1505
  year: 2002
  ident: 51152_CR37
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod66.5.1505
  contributor:
    fullname: YL Wu
– volume: 10
  year: 2012
  ident: 51152_CR47
  publication-title: Reprod Biol Endocrinol
  doi: 10.1186/1477-7827-10-21
  contributor:
    fullname: S Matsuyama
– volume: 22
  start-page: 133
  year: 2019
  ident: 51152_CR66
  publication-title: Angiogenesis
  doi: 10.1007/s10456-018-9644-3
  contributor:
    fullname: M Rusnati
– volume: 3
  start-page: 1101
  year: 2008
  ident: 51152_CR70
  publication-title: Nat Protoc
  doi: 10.1038/nprot.2008.73
  contributor:
    fullname: TD Schmittgen
– volume: 79
  start-page: 263
  year: 1999
  ident: 51152_CR7
  publication-title: Physiol Rev
  doi: 10.1152/physrev.1999.79.2.263
  contributor:
    fullname: JA McCracken
– volume: 88
  start-page: 144
  year: 2013
  ident: 51152_CR23
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.112.105684
  contributor:
    fullname: AQ Antoniazzi
– volume: 199
  start-page: 373
  year: 1992
  ident: 51152_CR15
  publication-title: Proc Soc Exp Biol Med
  doi: 10.3181/00379727-199-43371A
  contributor:
    fullname: FW Bazer
– volume: 29
  start-page: 68
  year: 2009
  ident: 51152_CR61
  publication-title: Mol Cell Biol
  doi: 10.1128/MCB.00581-08
  contributor:
    fullname: S Solier
– volume: 142
  start-page: 879
  year: 2011
  ident: 51152_CR48
  publication-title: Reproduction
  doi: 10.1530/REP-11-0157
  contributor:
    fullname: A Nitta
– volume: 86
  start-page: 92
  year: 2012
  ident: 51152_CR8
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.111.095067
  contributor:
    fullname: Y Zalman
– volume: 64
  start-page: 654
  year: 2001
  ident: 51152_CR20
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod64.2.654
  contributor:
    fullname: M Binelli
– volume: 98
  start-page: 366
  year: 2018
  ident: 51152_CR67
  publication-title: Biol Reprod
  doi: 10.1093/biolre/iox167
  contributor:
    fullname: S Farberov
– volume: 81
  start-page: 1108
  year: 2014
  ident: 51152_CR22
  publication-title: Theriogenology
  doi: 10.1016/j.theriogenology.2014.01.039
  contributor:
    fullname: H Hirayama
– volume: 213
  start-page: 215
  year: 1996
  ident: 51152_CR43
  publication-title: Proc Soc Exp Biol Med
  doi: 10.3181/00379727-213-44053
  contributor:
    fullname: TE Spencer
– volume: 150
  start-page: 217
  year: 2015
  ident: 51152_CR49
  publication-title: Reproduction
  doi: 10.1530/REP-15-0085
  contributor:
    fullname: K Shirasuna
– volume: 80
  start-page: 1
  year: 2000
  ident: 51152_CR1
  publication-title: Physiol Rev
  doi: 10.1152/physrev.2000.80.1.1
  contributor:
    fullname: GD Niswender
– volume: 3
  start-page: a009712
  year: 2011
  ident: 51152_CR10
  publication-title: Cold Spring Harb Perspect Biol
  doi: 10.1101/cshperspect.a009712
  contributor:
    fullname: JC Adams
– volume: 151
  start-page: 187
  year: 2016
  ident: 51152_CR55
  publication-title: Reproduction
  doi: 10.1530/REP-15-0302
  contributor:
    fullname: J Lee
– volume: 104
  start-page: 1
  year: 1995
  ident: 51152_CR42
  publication-title: J Reprod Fertil
  doi: 10.1530/jrf.0.1040001
  contributor:
    fullname: GE Mann
– start-page: 572
  volume-title: Pharmaceuticals (Basel)
  year: 2010
  ident: 51152_CR68
  contributor:
    fullname: M Raica
– volume: 43
  start-page: 447
  year: 2011
  ident: 51152_CR33
  publication-title: Physiol Genomics
  doi: 10.1152/physiolgenomics.00155.2010
  contributor:
    fullname: M Mondal
– volume: 275
  start-page: 9390
  year: 2000
  ident: 51152_CR60
  publication-title: J Biol Chem
  doi: 10.1074/jbc.275.13.9390
  contributor:
    fullname: EP Rogakou
– volume: 91
  start-page: 58
  year: 2014
  ident: 51152_CR9
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.114.121020
  contributor:
    fullname: S Farberov
– volume: 154
  start-page: 559
  year: 2017
  ident: 51152_CR25
  publication-title: Reproduction
  doi: 10.1530/REP-17-0290
  contributor:
    fullname: R Basavaraja
– volume: 388
  start-page: 300
  year: 1997
  ident: 51152_CR58
  publication-title: Nature
  doi: 10.1038/40901
  contributor:
    fullname: QL Deveraux
– volume: 124
  start-page: 2314
  year: 1989
  ident: 51152_CR31
  publication-title: Endocrinology
  doi: 10.1210/endo-124-5-2314
  contributor:
    fullname: HW Alila
– volume: 82
  start-page: 725
  year: 2010
  ident: 51152_CR17
  publication-title: Biol Reprod
  doi: 10.1095/biolreprod.109.079467
  contributor:
    fullname: RC Bott
– volume: 143
  start-page: 1495
  year: 2002
  ident: 51152_CR50
  publication-title: Endocrinology
  doi: 10.1210/endo.143.4.8726
  contributor:
    fullname: SF Carambula
– volume: 102
  start-page: 2188
  year: 2017
  ident: 51152_CR36
  publication-title: J Clin Endocrinol Metab
  doi: 10.1210/jc.2017-00259
  contributor:
    fullname: BT Mohammed
– volume: 87
  start-page: 124
  year: 2012
  ident: 51152_CR4
  publication-title: Biol Reprod
  doi: 10.1093/biolreprod/87.s1.124
  contributor:
    fullname: N Forde
– volume: 8
  start-page: 70
  issue: Suppl 1
  year: 2014
  ident: 51152_CR6
  publication-title: Animal
  doi: 10.1017/S1751731114000585
  contributor:
    fullname: MC Wiltbank
SSID ssj0000529419
Score 2.3852506
Snippet Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here whether IFNT...
Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here...
Abstract Interferon-tau (IFNT), serves as a signal to maintain the corpus luteum (CL) during early pregnancy in domestic ruminants. We investigated here...
SourceID doaj
pubmedcentral
proquest
crossref
pubmed
springer
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 14682
SubjectTerms 13
13/1
13/106
13/2
13/31
38
38/77
38/90
631/80/82/23
692/163
82
Animals
Apoptosis
Apoptosis - genetics
Bcl-x protein
Caspase
Caspase-3
Cattle
Cell death
Cell survival
Cell Survival - genetics
Cell viability
Corpus luteum
Corpus Luteum - growth & development
Corpus Luteum - metabolism
Domestic animals
Endometrium - growth & development
Endometrium - metabolism
Female
Fibroblast growth factor 2
Gene Expression Regulation - genetics
Granulosa cells
Granulosa Cells - metabolism
Humanities and Social Sciences
Interferon
Interferon Type I - genetics
Kinases
Luteal Cells - metabolism
Mcl-1 protein
multidisciplinary
Phosphorylation
Pregnancy
Pregnancy Proteins - genetics
Proteins
Science
Science (multidisciplinary)
Sheep - genetics
Sheep - growth & development
Stat1 protein
Thrombospondin
XIAP protein
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Title Interferon-Tau Exerts Direct Prosurvival and Antiapoptotic Actions in Luteinized Bovine Granulosa Cells
URI https://link.springer.com/article/10.1038/s41598-019-51152-6
https://www.ncbi.nlm.nih.gov/pubmed/31605002
https://www.proquest.com/docview/2304115782
https://search.proquest.com/docview/2305031199
https://pubmed.ncbi.nlm.nih.gov/PMC6789004
https://doaj.org/article/3326da401a86496fb5e8ca0ccc2b3ac7
Volume 9
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