Non-coding RNAs in lung cancer: emerging regulators of angiogenesis

• Published in: Journal of translational medicine Vol. 20; no. 1; pp. 1 - 11
• Main Authors: Liao, Yajie, Wu, Xudong, Wu, Mengyu, Fang, Yuan, Li, Jie, Tang, Weiqiang
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 02.08.2022; BioMed Central; BMC
• Subjects: Angiogenesis; Antiangiogenic agents; Binding sites; Cancer therapies; Care and treatment; Cell growth; Development and progression; Drug development; Drugs; Fibroblasts; Gene expression; Genetic aspects; Health aspects; Hypoxia; Lung cancer; Mechanisms; Medical prognosis; Metastasis; MicroRNAs; Neovascularization; Non-coding RNA; Non-coding RNAs; Physiology; Review; RNA; Tumors; Vascular endothelial growth factor; China

Lung cancer is the second cancer and the leading cause of tumor-related mortality worldwide. Angiogenesis is a crucial hallmark of cancer development and a promising target in lung cancer. However, the anti-angiogenic drugs currently used in the clinic do not achieve long-term efficacy and are accom...