Trimetazidine and exercise provide comparable improvements to high fat diet-induced muscle dysfunction through enhancement of mitochondrial quality control - Zhang, Wenliang; You, Baiyang; Qi, Dake; Qiu, Ling; Ripley-Gonzalez, Jeffrey W.; Zheng, Fan; Fu, Siqian; Li, Cui; Dun, Yaoshan; Liu, Suixin (Scientific reports, 2021)
Keywords: 692/163; 692/308/153; 692/308/2778; Animal models; Animals; Atrophy; Cell culture; Cell Line; Combined Modality Therapy; Diet; Diet, High-Fat - adverse effects; Disease Models, Animal; High fat diet; Humanities and Social Sciences; Humans; Lipid Metabolism - drug effects; Lipid peroxidation; Male; Metabolism; Mice; Mitochondria; Mitochondria - drug effects; Mitochondria - metabolism; multidisciplinary; Muscle, Skeletal - drug effects; Muscle, Skeletal - metabolism; Muscle, Skeletal - physiopathology; Muscular Atrophy - etiology; Muscular Atrophy - metabolism; Muscular Atrophy - physiopathology; Muscular Atrophy - therapy; Musculoskeletal system; Myoblasts; Obesity; Obesity - etiology; Obesity - metabolism; Obesity - therapy; Oxidation; Oxidation-Reduction; Palmitic acid; Palmitic Acid - toxicity; Physical Conditioning, Animal; Quality control; Science; Science (multidisciplinary); Skeletal muscle; Trimetazidine; Trimetazidine - pharmacology; Trimetazidine - therapeutic use