The bidirectional association of C-peptide with cardiovascular risk in nondiabetic adults and patients with newly diagnosed type 2 diabetes mellitus: a retrospective cohort study

• Published in: Cardiovascular diabetology Vol. 21; no. 1; pp. 1 - 11
• Main Authors: Yan, Shuang-Tong, Sun, Jing, Gu, Zhao-Yan, Miao, Xin-Yu, Ma, Li-Chao, Sun, Ban-Ruo, Fu, Xiao-Min, Liu, Hong-Zhou, Yang, Guang, Fang, Fu-Sheng, Li, Hong
• Format: Journal Article
• Language: English
• Published: London BioMed Central 03.10.2022; BMC
• Subjects: Angina pectoris; Biomarkers; C-peptide; C-reactive protein; Calcium-binding protein; Cardiac troponin T; Cardiovascular disease; Cardiovascular diseases; Cardiovascular events; Cohort analysis; Coronary vessels; Diabetes; Diabetes mellitus (non-insulin dependent); Fasting; Glucose; Glucose metabolism; Heart attacks; Hemoglobin; Hospitals; Hypertension; Insulin; Insulin resistance; Laboratories; Medical records; Metabolism; Patients; Peptides; Stroke; Troponin; Troponin T; Vein & artery diseases; United States > US; Japan

Background Recent literature reported the biological role of C-peptide, but this role is still controversial and unclear. The primary aim of this study was to investigate associations between C-peptide and cardiovascular biomarkers as well as events. Methods A total of 55636 participants who had a h...