MD2 activation by direct AGE interaction drives inflammatory diabetic cardiomyopathy - Wang, Yi; Luo, Wu; Han, Jibo; Khan, Zia A.; Fang, Qilu; Jin, Yiyi; Chen, Xuemei; Zhang, Yali; Wang, Meihong; Qian, Jianchang; Huang, Weijian; Lum, Hazel; et al. (Nature communications, 2020)
Keywords: 13; 13/51; 13/95; 692/163/2743/137/138; 692/699/249/2510; 692/699/75/74/1540; 82/29; Activation; Advanced glycosylation end products; Age; Animals; Blotting, Western; Calorimetry; Cardiomyopathy; Cell Line; Diabetes; Diabetes mellitus; Diabetes Mellitus, Experimental - immunology; Diabetes Mellitus, Experimental - metabolism; Diabetic Cardiomyopathies - immunology; Diabetic Cardiomyopathies - metabolism; Glycation End Products, Advanced - metabolism; Glycosylation; Heart; Humanities and Social Sciences; Humans; Hyperglycemia; Immunoprecipitation; Inflammation; Lymphocyte Antigen 96 - metabolism; Male; Mice; Mice, Inbred C57BL; multidisciplinary; Rats; Rats, Sprague-Dawley; Receptors; Science; Science (multidisciplinary); Signal Transduction - genetics; Signal Transduction - physiology; TLR4 protein; Toll-Like Receptor 4 - metabolism; Toll-like receptors