Cell penetration efficiency analysis of different atomic force microscopy nanoneedles into living cells

• Published in: Scientific reports Vol. 11; no. 1; pp. 7756 - 8
• Main Authors: Penedo, Marcos, Shirokawa, Tetsuya, Alam, Mohammad Shahidul, Miyazawa, Keisuke, Ichikawa, Takehiko, Okano, Naoko, Furusho, Hirotoshi, Nakamura, Chikashi, Fukuma, Takeshi
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 08.04.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/57/2282; 639/301/930/328/1262; 639/301/930/328/968; 639/925/350/1056; 639/925/350/2093; 639/925/350/59; 639/925/930/328/1262; 639/925/930/328/968; Atomic force microscopy; Biosensors; Cell membranes; Computer engineering; Drug delivery; Drug delivery systems; Efficiency; Experiments; Humanities and Social Sciences; Life sciences; Membranes; Microscopes; Microscopy; multidisciplinary; Science; Science (multidisciplinary)

Over the last decade, nanoneedle-based systems have demonstrated to be extremely useful in cell biology. They can be used as nanotools for drug delivery, biosensing or biomolecular recognition inside cells; or they can be employed to select and sort in parallel a large number of living cells. When u...