Evidence of biologic epistasis between BDNF and SLC6A4 and implications for depression - Pezawas, L; Meyer-Lindenberg, A; Goldman, A L; Verchinski, B A; Chen, G; Kolachana, B S; Egan, M F; Mattay, V S; Hariri, A R; Weinberger, D R (Molecular psychiatry, 2008)
Keywords: Adult and adolescent clinical studies; Alleles; Amino Acid Substitution; Amygdala; Anxiety; Behavioral Sciences; Biological and medical sciences; Biological Psychology; Brain; Brain - pathology; Brain-derived neurotrophic factor; Brain-Derived Neurotrophic Factor - genetics; Care and treatment; Depression; Depression - genetics; Depression - pathology; Depression, Mental; Depressive Disorder - genetics; Depressive Disorder - pathology; Diagnosis; Epistasis; Epistasis, Genetic; European Continental Ancestry Group - genetics; Genes; Genetic aspects; Genetic disorders; Genetic engineering; Genetic epistasis; Gyrus Cinguli - pathology; Health aspects; Humans; Magnetic Resonance Imaging; Medical imaging; Medical sciences; Medicine; Medicine & Public Health; Mental depression; Mental health; Mood disorders; Neural networks; Neurogenesis; Neuroimaging; Neuromodulation; Neurosciences; Neurotrophic functions; original-article; Pharmacotherapy; Physiological aspects; Polymorphism, Genetic; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychosis; Reference Values; Risk factors; Serotonin; Serotonin Plasma Membrane Transport Proteins - genetics; Social interactions; Stress; United States; United States--US; anxiety; depression; 5-HTTLPR; BDNF; neurotrophins; neuroimaging; Mood disorder; Neurotrophin; Affect affectivity; Depression; Anxiety; Brain derived neurotrophic factor