Adjuvanted recombinant hemagglutinin H7 vaccine to highly pathogenic influenza A(H7N9) elicits high and sustained antibody responses in healthy adults

• Published in: npj vaccines Vol. 6; no. 1; pp. 41 - 8
• Main Authors: Oshansky, Christine M., King, James, Lu, Di, Zhou, James, Pavetto, Corrina, Horwith, Gary, Biscardi, Karen, Nguyen, Bai, Treanor, John J., Chen, Li-Mei, Jepson, Brett, Bright, Rick A., Johnson, Robert A., Cioce, Vittoria, Donis, Ruben O.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 19.03.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/250/255; 631/250/255/1578; 631/250/590/2291; 631/250/590/2294; 692/699/255/1578; Adjuvants; Adults; Antibodies; Biomedical and Life Sciences; Biomedicine; Epidemics; Immune system; Immunogenicity; Infectious Diseases; Influenza; Medical Microbiology; Pandemics; Public Health; Vaccine; Vaccines; Virology

An unprecedented number of human infections with avian influenza A(H7N9) in the fifth epidemic wave during the winter of 2016–2017 in China and their antigenic divergence from the viruses that emerged in 2013 prompted development of updated vaccines for pandemic preparedness. We report on the findin...