Prostasomes from four different species are able to produce extracellular adenosine triphosphate (ATP)

• Published in: Biochimica et biophysica acta Vol. 1830; no. 10; pp. 4604 - 4610
• Main Authors: Ronquist, K. Göran, Ek, Bo, Morrell, Jane, Stavreus-Evers, Anneli, Ström Holst, Bodil, Humblot, Patrice, Ronquist, Gunnar, Larsson, Anders
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2013
• Subjects: adenosine triphosphate; Adenosine Triphosphate - biosynthesis; adenosinetriphosphatase; Animals; Annan medicinsk grundvetenskap; ATP; Cattle; Dogs; Electrophoresis, Polyacrylamide Gel; energy; Energy metabolism; Extracellular ATP; Horses; Humans; in vitro studies; Male; Microvesicles; molecular weight; Organelles - metabolism; Other Basic Medicine; ova; polyacrylamide gel electrophoresis; Prostasomes; proteins; proteomics; SDS-PAGE; Seminal plasma; species; spermatozoa; Energy metabolism; Seminal plasma; Microvesicles; Extracellular ATP; Prostasomes

Prostasomes are extracellular vesicles. Intracellularly they are enclosed by another larger vesicle, a so called “storage vesicle” equivalent to a multivesicular body of late endosomal origin. Prostasomes in their extracellular context are thought to play a crucial role in fertilization. Prostasomes...