Effects of Age and Sex on the Single-Dose Pharmacokinetics and Pharmacodynamics of Apixaban - Frost, Charles E.; Song, Yan; Shenker, Andrew; Wang, Jessie; Barrett, Yu Chen; Schuster, Alan; Harris, Stuart I.; LaCreta, Frank (Clinical pharmacokinetics, 2015)
Keywords: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Area Under Curve; Dose-Response Relationship, Drug; Drug Administration Schedule; Factor Xa Inhibitors - administration & dosage; Factor Xa Inhibitors - blood; Factor Xa Inhibitors - pharmacokinetics; Female; Humans; Internal Medicine; International Normalized Ratio; Male; Medicine; Medicine & Public Health; Original; Original Research Article; Pharmacology/Toxicology; Pharmacotherapy; Pyrazoles - administration & dosage; Pyrazoles - blood; Pyrazoles - pharmacokinetics; Pyridones - administration & dosage; Pyridones - blood; Pyridones - pharmacokinetics; Regression Analysis; Sex Factors; Young Adult; International Normalize Ratio; Maximum Observe Plasma Concentration; Elderly Female; Individual Subject Data; Apixaban