Spatial structure of TLR4 transmembrane domain in bicelles provides the insight into the receptor activation mechanism
Toll-like receptors (TLRs) play a key role in the innate and adaptive immune systems. While a lot of structural data is available for the extracellular and cytoplasmic domains of TLRs, and a model of the dimeric full-length TLR3 receptor in the active state was build, the conformation of the transme...
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Published in | Scientific reports Vol. 7; no. 1; pp. 6864 - 12 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
31.07.2017
Nature Publishing Group Nature Portfolio |
Subjects | |
Online Access | Get full text |
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