Loss of SIRT1 inhibits hematopoietic stem cell aging and age-dependent mixed phenotype acute leukemia - Wang, Zhiqiang; Zhang, Chunxiao; Warden, Charles David; Liu, Zheng; Yuan, Yate-Ching; Guo, Chao; Wang, Charles; Wang, Jinhui; Wu, Xiwei; Ermel, Richard; Vonderfecht, Steven L.; Wang, Xiuli; et al. (Communications biology, 2022)
Keywords: 13/100; 13/109; 13/2; 13/31; 13/89; 14/63; 38/77; 42/41; 45/22; 45/29; 45/90; 631/532/2118/1542; 631/532/7; 692/4028/67/1990/283/1897; 82/29; Aging; Aging - genetics; Animals; Biology; Biomedical and Life Sciences; Bone marrow; Bone marrow transplantation; Genotype & phenotype; Hematological diseases; Hematopoietic stem cells; Hematopoietic Stem Cells - metabolism; Leukemia; Leukemia - genetics; Leukemia - metabolism; Life Sciences; Mice; Oxidative metabolism; Phenotype; Phenotypes; Protein biosynthesis; Protein turnover; SIRT1 protein; Sirtuin 1 - genetics; Sirtuin 1 - metabolism; Stem cell transplantation; Stem cells; Therapeutic targets; Transcription factors