Clinical evaluation of fully automated molecular diagnostic system “Simprova” for influenza virus, respiratory syncytial virus, and human metapneumovirus

• Published in: Scientific reports Vol. 10; no. 1; p. 13496
• Main Authors: Takayama, Ikuyo, Semba, Shohei, Yokono, Kota, Saito, Shinji, Nakauchi, Mina, Kubo, Hideyuki, Kaida, Atsushi, Shiomi, Masashi, Terada, Akihiro, Murakami, Kiyotaka, Kaji, Katsushi, Kiya, Keiichi, Sawada, Yoshitaka, Oba, Kunihiro, Asai, Sadasaburo, Yonekawa, Toshihiro, Watanabe, Hidetoshi, Segawa, Yuji, Notomi, Tsugunori, Kageyama, Tsutomu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 11.08.2020; Nature Publishing Group
• Subjects: 631/326; 692/700; Adolescent; Antigens; Automation; Child; Child, Preschool; Female; Gene amplification; Humanities and Social Sciences; Humans; Infant; Infant, Newborn; Infections; Influenza; Influenza A; Male; Metapneumovirus - genetics; Metapneumovirus - isolation & purification; Molecular Diagnostic Techniques - methods; multidisciplinary; Nucleic Acid Amplification Techniques - methods; Nucleic acids; Orthomyxoviridae - genetics; Orthomyxoviridae - isolation & purification; Respiratory diseases; Respiratory syncytial virus; Respiratory Syncytial Viruses - genetics; Respiratory Syncytial Viruses - isolation & purification; Respiratory tract; Respiratory tract diseases; Science; Science (multidisciplinary); Viral infections; Viruses

Influenza virus, respiratory syncytial virus, and human metapneumovirus commonly cause acute upper and lower respiratory tract infections, especially in children and the elderly. Although rapid antigen detection tests for detecting these infections have been introduced recently, these are less sensi...