Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy
Intravascular hemolysis and hemoglobinuria are associated with sickle cell nephropathy. ApoL1 is involved in cell-free hemoglobin scavenging through association with haptoglobin-related protein. APOL1 G1/G2 variants are the strongest genetic predictors of kidney disease in the general African-Americ...
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Published in | Haematologica (Roma) Vol. 100; no. 10; pp. 1275 - 1284 |
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Main Authors | , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Italy
Ferrata Storti Foundation
01.10.2015
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Subjects | |
Online Access | Get full text |
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