Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer - Zhang, Misty Shuo; Cui, Jane Di; Lee, Derek; Yuen, Vincent Wai-Hin; Chiu, David Kung-Chun; Goh, Chi Ching; Cheu, Jacinth Wing-Sum; Tse, Aki Pui-Wah; Bao, Macus Hao-Ran; Wong, Bowie Po Yee; Chen, Carrie Yiling; Wong, Chun-Ming; et al. (Nature communications, 2022)
Keywords: 13; 13/106; 14/19; 14/28; 38/15; 59/5; 631/67/2327; 64/60; 692/4020/1503/1504/1610/4029; 82/58; Animals; Carcinoma, Hepatocellular - genetics; Carcinoma, Hepatocellular - immunology; Carcinoma, Hepatocellular - pathology; Carrier Proteins - genetics; Carrier Proteins - metabolism; Cell Line, Tumor; Gene Expression Regulation, Neoplastic - immunology; Gene Knockdown Techniques; Hepatocellular carcinoma; Humanities and Social Sciences; Humans; Hypoxia; Hypoxia-inducible factor 1; Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit - genetics; Hypoxia-Inducible Factor 1, alpha Subunit - metabolism; Liver cancer; Liver Neoplasms - genetics; Liver Neoplasms - immunology; Liver Neoplasms - pathology; Membrane proteins; Membrane ruffling; Membranes; Mice; Mice, Knockout; multidisciplinary; Nutrients; Pinocytosis - drug effects; Pinocytosis - genetics; Pinocytosis - immunology; Proof of Concept Study; Proteins; Scavenging; Science; Science (multidisciplinary); Transcription; Tumor Hypoxia - genetics; Tumor Hypoxia - immunology; Xenograft Model Antitumor Assays