The Correction of Facial Morphea Lesions by Hyaluronic Acid: A Case Series and Literature Review

Introduction The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious de...

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Published inDermatology and therapy Vol. 10; no. 6; pp. 1423 - 1434
Main Authors Owczarczyk-Saczonek, Agnieszka, Kasprowicz-Furmańczyk, Marta, Kruszewska, Anna, Krajewska-Włodarczyk, Magdalena, Bechtold, Agata, Klimek, Paulina, Placek, Waldemar
Format Journal Article
LanguageEnglish
Published Cheshire Springer Healthcare 01.12.2020
Springer Nature B.V
Adis, Springer Healthcare
Subjects
Alopecia
Atrophy
Autoimmune diseases
Baldness
Case Series
Chronic illnesses
Connective tissue
Correction
Dermatology
FAL
Family medical history
Females
Fibroblasts
Fractional ablative laser
Hyaluronic acid
Inflammatory diseases
Internal Medicine
Medicine
Medicine & Public Health
Morphea
Oral and Maxillofacial Surgery
Patients
Plastic Surgery
Quality of life
Quality of Life Research
Scleroderma
Thyroid gland
FAL
Morphea
Fractional ablative laser
Hyaluronic acid
Scleroderma
Correction
Online AccessGet full text

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Abstract Introduction The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients’ quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment. Case Presentation The paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm ® Voluma or Volux, Vycross ® technology, Allergan, injected. One of the patients had additionally fractional ablative CO 2 laser (FAL) therapy. Discussion The literature provides reports on successful use of HA, polymethylmethacrylate and poly- l -lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis. Conclusions HA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.
AbstractList IntroductionThe aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients’ quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment.Case PresentationThe paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm® Voluma or Volux, Vycross® technology, Allergan, injected. One of the patients had additionally fractional ablative CO2 laser (FAL) therapy.DiscussionThe literature provides reports on successful use of HA, polymethylmethacrylate and poly-l-lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis.ConclusionsHA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.
The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients' quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment. The paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm Voluma or Volux, Vycross technology, Allergan, injected. One of the patients had additionally fractional ablative CO laser (FAL) therapy. The literature provides reports on successful use of HA, polymethylmethacrylate and poly-L-lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis. HA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.
Abstract Introduction The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients’ quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment. Case Presentation The paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm® Voluma or Volux, Vycross® technology, Allergan, injected. One of the patients had additionally fractional ablative CO2 laser (FAL) therapy. Discussion The literature provides reports on successful use of HA, polymethylmethacrylate and poly-l-lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis. Conclusions HA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.
The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients' quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment.INTRODUCTIONThe aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients' quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment.The paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm® Voluma or Volux, Vycross® technology, Allergan, injected. One of the patients had additionally fractional ablative CO2 laser (FAL) therapy.CASE PRESENTATIONThe paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm® Voluma or Volux, Vycross® technology, Allergan, injected. One of the patients had additionally fractional ablative CO2 laser (FAL) therapy.The literature provides reports on successful use of HA, polymethylmethacrylate and poly-L-lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis.DISCUSSIONThe literature provides reports on successful use of HA, polymethylmethacrylate and poly-L-lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis.HA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.CONCLUSIONSHA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.
Introduction The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to review the literature on the subject. Morphea is a chronic inflammatory disease of the connective tissue which may lead to serious deformations. The lesions located on the face particularly affect patients’ quality of life and self-esteem; thus, there is a demand for safe and effective methods of treatment. Case Presentation The paper presents three female patients aged 16, 17 and 70 with facial morphea lesions who had HA preparation Juvéderm ® Voluma or Volux, Vycross ® technology, Allergan, injected. One of the patients had additionally fractional ablative CO 2 laser (FAL) therapy. Discussion The literature provides reports on successful use of HA, polymethylmethacrylate and poly- l -lactic acid for the correction of facial defects in localized scleroderma. HA is a natural component of the extracellular matrix and it therefore minimizes the probability of immunogenicity. The application technique also plays an important role. On the other hand, FAL therapy leads to the degradation of the abnormal collagen and the induction of normal collagen synthesis. Conclusions HA injection and combination of HA application with FAL are minimally invasive, effective and safe therapeutic options for patients suffering from morphea.
Author Krajewska-Włodarczyk, Magdalena
Kasprowicz-Furmańczyk, Marta
Kruszewska, Anna
Placek, Waldemar
Owczarczyk-Saczonek, Agnieszka
Bechtold, Agata
Klimek, Paulina
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Issue 6
Keywords FAL
Morphea
Fractional ablative laser
Hyaluronic acid
Scleroderma
Correction
Language English
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Snippet Introduction The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions...
The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions and to...
IntroductionThe aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial morphea lesions...
Abstract Introduction The aim of the study is to assess the long-term safety and efficacy of hyaluronic acid (HA) administration in correction of facial...
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
springer
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 1423
SubjectTerms Alopecia
Atrophy
Autoimmune diseases
Baldness
Case Series
Chronic illnesses
Connective tissue
Correction
Dermatology
FAL
Family medical history
Females
Fibroblasts
Fractional ablative laser
Hyaluronic acid
Inflammatory diseases
Internal Medicine
Medicine
Medicine & Public Health
Morphea
Oral and Maxillofacial Surgery
Patients
Plastic Surgery
Quality of life
Quality of Life Research
Scleroderma
Thyroid gland
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Title The Correction of Facial Morphea Lesions by Hyaluronic Acid: A Case Series and Literature Review
URI https://link.springer.com/article/10.1007/s13555-020-00438-z
https://www.ncbi.nlm.nih.gov/pubmed/32876907
https://www.proquest.com/docview/3224053988
https://www.proquest.com/docview/2439628590
https://pubmed.ncbi.nlm.nih.gov/PMC7649201
https://doaj.org/article/63afe4d60bd64bedacb324fcc1d00b09
Volume 10
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