AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2 - Yang, Acong; Shao, Tie-Juan; Bofill-De Ros, Xavier; Lian, Chuanjiang; Villanueva, Patricia; Dai, Lisheng; Gu, Shuo (Nature communications, 2020)
Keywords: 38/1; 38/39; 42/109; 42/70; 45/29; 45/71; 45/77; 45/88; 45/91; 49/90; 631/337/1645; 631/337/384/331; 631/45/500; Argonaute Proteins - genetics; Argonaute Proteins - metabolism; Cancer; Decay; Degradation; DNA-Binding Proteins - genetics; DNA-Binding Proteins - metabolism; Exonuclease; Exoribonucleases - genetics; Exoribonucleases - metabolism; Gene expression; Gene Knockout Techniques; HEK293 Cells; High-Throughput Nucleotide Sequencing; Humanities and Social Sciences; Humans; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; miRNA; multidisciplinary; Mutation; Proteins; Ribonucleic acid; RNA; RNA Nucleotidyltransferases - genetics; RNA Nucleotidyltransferases - metabolism; Science; Science (multidisciplinary)