Urgency and necessity of Epstein-Barr virus prophylactic vaccines

• Published in: npj vaccines Vol. 7; no. 1; pp. 159 - 14
• Main Authors: Zhong, Ling, Krummenacher, Claude, Zhang, Wanlin, Hong, Junping, Feng, Qisheng, Chen, Yixin, Zhao, Qinjian, Zeng, Mu-Sheng, Zeng, Yi-Xin, Xu, Miao, Zhang, Xiao
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 09.12.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326/590; 631/326/596; Animal models; Antigens; Biomedical and Life Sciences; Biomedicine; Design; Epstein-Barr virus; Glycoproteins; Immunogenicity; Infections; Infectious Diseases; Medical Microbiology; Polymers; Public Health; Review; Review Article; Vaccine; Vaccines; Virology

Epstein-Barr virus (EBV), a γ-herpesvirus, is the first identified oncogenic virus, which establishes permanent infection in humans. EBV causes infectious mononucleosis and is also tightly linked to many malignant diseases. Various vaccine formulations underwent testing in different animals or in hu...