Characterising clinical Staphylococcus aureus isolates from the sinuses of patients with chronic rhinosinusitis

• Published in: Scientific reports Vol. 11; no. 1; pp. 21940 - 11
• Main Authors: Wagner Mackenzie, Brett, Zoing, Melissa, Clow, Fiona, Waite, David W., Radcliff, Fiona J., Taylor, Michael W., Biswas, Kristi, Douglas, Richard G.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 09.11.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326; 631/337; 692/308; Adult; Bacteria; Carrier State; Chronic Disease; Community composition; Comparative analysis; Cross-Sectional Studies; Female; Gene expression; Genes, Bacterial; Humanities and Social Sciences; Humans; Male; Middle Aged; multidisciplinary; Patients; Penicillin; Rhinitis; Rhinosinusitis; rRNA 16S; Science; Science (multidisciplinary); Sinusitis; Sinusitis - microbiology; Spa gene; Staphylococcal Infections - microbiology; Staphylococcus aureus; Staphylococcus aureus - genetics; Staphylococcus aureus - isolation & purification

The role of Staphylococcus aureus in the pathogenesis of the chronic sinonasal disease chronic rhinosinusitis (CRS), has not been definitively established. Comparative analyses of S. aureus isolates from CRS with those from control participants may offer insight into a possible pathogenic link betwe...