White matter variability, cognition, and disorders: a systematic review

• Published in: Brain Structure and Function Vol. 227; no. 2; pp. 529 - 544
• Main Authors: Forkel, Stephanie J., Friedrich, Patrick, Thiebaut de Schotten, Michel, Howells, Henrietta
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2022; Springer Nature B.V
• Subjects: Anatomy; Biomedical and Life Sciences; Biomedicine; Brain - diagnostic imaging; Cell Biology; Cognition; Cognition & reasoning; Cognitive ability; Cross-Sectional Studies; Diffusion Tensor Imaging; Functional morphology; Humans; Neurology; Neurosciences; Original; Original Article; Patients; Precision medicine; Structure-function relationships; Substantia alba; Systematic review; White Matter - diagnostic imaging; Biomarker; Variability; Tractography; Cognition; Personalized medicine; White matter; Patients

Inter-individual differences can inform treatment procedures and—if accounted for—have the potential to significantly improve patient outcomes. However, when studying brain anatomy, these inter-individual variations are commonly unaccounted for, despite reports of differences in gross anatomical fea...