Flavivirus infections induce a Golgi stress response in vertebrate and mosquito cells

• Published in: Scientific reports Vol. 11; no. 1; p. 23489
• Main Authors: Viettri, Mercedes, Zambrano, José L., Rosales, Romel, Caraballo, Gerson I., Gutiérrez-Escolano, Ana Lorena, Ludert, Juan E.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 06.12.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/326; 631/326/421; 631/326/596; Animals; Aquatic insects; Cells, Cultured; Cellular stress response; Chlorocebus aethiops; Culicidae - virology; Cytoplasm; Dengue fever; Flavivirus - genetics; Flavivirus Infections - virology; Golgi apparatus; Golgi Apparatus - virology; Humanities and Social Sciences; Infections; Lysis; Mesocricetus; Monensin; Mosquitoes; multidisciplinary; Replication; Science; Science (multidisciplinary); Translocation; Vector-borne diseases; Vero Cells; Vertebrates; Vertebrates - virology; Viral infections; Viral Nonstructural Proteins - genetics; Virions; Virus Replication - genetics; Viruses; Zika virus

The stress of the Golgi apparatus is an autoregulatory mechanism that is induced to compensate for greater demand in the Golgi functions. No examples of Golgi stress responses due to physiological stimuli are known. Furthermore, the impact on this organelle of viral infections that occupy the vesicu...