Monocyte subsets display age-dependent alterations at fasting and undergo non-age-dependent changes following consumption of a meal

• Published in: Immunity & ageing Vol. 19; no. 1; pp. 1 - 13
• Main Authors: Snodgrass, Ryan G., Jiang, Xiaowen, Stephensen, Charles B.
• Format: Journal Article
• Language: English
• Published: London BioMed Central Ltd 14.09.2022; BioMed Central; BMC
• Subjects: Age; Ageing; Aging; Biomarkers; Carbohydrates; CD14 antigen; CD16 antigen; Cholesterol; Classical; Fasting; High density lipoprotein; Interleukin 6; Interleukin 8; Intermediate; Laboratories; Metabolism; Monocyte; Monocyte chemoattractant protein 1; Monocytes; Neopterin; Nutrition research; Plasma; Population; Postprandial; Tumor necrosis factor; Young adults; United States > US

Background Monocytes are a heterogenous population of immune cells whose subsets and functions become substantially dysregulated with advanced age. Although much of our current understanding of the age-related changes in monocytes is derived from fasting blood samples, most people are predominately...