Molecular targeted therapy for anticancer treatment

• Published in: Experimental & molecular medicine Vol. 54; no. 10; pp. 1670 - 1694
• Main Authors: Min, Hye-Young, Lee, Ho-Young
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.10.2022; Springer Nature B.V
• Subjects: 631/67/1059/602; 692/699/67/1059/602; Antibodies, Monoclonal - therapeutic use; Antineoplastic Agents - pharmacology; Antineoplastic Agents - therapeutic use; Biomedical and Life Sciences; Biomedicine; Cancer; Cancer therapies; Chemotherapy; Drug development; Drug resistance; Drug Resistance, Neoplasm; Humans; Medical Biochemistry; Molecular Medicine; Molecular Targeted Therapy; Monoclonal antibodies; Mutation; Neoplasms - drug therapy; Neoplasms - genetics; Precision Medicine; Review; Review Article; Signal transduction; Stem Cells; Therapeutic targets; Tumor cells

Since the initial clinical approval in the late 1990s and remarkable anticancer effects for certain types of cancer, molecular targeted therapy utilizing small molecule agents or therapeutic monoclonal antibodies acting as signal transduction inhibitors has served as a fundamental backbone in precis...