Long term safety, tolerability, and efficacy of intracutaneous zolmitriptan (M207) in the acute treatment of migraine

• Published in: Journal of headache and pain Vol. 22; no. 1; pp. 37 - 6
• Main Authors: Nahas, Stephanie J., Hindiyeh, Nada, Friedman, Deborah I., Elbuluk, Nada, Kellerman, Donald J., Foreman, Pamela K., Schmidt, Peter
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 01.12.2021; Springer Nature B.V; BMC
• Subjects: Adverse events; Clinical outcomes; Double-Blind Method; Drug therapy; Erythema; Headache; Humans; Hypodermic needles; Injections; Internal Medicine; Intracutaneous; M207; Medicine; Medicine & Public Health; Microneedle; Migraine; Migraine Disorders - drug therapy; Neurology; Oxazolidinones - adverse effects; Pain; Pain Medicine; Patient safety; Placebos; Research Article; Safety; Treatment Outcome; Tryptamines - adverse effects; Intracutaneous; Migraine; Microneedle; M207

Objective To determine the long-term safety and tolerability profile of M207 in the acute treatment of migraine. Background M207 is an investigational microneedle-based system for intracutaneous delivery of zolmitriptan for the treatment of migraine attacks. Following on the positive results of a Ph...