Global epidemiology of atrial fibrillation
Key Points Atrial fibrillation (AF) is a worldwide epidemic affecting approximately 33 million people, and its rising prevalence is expected to account for increasing clinical and public health costs Australia, Europe, and the USA have the highest reported prevalence of AF (1% in the adult populatio...
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Published in | Nature reviews cardiology Vol. 11; no. 11; pp. 639 - 654 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
London
Nature Publishing Group UK
01.11.2014
Nature Publishing Group |
Subjects | |
Online Access | Get full text |
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Abstract | Key Points
Atrial fibrillation (AF) is a worldwide epidemic affecting approximately 33 million people, and its rising prevalence is expected to account for increasing clinical and public health costs
Australia, Europe, and the USA have the highest reported prevalence of AF (1% in the adult population), but the prevalence of AF in low-income and middle-income countries is probably underestimated
AF is associated with an increased risk of myocardial infarction, heart failure, stroke, dementia, and chronic kidney disease, as well as increased mortality
Treatment of patients with AF is inadequate: <50% of those at high thromboembolic risk receive anticoagulation therapy worldwide
The dearth of data on the prevalence, lifetime risk, prognosis, prevention, treatment, and economic implications of AF in many regions around the world remains to be addressed
The prevalence of atrial fibrillation (AF) is estimated to increase worldwide, mainly as a consequence of generalized population ageing. Even though the rise in AF prevalence is a global trend, data from Africa, Asia, and South America are limited and might underestimate the true frequency of AF. In this Review, the authors discuss the available epidemiological data on AF and highlight the widespread inadequacy of its treatment.
Atrial fibrillation (AF) is a major public health burden worldwide, and its prevalence is set to increase owing to widespread population ageing, especially in rapidly developing countries such as Brazil, China, India, and Indonesia. Despite the availability of epidemiological data on the prevalence of AF in North America and Western Europe, corresponding data are limited in Africa, Asia, and South America. Moreover, other observations suggest that the prevalence of AF might be underestimated—not only in low-income and middle-income countries, but also in their high-income counterparts. Future studies are required to provide precise estimations of the global AF burden, identify important risk factors in various regions worldwide, and take into consideration regional and ethnic variations in AF. Furthermore, in response to the increasing prevalence of AF, additional resources will need to be allocated globally for prevention and treatment of AF and its associated complications. In this Review, we discuss the available data on the global prevalence, risk factors, management, financial costs, and clinical burden of AF, and highlight the current worldwide inadequacy of its treatment. |
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AbstractList | Atrial fibrillation (AF) is a major public health burden worldwide, and its prevalence is set to increase owing to widespread population ageing, especially in rapidly developing countries such as Brazil, China, India, and Indonesia. Despite the availability of epidemiological data on the prevalence of AF in North America and Western Europe, corresponding data are limited in Africa, Asia, and South America. Moreover, other observations suggest that the prevalence of AF might be underestimated--not only in low-income and middle-income countries, but also in their high-income counterparts. Future studies are required to provide precise estimations of the global AF burden, identify important risk factors in various regions worldwide, and take into consideration regional and ethnic variations in AF. Furthermore, in response to the increasing prevalence of AF, additional resources will need to be allocated globally for prevention and treatment of AF and its associated complications. In this Review, we discuss the available data on the global prevalence, risk factors, management, financial costs, and clinical burden of AF, and highlight the current worldwide inadequacy of its treatment. Rahman, F. et al. Nat. Rev. Cardiol. 11, 639-654 (2014); published online 12 August 2014; doi: 10.1038/nrcardio.2014.118 Atrial fibrillation (AF) is a major public health burden worldwide, and its prevalence is set to increase owing to widespread population ageing, especially in rapidly developing countries such as Brazil, China, India, and Indonesia. Despite the availability of epidemiological data on the prevalence of AF in North America and Western Europe, corresponding data are limited in Africa, Asia, and South America. Moreover, other observations suggest that the prevalence of AF might be underestimated-not only in low-income and middle-income countries, but also in their high-income counterparts. Future studies are required to provide precise estimations of the global AF burden, identify important risk factors in various regions worldwide, and take into consideration regional and ethnic variations in AF. Furthermore, in response to the increasing prevalence of AF, additional resources will need to be allocated globally for prevention and treatment of AF and its associated complications. In this Review, we discuss the available data on the global prevalence, risk factors, management, financial costs, and clinical burden of AF, and highlight the current worldwide inadequacy of its treatment. Key Points Atrial fibrillation (AF) is a worldwide epidemic affecting approximately 33 million people, and its rising prevalence is expected to account for increasing clinical and public health costs Australia, Europe, and the USA have the highest reported prevalence of AF (1% in the adult population), but the prevalence of AF in low-income and middle-income countries is probably underestimated AF is associated with an increased risk of myocardial infarction, heart failure, stroke, dementia, and chronic kidney disease, as well as increased mortality Treatment of patients with AF is inadequate: <50% of those at high thromboembolic risk receive anticoagulation therapy worldwide The dearth of data on the prevalence, lifetime risk, prognosis, prevention, treatment, and economic implications of AF in many regions around the world remains to be addressed The prevalence of atrial fibrillation (AF) is estimated to increase worldwide, mainly as a consequence of generalized population ageing. Even though the rise in AF prevalence is a global trend, data from Africa, Asia, and South America are limited and might underestimate the true frequency of AF. In this Review, the authors discuss the available epidemiological data on AF and highlight the widespread inadequacy of its treatment. Atrial fibrillation (AF) is a major public health burden worldwide, and its prevalence is set to increase owing to widespread population ageing, especially in rapidly developing countries such as Brazil, China, India, and Indonesia. Despite the availability of epidemiological data on the prevalence of AF in North America and Western Europe, corresponding data are limited in Africa, Asia, and South America. Moreover, other observations suggest that the prevalence of AF might be underestimated—not only in low-income and middle-income countries, but also in their high-income counterparts. Future studies are required to provide precise estimations of the global AF burden, identify important risk factors in various regions worldwide, and take into consideration regional and ethnic variations in AF. Furthermore, in response to the increasing prevalence of AF, additional resources will need to be allocated globally for prevention and treatment of AF and its associated complications. In this Review, we discuss the available data on the global prevalence, risk factors, management, financial costs, and clinical burden of AF, and highlight the current worldwide inadequacy of its treatment. |
Audience | Academic |
Author | Kwan, Gene F. Rahman, Faisal Benjamin, Emelia J. |
Author_xml | – sequence: 1 givenname: Faisal surname: Rahman fullname: Rahman, Faisal organization: Department of Medicine, Boston Medical Center, Boston University School of Medicine – sequence: 2 givenname: Gene F. surname: Kwan fullname: Kwan, Gene F. organization: Department of Cardiovascular Medicine, Boston Medical Center, Boston University School of Medicine – sequence: 3 givenname: Emelia J. surname: Benjamin fullname: Benjamin, Emelia J. email: emelia@bu.edu organization: The Framingham Heart Study |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25113750$$D View this record in MEDLINE/PubMed |
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Atrial fibrillation (AF) is a worldwide epidemic affecting approximately 33 million people, and its rising prevalence is expected to account for... Atrial fibrillation (AF) is a major public health burden worldwide, and its prevalence is set to increase owing to widespread population ageing, especially in... |
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SubjectTerms | 692/308/174 692/699/75/29/1309 Atrial fibrillation Atrial Fibrillation - complications Atrial Fibrillation - epidemiology Atrial Fibrillation - prevention & control Cardiac Imaging Cardiac Surgery Cardiology Cardiovascular research Care and treatment Cost of Illness Distribution Epidemiology Global Health - statistics & numerical data Humans International aspects Medicine & Public Health Prevalence review-article Risk Factors Stroke - epidemiology Stroke - etiology |
Title | Global epidemiology of atrial fibrillation |
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