Impact of the coverage of risk-reducing salpingo-oophorectomy by the national insurance system for women with BRCA pathogenic variants in Japan

• Published in: Scientific reports Vol. 13; no. 1; p. 1018
• Main Authors: Nomura, Hidetaka, Abe, Akiko, Fusegi, Atsushi, Yoshimitsu, Teruyuki, Misaka, Satoki, Murakami, Atsushi, Matsumoto, Tsuyoshi, Tsumura, Shiho, Kanno, Motoko, Aoki, Yoichi, Netsu, Sachiho, Omi, Makiko, Tanigawa, Terumi, Okamoto, Sanshiro, Omatsu, Kohei, Yunokawa, Mayu, Kanao, Hiroyuki, Habano, Eri, Arakawa, Hiromi, Kaneko, Keika, Ueki, Arisa, Haruyama, Yurie, Inari, Hitoshi, Ueno, Takayuki
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 19.01.2023; Nature Publishing Group; Nature Portfolio
• Subjects: 631/67; 692/308; 692/4028; BRCA1 Protein - genetics; BRCA2 Protein - genetics; Breast cancer; Breast Neoplasms - genetics; Breast Neoplasms - pathology; Breast Neoplasms - surgery; Female; Genetic Predisposition to Disease; Genetic screening; Humanities and Social Sciences; Humans; Hysterectomy; Insurance coverage; Japan; Mastectomy; multidisciplinary; Mutation; Oophorectomy; Ovarian Neoplasms - genetics; Ovarian Neoplasms - prevention & control; Ovarian Neoplasms - surgery; Ovariectomy; Salpingo-oophorectomy; Science; Science (multidisciplinary); Statistical analysis; Surgery; Japan

To determine the impact of the coverage of risk-reducing salpingo-oophorectomy (RRSO) and mastectomy (RRM) as well as genetic testing for BRCA pathogenic variants by the national insurance system in Japan. We compared the clinical background of women who underwent RRSO at our institution before and...