Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging

• Published in: Nature communications Vol. 9; no. 1; pp. 644 - 11
• Main Authors: Oh, Gabriel, Ebrahimi, Sasha, Carlucci, Matthew, Zhang, Aiping, Nair, Akhil, Groot, Daniel E., Labrie, Viviane, Jia, Peixin, Oh, Edward S., Jeremian, Richie H., Susic, Miki, Shrestha, Tenjin C., Ralph, Martin R., Gordevičius, Juozas, Koncevičius, Karolis, Petronis, Art
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.02.2018; Nature Publishing Group; Nature Portfolio
• Subjects: 38/22; 38/77; 38/88; 38/90; 42/47; 49/23; 631/136/7; 631/337/176/1988; 631/80/105; 64/60; Aging; Biodiversity; Circadian rhythm; Circadian rhythms; Cytosine; Epigenetics; Humanities and Social Sciences; Machinery and equipment; multidisciplinary; Oscillations; Proteomics; Science; Science (multidisciplinary)

Circadian rhythmicity governs a remarkable array of fundamental biological functions and is mediated by cyclical transcriptomic and proteomic activities. Epigenetic factors are also involved in this circadian machinery; however, despite extensive efforts, detection and characterization of circadian...