Neonicotinoids act like endocrine disrupting chemicals in newly-emerged bees and winter bees
Accumulating evidence suggests that neonicotinoids may have long-term adverse effects on bee health, yet our understanding of how this could occur is incomplete. Pesticides can act as endocrine disrupting chemicals (EDCs) in animals providing characteristic multiphasic dose-response curves and non-l...
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Published in | Scientific reports Vol. 7; no. 1; pp. 10979 - 18 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
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Nature Publishing Group UK
08.09.2017
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Abstract | Accumulating evidence suggests that neonicotinoids may have long-term adverse effects on bee health, yet our understanding of how this could occur is incomplete. Pesticides can act as endocrine disrupting chemicals (EDCs) in animals providing characteristic multiphasic dose-response curves and non-lethal endpoints in toxicity studies. However, it is not known if neonicotinoids act as EDCs in bees. To address this issue, we performed oral acute and chronic toxicity studies including concentrations recorded in nectar and pollen, applying acetamiprid, clothianidin, imidacloprid, and thiamethoxam to bumble bees, honey bees and leafcutter bees, the three most common bee species managed for pollination. In acute toxicity studies, late-onset symptoms, such as ataxia, were recorded as non-lethal endpoints for all three bee species. Clothianidin and thiamethoxam produced biphasic dose-response curves for all three bee species. Clothianidin and thiamethoxam were extremely toxic to winter worker honey bees prior to brood production in spring, making this the most sensitive bee stage identified to date. Chronic exposure to field-realistic levels of neonicotinoids reduced bee survival and caused significant late-onset symptoms for all three bee species. Given these findings, neonicotinoid risk should be reevaluated to address the EDC-like behavior and the sensitivity of winter worker honey bees. |
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AbstractList | Accumulating evidence suggests that neonicotinoids may have long-term adverse effects on bee health, yet our understanding of how this could occur is incomplete. Pesticides can act as endocrine disrupting chemicals (EDCs) in animals providing characteristic multiphasic dose-response curves and non-lethal endpoints in toxicity studies. However, it is not known if neonicotinoids act as EDCs in bees. To address this issue, we performed oral acute and chronic toxicity studies including concentrations recorded in nectar and pollen, applying acetamiprid, clothianidin, imidacloprid, and thiamethoxam to bumble bees, honey bees and leafcutter bees, the three most common bee species managed for pollination. In acute toxicity studies, late-onset symptoms, such as ataxia, were recorded as non-lethal endpoints for all three bee species. Clothianidin and thiamethoxam produced biphasic dose-response curves for all three bee species. Clothianidin and thiamethoxam were extremely toxic to winter worker honey bees prior to brood production in spring, making this the most sensitive bee stage identified to date. Chronic exposure to field-realistic levels of neonicotinoids reduced bee survival and caused significant late-onset symptoms for all three bee species. Given these findings, neonicotinoid risk should be reevaluated to address the EDC-like behavior and the sensitivity of winter worker honey bees. Abstract Accumulating evidence suggests that neonicotinoids may have long-term adverse effects on bee health, yet our understanding of how this could occur is incomplete. Pesticides can act as endocrine disrupting chemicals (EDCs) in animals providing characteristic multiphasic dose-response curves and non-lethal endpoints in toxicity studies. However, it is not known if neonicotinoids act as EDCs in bees. To address this issue, we performed oral acute and chronic toxicity studies including concentrations recorded in nectar and pollen, applying acetamiprid, clothianidin, imidacloprid, and thiamethoxam to bumble bees, honey bees and leafcutter bees, the three most common bee species managed for pollination. In acute toxicity studies, late-onset symptoms, such as ataxia, were recorded as non-lethal endpoints for all three bee species. Clothianidin and thiamethoxam produced biphasic dose-response curves for all three bee species. Clothianidin and thiamethoxam were extremely toxic to winter worker honey bees prior to brood production in spring, making this the most sensitive bee stage identified to date. Chronic exposure to field-realistic levels of neonicotinoids reduced bee survival and caused significant late-onset symptoms for all three bee species. Given these findings, neonicotinoid risk should be reevaluated to address the EDC-like behavior and the sensitivity of winter worker honey bees. |
ArticleNumber | 10979 |
Author | Wilton, Emily de Gorter, Michael Pawluk, Abbe Baines, Danica Chomistek, Nora |
Author_xml | – sequence: 1 givenname: Danica surname: Baines fullname: Baines, Danica email: danica.baines@agr.gc.ca organization: Agriculture and Agri-Food Canada, Lethbridge Research and Development Centre – sequence: 2 givenname: Emily surname: Wilton fullname: Wilton, Emily organization: Agriculture and Agri-Food Canada, Lethbridge Research and Development Centre – sequence: 3 givenname: Abbe surname: Pawluk fullname: Pawluk, Abbe organization: Agriculture and Agri-Food Canada, Lethbridge Research and Development Centre – sequence: 4 givenname: Michael surname: de Gorter fullname: de Gorter, Michael organization: Agriculture and Agri-Food Canada, Lethbridge Research and Development Centre – sequence: 5 givenname: Nora surname: Chomistek fullname: Chomistek, Nora organization: Agriculture and Agri-Food Canada, Lethbridge Research and Development Centre |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28887455$$D View this record in MEDLINE/PubMed |
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Snippet | Accumulating evidence suggests that neonicotinoids may have long-term adverse effects on bee health, yet our understanding of how this could occur is... Abstract Accumulating evidence suggests that neonicotinoids may have long-term adverse effects on bee health, yet our understanding of how this could occur is... |
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SubjectTerms | 631/601 631/601/1466 64 Acute toxicity Apis mellifera Ataxia Bees Chronic exposure Chronic toxicity Endocrine disruptors Honey Humanities and Social Sciences Imidacloprid Insecticides multidisciplinary Nectar Pesticides Pollen Pollination Science Science (multidisciplinary) Species Thiamethoxam Toxicity Winter |
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Title | Neonicotinoids act like endocrine disrupting chemicals in newly-emerged bees and winter bees |
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