Usefulness of Intermediate Amino-Terminal Pro-Brain Natriuretic Peptide Concentrations for Diagnosis and Prognosis of Acute Heart Failure

• Published in: The American journal of cardiology Vol. 98; no. 3; pp. 386 - 390
• Main Authors: van Kimmenade, Roland R.J., Pinto, Yigal M., Bayes-Genis, Antoni, Lainchbury, John G., Richards, A. Mark, Januzzi, James L.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.08.2006; Elsevier; Elsevier Limited
• Subjects: Acute Disease; Aged; Biological and medical sciences; Biomarkers - blood; Cardiology. Vascular system; Female; Follow-Up Studies; Heart; Heart failure; Heart Failure - blood; Heart Failure - diagnosis; Heart Failure - mortality; Heart failure, cardiogenic pulmonary edema, cardiac enlargement; Humans; Male; Medical diagnosis; Medical prognosis; Medical sciences; Middle Aged; Mortality; Multivariate analysis; Natriuretic Peptide, Brain - blood; Odds Ratio; Peptide Fragments - blood; Peptides; Prognosis; Prospective Studies; Protein Precursors; Severity of Illness Index; Survival Rate; Heart failure; Brain natriuretic peptide; Prognosis; Heart disease; Acute; Cardiovascular disease; Circulatory system; Concentration; Diagnosis; Cardiology; Phlebology; Aminoacid sequence

Age-stratified cutpoints for aminoterminal pro-brain natriuretic peptide (NT–pro-BNP) concentrations are diagnostic in 83% of all subjects with acute dyspnea. This study analyzed subjects with NT–pro-BNP concentrations between the “rule-out” and “rule-in” cutpoints, the so-called natriuretic peptide...