Proteome-wide profiling and mapping of post translational modifications in human hearts

• Published in: Scientific reports Vol. 11; no. 1; p. 2184
• Main Authors: Bagwan, Navratan, El Ali, Henrik H., Lundby, Alicia
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.01.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114/2784; 631/114/663; 631/1647/296; 631/337/458; 631/337/458/1275; 631/337/458/1524; 631/337/458/1648; 631/337/458/1733; 631/337/458/2133; 631/337/458/2288; 631/337/458/2386; 631/337/458/582; 631/337/475; 631/45/475; 631/92/611; Amino acids; Glycosylation; Heart; Humanities and Social Sciences; Kinases; Mass spectrometry; Mass spectroscopy; multidisciplinary; Phosphorylation; Proteins; Proteomes; Science; Science (multidisciplinary); Translation

Post translational modifications (PTMs) are covalent modifications of proteins that can range from small chemical modifications to addition of entire proteins. PTMs contribute to regulation of protein function and thereby greatly increase the functional diversity of the proteome. In the heart, a few...