Natural killer cell awakening: unleash cancer-immunity cycle against glioblastoma

• Published in: Cell death & disease Vol. 13; no. 7; pp. 588 - 10
• Main Authors: Wang, Minjie, Zhou, Zijie, Wang, Xuan, Zhang, Chaocai, Jiang, Xiaobing
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 08.07.2022; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/250; 631/67; Adaptive Immunity; Antibodies; Autoimmune diseases; Biochemistry; Biomedical and Life Sciences; Brain cancer; Cancer; Cell activation; Cell Biology; Cell Culture; Clinical trials; Glioblastoma; Glioblastoma - pathology; Humans; Immunology; Immunoregulation; Immunotherapy; Immunotherapy - methods; Immunotherapy, Adoptive - methods; Killer Cells, Natural - metabolism; Life Sciences; Lymphocytes T; Microenvironments; Natural killer cells; Neoplasms - metabolism; Review; Review Article; Tumor Microenvironment

Due to the negligence of the complex tumor immune microenvironment, traditional treatment for glioblastoma has reached its limitation and cannot achieve a satisfying outcome in the past decade. The emergence of immunotherapy based on the theory of cancer-immunity cycle has brought a new dawn to glio...