Establishment of a striped catfish skin explant model for studying the skin response in Aeromonas hydrophila infections

• Published in: Scientific reports Vol. 11; no. 1; pp. 19057 - 13
• Main Authors: Siao, Ru-Fang, Lin, Chia-Hsuan, Chen, Li-Hsuan, Wang, Liang-Chun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.09.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/1647/767/2202; 631/326/41/2533; 631/326/41/2535; 631/601/2722; Aeromonas hydrophila; Aeromonas hydrophila - pathogenicity; Animals; Aquaculture; Catfishes; Cell culture; Epithelial cells; Fish Diseases - immunology; Fish Diseases - microbiology; Fish Diseases - pathology; Gram-Negative Bacterial Infections - immunology; Gram-Negative Bacterial Infections - microbiology; Gram-Negative Bacterial Infections - pathology; Humanities and Social Sciences; Infections; Inoculation; multidisciplinary; Pathogens; Science; Science (multidisciplinary); Skin; Skin - immunology; Tissue culture

Teleost fish skin serves as the first line of defense against pathogens. The interaction between pathogen and host skin determines the infection outcome. However, the mechanism(s) that modulate infection remain largely unknown. A proper tissue culture model that is easier to handle but can quantitat...