Bsep expression in hilar cholangiocarcinoma of rat model

• Published in: Scientific reports Vol. 11; no. 1; pp. 2861 - 7
• Main Authors: Zhang, Meng-yu, Wang, Jie-ping, He, Kai, Xia, Xian-ming
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 03.02.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/67/70; 692/699/67; Anesthesia; Animal models; Bile; Bile ducts; Bilirubin; Body mass; Body weight; Cholangiocarcinoma; Cholesterol; Diet; Drug delivery; Drug development; Gene therapy; Glyceraldehyde-3-phosphate dehydrogenase; Humanities and Social Sciences; Light microscopy; mRNA; multidisciplinary; Polymerase chain reaction; Rodents; Science; Science (multidisciplinary); Statistical analysis

Develop a rat model of hilar cholangiocarcinoma for detecting bile salt export pump ( Bsep ) expression in hilar cholangiocarcinoma tissues, in order to provide a new therapeutic target for the gene therapy of hilar cholangiocarcinoma. Sixty male Wistar rats (body weight, 190 ± 8 g) were randomly di...