Compare the effectiveness of extracorporeal shockwave and hyperbaric oxygen therapy on enhancing wound healing in a streptozotocin‐induced diabetic rodent model

• Published in: The Kaohsiung journal of medical sciences Vol. 39; no. 11; pp. 1135 - 1144
• Main Authors: Chen, Rong‐Fu, Lin, Yun‐Nan, Liu, Keng‐Fan, Lee, Chia‐Chun, Hu, Chieh‐Ju, Wang, Chun‐Ting, Wang, Ching‐Jen, Kuo, Yur‐Ren
• Format: Journal Article
• Language: English
• Published: China (Republic : 1949- ) John Wiley & Sons, Inc 01.11.2023; Wiley Publishing Asia Pty Ltd; Wiley
• Subjects: Analysis; Angiogenesis; Animals; Antibodies; Biopsy; Care and treatment; Clinical trials; Diabetes; Diabetes Mellitus, Experimental - therapy; Diabetic Foot - diagnosis; Diabetic Foot - pathology; Diabetic Foot - therapy; diabetic foot ulcers; diabetic wound healing; Endothelium; extracorporeal shock‐wave therapy; Foot diseases; Glucose; Growth factors; High-Energy Shock Waves; hyperbaric oxygen therapy; Hyperbaric Oxygenation; Ki-67 Antigen; Laboratory animals; Leg ulcers; Neovascularization; Neovascularization, Pathologic; Nitric oxide; Original; Oxygen therapy; Performance evaluation; Rodentia - metabolism; Rodents; Skin; Streptozocin; Streptozocin - pharmacology; streptozotocin; Vascular endothelial growth factor; Vascular Endothelial Growth Factor A - genetics; Vascular Endothelial Growth Factor A - metabolism; Wound healing; Wound Healing - physiology; Wounds and injuries; Germany; Taiwan; diabetic foot ulcers; hyperbaric oxygen therapy; streptozotocin; extracorporeal shock-wave therapy; diabetic wound healing

Studies have revealed that both extracorporeal shock‐wave therapy (ESWT) and hyperbaric oxygen therapy (HBOT) can accelerate wound healing. This study aimed to compare the effectiveness of ESWT and HBOT in enhancing diabetic wound healing. A dorsal skin defect in a streptozotocin‐induced diabetes ro...