TAZ promotes osteogenic differentiation of mesenchymal stem cells line C3H10T1/2, murine multi-lineage cells lines C2C12, and MEFs induced by BMP9

• Published in: Cell death discovery Vol. 8; no. 1; pp. 499 - 12
• Main Authors: Huang, Huakun, Lu, Qiuping, Ye, Caihong, Wei, Mengqi, Yang, Chunmei, Zhang, Lulu, Huang, Yanran, Luo, Xiaoji, Luo, Jinyong
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 27.12.2022; Springer Nature B.V; Nature Publishing Group
• Subjects: 631/532/2074; 631/80/86/2364; Apoptosis; Biochemistry; Biomedical and Life Sciences; Bone growth; Bone morphogenetic protein 9; Cell Biology; Cell Cycle Analysis; Cell differentiation; Cell lines; Cell proliferation; Cell self-renewal; Life Sciences; Mesenchymal stem cells; Nuclear transport; Ossification (ectopic); Osteogenesis; Phosphorylation; Stem cell transplantation; Stem Cells; β-Catenin

Bone morphogenetic protein 9 (BMP9), also named as growth differentiation factor 2 (GDF-2), is the strongest cytokine that promotes osteogenic differentiation in the BMP family, and has broad clinical application value. Nevertheless, the mechanism of BMP9 promotes osteogenic differentiation remain u...