Low Bilirubin Levels Indicate a High Risk of Cerebral Deep White Matter Lesions in Apparently Healthy Subjects

• Published in: Scientific reports Vol. 8; no. 1; pp. 6473 - 5
• Main Authors: Higuchi, Satoshi, Kabeya, Yusuke, Uchida, Junko, Kato, Kiyoe, Tsukada, Nobuhiro
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.04.2018; Nature Publishing Group
• Subjects: 692/617/375/132; 692/617/375/1370; Antioxidants; Arteriosclerosis; Bilirubin; Blood pressure; Cerebrovascular diseases; Cholesterol; Cognitive ability; Confidence intervals; Hemoglobin; Humanities and Social Sciences; Internal medicine; Laboratories; Lesions; Lipoproteins; Magnetic resonance imaging; Medicine; multidisciplinary; Regression analysis; Science; Science (multidisciplinary); Substantia alba; Uric acid; Vascular diseases

Recent studies have reported that deep white matter lesions (DWMLs) on magnetic resonance imaging scans are related to the risk of developing impaired cognitive function in future. Bilirubin exhibits a potent antioxidant effect and an inverse relationship has been reported between bilirubin levels a...