Identification of poly(ADP-ribose) polymerase 9 (PARP9) as a noncanonical sensor for RNA virus in dendritic cells - Xing, Junji; Zhang, Ao; Du, Yong; Fang, Mingli; Minze, Laurie J.; Liu, Yong-Jun; Li, Xian Chang; Zhang, Zhiqiang (Nature communications, 2021)
Keywords: 1-Phosphatidylinositol 3-kinase; 13/1; 13/21; 13/31; 13/95; 14/19; 38/109; 38/91; 631/250; 631/250/262/2106; 64/60; 692/420/254; 692/699/255/2514; 82/80; 96/109; Adenosine diphosphate; Animals; Antiviral drugs; Chlorocebus aethiops; Dendritic cells; Dendritic Cells - enzymology; Dendritic Cells - virology; Humanities and Social Sciences; Humans; Immune system; Infections; Interferon; Interferon regulatory factor 3; Interferon regulatory factor 7; Interferon Regulatory Factor-3 - metabolism; Interferon Regulatory Factor-7 - metabolism; Interferon Type I - metabolism; Kinases; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mitochondria; multidisciplinary; Neoplasm Proteins - genetics; Neoplasm Proteins - metabolism; Nucleic acids; Phosphatidylinositol 3-Kinases - metabolism; Phosphorylation; Poly(ADP-ribose); Poly(ADP-ribose) polymerase; Poly(ADP-ribose) Polymerases - genetics; Poly(ADP-ribose) Polymerases - metabolism; Proto-Oncogene Proteins c-akt - metabolism; Ribonucleic acid; Ribose; RNA; RNA Virus Infections - enzymology; RNA Virus Infections - virology; RNA viruses; RNA Viruses - genetics; RNA Viruses - physiology; RNA, Viral - metabolism; Science; Science (multidisciplinary); Sensors; Signal Transduction; THP-1 Cells; Vero Cells; Viral infections; Viruses