A population-specific HTR2B stop codon predisposes to severe impulsivity - Bevilacqua, Laura; Doly, Stéphane; Kaprio, Jaakko; Yuan, Qiaoping; Tikkanen, Roope; Paunio, Tiina; Zhou, Zhifeng; Wedenoja, Juho; Maroteaux, Luc; Diaz, Silvina; Belmer, Arnaud; Hodgkinson, Colin A.; et al. (Nature (London), 2010)
Keywords: 631/208/727/2000; 692/1807; 692/699/476; Aggressive behavior; Animals; Behavior; Biochemistry, Molecular Biology; Biological and medical sciences; Brain - metabolism; Case-Control Studies; Cell Line; Female; Finland; Founder Effect; Fundamental and applied biological sciences. Psychology; Gene expression; Gene Expression Regulation; Gene Knockout Techniques; Genetics of eukaryotes. Biological and molecular evolution; Genotype; Genotype & phenotype; Human; Humanities and Social Sciences; Humans; Impulsive Behavior - genetics; Life Sciences; Male; Mental Disorders - genetics; Mice; Mice, 129 Strain; Mice, Knockout; multidisciplinary; Neurological disorders; Neurology; Neurotransmitters; Pedigree; Polymorphism, Single Nucleotide - genetics; Population genetics, reproduction patterns; Receptor, Serotonin, 5-HT2B - genetics; Receptor, Serotonin, 5-HT2B - metabolism; Science; Science (multidisciplinary); Testosterone - blood; Testosterone - cerebrospinal fluid; Violence; Finland; Human; Impulsivity; Founder effect; Severe; Nonsense mutation; Population genetics