Vitamin D, Autoimmune Disease and Rheumatoid Arthritis
Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH) 2 D3). The nuclear vit...
Saved in:
| Published in | Calcified tissue international Vol. 106; no. 1; pp. 58 - 75 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer US
01.01.2020
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH)
2
D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH)
2
D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH)
2
D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment. |
|---|---|
| AbstractList | Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH)2D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH)2D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment.Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH)2D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH)2D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment. Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH) 2 D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH) 2 D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH) 2 D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment. Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH)2D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH)2D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment. Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent amongst these are the potent immunomodulatory effects of the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-(OH) D3). The nuclear vitamin D receptor (VDR) for 1,25-(OH) D3 is expressed by many cells within the immune system and resulting effects include modulation of T cell phenotype to suppress pro-inflammatory Th1 and Th17 CD4+ T cells and promote tolerogenic regulatory T cells. In addition, antigen-presenting cells have been shown to express the enzyme 1α-hydroxylase that converts precursor 25-hydroxyvitamin D3 (25-OHD3) to 1,25-(OH) D3, so that immune microenvironments are able to both activate and respond to vitamin D. As a consequence of this local, intracrine, system, immune responses may vary according to the availability of 25-OHD3, and vitamin D deficiency has been linked to various autoimmune disorders including rheumatoid arthritis (RA). The aim of this review is to explore the immune activities of vitamin D that impact autoimmune disease, with specific reference to RA. As well as outlining the mechanisms linking vitamin D with autoimmune disease, the review will also describe the different studies that have linked vitamin D status to RA, and the current supplementation studies that have explored the potential benefits of vitamin D for prevention or treatment of RA. The overall aim of the review is to provide a fresh perspective on the potential role of vitamin D in RA pathogenesis and treatment. |
| Author | Li, Danyang Raza, Karim Jeffery, Louisa E. Hewison, Martin Harrison, Stephanie R. |
| Author_xml | – sequence: 1 givenname: Stephanie R. surname: Harrison fullname: Harrison, Stephanie R. organization: Institute of Metabolism and Systems Research, The University of Birmingham, Department of Rheumatology, Sandwell and West, Birmingham Hospitals NHS Trust – sequence: 2 givenname: Danyang surname: Li fullname: Li, Danyang organization: Institute of Metabolism and Systems Research, The University of Birmingham – sequence: 3 givenname: Louisa E. surname: Jeffery fullname: Jeffery, Louisa E. organization: Institute of Translation Medicine, The University of Birmingham – sequence: 4 givenname: Karim surname: Raza fullname: Raza, Karim organization: Department of Rheumatology, Sandwell and West, Birmingham Hospitals NHS Trust, Institute of Inflammation and Ageing, Arthritis Research UK Rheumatoid Arthritis Pathogenesis Centre of Excellence and MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, University of Birmingham – sequence: 5 givenname: Martin orcidid: 0000-0001-5806-9690 surname: Hewison fullname: Hewison, Martin email: m.hewison@bham.ac.uk organization: Institute of Metabolism and Systems Research, The University of Birmingham, Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31286174$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kUFrFTEUhYO02NfqH3AhA266cOq9SSaZbIRHq22hIIiKu5DJZPpSZpKazAj-e_N8rdYuugrhfudw7j2HZC_E4Ah5hXCCAPJdBqCU1YCqBmikrOkzskLOaA0tlXtkBSixVkJ-PyCHOd8AIBdCPCcHDGkrUPIVEd_8bCYfqrO31XqZo5-mJbjqzGdnsqtM6KvPG7dMpoz6ap3mTfKzzy_I_mDG7F7evUfk68cPX04v6qtP55en66vaNhzmGtkge8o70Q_D0CpgivasdX1rqBwoc1RA-SNSK5kSnWy6FoVtLLdMKdZRdkTe73xvl25yvXVhTmbUt8lPJv3S0Xj9_yT4jb6OP7VQAigTxeD4ziDFH4vLs558tm4cTXBxyZrShjeouOAFffMIvYlLCmW9LcUER6GwUK8fJvob5f6kBWh3gE0x5-QGbcuJZx-3Af2oEfS2Pb1rT5f29J_29HZb-kh67_6kiO1EucDh2qV_sZ9Q_Qaa0qp8 |
| CitedBy_id | crossref_primary_10_1016_j_eclinm_2023_101957 crossref_primary_10_4082_kjfm_20_0181 crossref_primary_10_1155_2022_5268706 crossref_primary_10_1016_j_jsbmb_2024_106663 crossref_primary_10_3390_biom13040709 crossref_primary_10_1016_j_heliyon_2025_e42463 crossref_primary_10_1186_s13293_021_00358_3 crossref_primary_10_3390_nu15143174 crossref_primary_10_4103_tmj_tmj_2_23 crossref_primary_10_1111_jog_16151 crossref_primary_10_5114_reum_187391 crossref_primary_10_3390_immuno1040037 crossref_primary_10_1016_j_jpba_2023_115908 crossref_primary_10_36740_Merkur202402110 crossref_primary_10_3390_ijms23031410 crossref_primary_10_3389_fimmu_2021_754056 crossref_primary_10_1007_s00253_024_13244_w crossref_primary_10_1016_j_jbo_2020_100329 crossref_primary_10_1002_slct_202402035 crossref_primary_10_1177_20503121241283335 crossref_primary_10_1007_s00592_024_02292_3 crossref_primary_10_1016_j_jsbmb_2025_106710 crossref_primary_10_3390_nu14030447 crossref_primary_10_1111_febs_15312 crossref_primary_10_15388_Amed_2021_29_1_7 crossref_primary_10_3390_pathogens12091180 crossref_primary_10_1016_j_bjorl_2024_101500 crossref_primary_10_1016_j_jaut_2024_103294 crossref_primary_10_3389_fneur_2021_604052 crossref_primary_10_21518_ms2024_007 crossref_primary_10_3389_fimmu_2024_1425119 crossref_primary_10_3390_nu16091358 crossref_primary_10_1080_20002297_2024_2348260 crossref_primary_10_3389_fendo_2024_1360525 crossref_primary_10_2174_0118715230264101230925060355 crossref_primary_10_31146_1682_8658_ecg_203_7_192_203 crossref_primary_10_7759_cureus_72486 crossref_primary_10_1530_EC_21_0554 crossref_primary_10_2174_1574885516666210719092931 crossref_primary_10_3892_ijmm_2024_5471 crossref_primary_10_1007_s00403_024_03443_w crossref_primary_10_1002_iid3_676 crossref_primary_10_1080_03639045_2023_2301478 crossref_primary_10_11005_jbm_2023_30_3_219 crossref_primary_10_3389_fimmu_2021_767512 crossref_primary_10_38025_2078_1962_2021_20_5_92_98 crossref_primary_10_5937_arhfarm73_46395 crossref_primary_10_3390_diagnostics14182035 crossref_primary_10_1155_2022_8689777 crossref_primary_10_1007_s12011_023_03636_w crossref_primary_10_1007_s40265_023_01875_8 crossref_primary_10_1186_s43166_020_00042_1 crossref_primary_10_1186_s12865_024_00672_6 crossref_primary_10_1021_acsabm_4c01139 crossref_primary_10_1371_journal_pone_0242230 crossref_primary_10_1186_s12887_022_03297_z crossref_primary_10_3390_nu16152388 crossref_primary_10_36740_WLek202107111 crossref_primary_10_15789_1563_0625_IEO_2176 crossref_primary_10_1016_j_genrep_2022_101591 crossref_primary_10_3389_fmed_2022_972586 crossref_primary_10_1016_j_jsps_2024_102137 crossref_primary_10_1016_j_nut_2020_110964 crossref_primary_10_1016_j_envres_2021_112168 crossref_primary_10_3389_fphar_2022_902639 crossref_primary_10_3390_nu12051456 crossref_primary_10_1038_s41598_019_53864_1 crossref_primary_10_1080_17469899_2020_1723416 crossref_primary_10_3389_fimmu_2020_616483 crossref_primary_10_3389_fimmu_2023_950465 crossref_primary_10_1007_s00223_019_00650_w crossref_primary_10_46903_gjms_18_03_841 crossref_primary_10_1016_j_imlet_2024_106890 crossref_primary_10_1038_s42003_021_01943_3 crossref_primary_10_3390_cancers12102965 crossref_primary_10_3390_medicina57040346 crossref_primary_10_1016_j_jpsychires_2020_02_027 crossref_primary_10_32628_IJSRST207473 crossref_primary_10_3390_nu15061349 crossref_primary_10_1080_08923973_2023_2239490 crossref_primary_10_1186_s41927_020_00134_7 crossref_primary_10_1371_journal_pone_0295288 crossref_primary_10_3389_fmicb_2022_965709 crossref_primary_10_1007_s41894_024_00143_6 crossref_primary_10_7759_cureus_34815 crossref_primary_10_1038_s41598_020_66945_3 crossref_primary_10_3390_jcm13237212 crossref_primary_10_15789_1563_0625_CAI_2685 crossref_primary_10_1186_s12964_024_01779_4 crossref_primary_10_3233_JIFS_231537 crossref_primary_10_1016_j_ijid_2021_04_083 crossref_primary_10_1038_s41598_025_92014_8 crossref_primary_10_3389_fimmu_2020_596611 crossref_primary_10_1155_2022_1926661 crossref_primary_10_3390_nu14030402 crossref_primary_10_52420_2071_5943_2022_21_5_41_50 crossref_primary_10_3390_ijms23169164 crossref_primary_10_3390_nu12092788 crossref_primary_10_4103_MJBL_MJBL_199_23 crossref_primary_10_1210_clinem_dgae290 crossref_primary_10_1128_msphere_01039_24 crossref_primary_10_1111_1348_0421_12923 crossref_primary_10_1371_journal_pone_0271008 crossref_primary_10_1002_cbf_70037 crossref_primary_10_3390_medicina58050585 crossref_primary_10_6118_jmm_21011 crossref_primary_10_1002_brb3_1892 crossref_primary_10_1016_j_genrep_2022_101561 crossref_primary_10_1186_s12883_024_03687_z crossref_primary_10_1186_s41927_023_00325_y crossref_primary_10_3389_fimmu_2023_1223810 crossref_primary_10_1038_s41598_024_67588_4 crossref_primary_10_2174_0118715303257269231011073100 crossref_primary_10_4103_ajim_ajim_89_22 crossref_primary_10_3390_nu16183215 crossref_primary_10_1016_j_carbpol_2021_117948 crossref_primary_10_3390_ijms24076154 crossref_primary_10_3390_ijms26062555 crossref_primary_10_3389_fimmu_2023_1137538 crossref_primary_10_1007_s10565_021_09647_4 crossref_primary_10_33262_anatomiadigital_v7i4_1_3045 crossref_primary_10_54393_pbmj_v5i6_575 crossref_primary_10_1186_s12964_022_00953_w crossref_primary_10_29058_mjwbs_1109540 crossref_primary_10_1007_s12026_022_09324_6 crossref_primary_10_3390_jcm13040973 crossref_primary_10_3390_biomedicines11040994 crossref_primary_10_3390_ijms24043394 crossref_primary_10_3390_life14050617 crossref_primary_10_3390_nu15030533 crossref_primary_10_56294_saludcyt2023307 crossref_primary_10_4251_wjgo_v16_i6_2394 crossref_primary_10_1186_s13075_023_03159_8 crossref_primary_10_3390_nu14081538 crossref_primary_10_3892_etm_2022_11214 |
| Cites_doi | 10.1016/j.jsbmb.2013.09.012 10.1677/jme.0.0250141 10.1016/j.jsbmb.2006.12.078 10.1210/jcem-57-6-1308 10.1097/MIB.0000000000000016 10.3389/fimmu.2018.01622 10.1007/s12031-018-1034-1 10.1093/rheumatology/keu323 10.1007/s12026-014-8579-z 10.1016/j.abb.2012.04.001 10.1002/eji.200425995 10.1371/journal.pmed.1001866 10.1016/j.imlet.2013.08.012 10.4049/jimmunol.0803217 10.1210/jc.2010-0195 10.1016/j.mce.2010.02.013 10.4103/0256-4947.72265 10.1016/j.mce.2003.11.017 10.4049/jimmunol.1000695 10.3109/10408363.2015.1094443 10.1210/me.2003-0281 10.1073/pnas.1315006110 10.1007/s10067-012-2080-7 10.1111/imm.12610 10.1111/cei.12870 10.1002/jbmr.5650060711 10.4049/jimmunol.1500306 10.1007/s10067-012-2154-6 10.1016/j.jsbmb.2013.12.009 10.1007/s11606-016-3645-y 10.1177/1352458516654310 10.1172/JCI65842 10.1136/bmj.k1036 10.1136/bmj.i6583 10.4049/jimmunol.179.3.1634 10.1371/journal.pone.0146351 10.1007/s00415-015-7902-5 10.4049/jimmunol.136.8.2734 10.1101/gr.107920.110 10.1016/j.clnu.2013.01.012 10.1016/j.diabres.2015.01.036 10.1007/s40629-018-0054-2 10.1016/j.jsbmb.2004.03.095 10.1016/j.intimp.2007.09.016 10.1002/jcb.10347 10.1016/0008-8749(89)90381-X 10.2337/dc09-2297 10.1002/art.30093 10.1210/jc.2014-1389 10.1097/BOR.0000000000000498 10.1007/s10067-017-3870-8 10.1016/j.autrev.2009.11.019 10.1080/08830185.2018.1465943 10.3390/ijerph15081726 10.1177/0961203316682095 10.4049/jimmunol.167.9.4974 10.1136/annrheumdis-2014-207137 10.1016/0162-3109(91)90015-Q 10.1002/brb3.761 10.1016/j.abb.2011.11.003 10.4049/jimmunol.164.9.4443 10.1073/pnas.121172198 10.2337/dc10-0814 10.3390/nu7043011 10.1016/j.msard.2018.01.002 10.1002/art.39108 10.1016/j.jneuroim.2017.11.007 10.1093/rheumatology/keu420 10.4103/1735-1995.199089 10.1182/blood-2002-11-3521 10.4049/jimmunol.164.5.2405 10.1136/annrheumdis-2013-204749 10.1111/nyas.12129 10.1038/ncpendmet0716 10.1093/jn/nxy116 10.1038/cddis.2016.300 10.1196/annals.1375.050 10.1002/dmrr.977 10.1136/ard.51.2.220 10.1177/1753425917721965 10.1038/cmi.2010.73 10.1007/BF00403372 10.1186/ar12 10.1136/ard.48.9.723 10.1038/srep10642 10.1177/1352458517737373 10.1186/1741-7015-10-69 10.1001/archpediatrics.2012.164 10.1210/en.2010-0089 10.4049/jimmunol.170.11.5382 10.1097/MD.0000000000007024 10.2337/db07-0652 10.1128/MCB.05020-11 10.1016/j.jsbmb.2018.10.008 10.1016/j.jaut.2017.10.001 10.1177/0961203307085879 10.1007/s11926-013-0352-0 10.1136/ard.54.12.944 10.1073/pnas.1003852107 10.1007/s10067-013-2174-x 10.1210/en.2017-00748 10.1074/jbc.C109.071225 10.1371/journal.pone.0005810 10.1371/journal.pone.0131539 10.1182/blood.V82.4.1300.1300 10.2337/db10-1656 10.1186/s12891-015-0505-6 10.1073/pnas.0711558105 10.1007/s00281-017-0620-6 10.1056/NEJMoa1103864 10.1186/ar4545 10.1126/science.1123933 10.1111/j.1365-2249.2009.03961.x 10.1084/jem.20011629 10.4049/jimmunol.1200786 10.1002/art.27756 10.1210/en.2008-0060 10.1681/ASN.2013040355 10.1038/ni.1851 10.1177/0961203317716321 10.1155/2013/160123 10.4049/jimmunol.180.5.2786 10.1136/ard.2007.072736 10.1136/gutjnl-2013-304907.038 10.4049/jimmunol.156.8.2674 10.1016/j.abb.2011.11.001 10.1016/B978-0-12-386960-9.00002-2 10.1007/s10067-013-2216-4 10.2174/1568026611313060004 10.1210/er.2008-0004 10.1136/annrheumdis-2011-200424 10.1038/nrrheum.2015.140 10.1371/journal.pone.0109194 10.14715/cmb/2018.64.1.2 10.1016/j.crohns.2013.01.012 10.1002/acr.22621 10.1016/j.tem.2005.06.004 10.1016/j.jaut.2004.06.004 10.1001/jama.2010.594 10.1002/eji.200838216 10.1136/annrheumdis-2013-203566 10.1017/S0029665111001650 10.4049/jimmunol.0803345 10.1136/annrheumdis-2013-204228 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2019 Calcified Tissue International is a copyright of Springer, (2019). All Rights Reserved. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: The Author(s) 2019 – notice: Calcified Tissue International is a copyright of Springer, (2019). All Rights Reserved. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7QP 7RV 7X7 7XB 88E 8AO 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. KB0 LK8 M0S M1P M7P NAPCQ PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS 7X8 5PM |
| DOI | 10.1007/s00223-019-00577-2 |
| DatabaseName | Springer Nature OA Free Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Calcium & Calcified Tissue Abstracts Nursing & Allied Health Database Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Biological Sciences Health & Medical Collection (Alumni) Medical Database Biological Science Database Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Pharma Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Biological Science Collection ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic Calcium & Calcified Tissue Abstracts ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic CrossRef ProQuest Central Student MEDLINE |
| Database_xml | – sequence: 1 dbid: C6C name: Springer Nature OA Free Journals url: http://www.springeropen.com/ sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Anatomy & Physiology |
| EISSN | 1432-0827 |
| EndPage | 75 |
| ExternalDocumentID | PMC6960236 31286174 10_1007_s00223_019_00577_2 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Review |
| GrantInformation_xml | – fundername: Royal Society grantid: WM130118 – fundername: Medical Research Council grantid: PhD Studentship – fundername: National Institutes of Health Research grantid: Birmingham Biomedical Research Centre – fundername: Medical Research Council grantid: MR/P021220/1 – fundername: ; grantid: Birmingham Biomedical Research Centre – fundername: ; grantid: WM130118 – fundername: ; grantid: PhD Studentship |
| GroupedDBID | --- -4W -56 -5G -BR -EM -Y2 -~C .55 .86 .VR 06C 06D 0R~ 0VY 199 1N0 2.D 203 23N 28- 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 36B 3O- 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5RE 5VS 67Z 6NX 78A 7RV 7X7 88E 8AO 8FE 8FH 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAWTL AAYIU AAYQN AAYTO AAYZH ABAKF ABBBX ABBXA ABDZT ABECU ABFTV ABHLI ABHQN ABIPD ABJNI ABJOX ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABQBU ABQSL ABSXP ABTEG ABTHY ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACAOD ACBXY ACDTI ACGFS ACHSB ACHXU ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACZOJ ADBBV ADHIR ADIMF ADINQ ADJJI ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADYPR ADZKW AEBTG AEFIE AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFEXP AFFNX AFKRA AFLOW AFQWF AFWTZ AFZKB AGAYW AGDGC AGGDS AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BBNVY BBWZM BDATZ BENPR BGNMA BHPHI BKEYQ BPHCQ BSONS BVXVI C6C CAG CCPQU COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP EBD EBLON EBS EIOEI EJD EMB EMOBN EN4 ESBYG EX3 F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GXS H13 HCIFZ HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IHE IJ- IKXTQ IMOTQ ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH L7B LAS LK8 LLZTM M1P M4Y M7P MA- N2Q NAPCQ NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM P19 P2P P9S PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOK QOR QOS R89 R9I RHV RIG RNI RNS ROL RPX RRX RSV RZK S16 S1Z S26 S27 S28 S37 S3B SAP SBL SBY SCLPG SDH SDM SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZN T13 T16 TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 WOW X7M YLTOR Z45 Z7U Z7V Z7W Z82 Z87 Z8O Z8P Z8Q Z8V Z91 ZGI ZMTXR ZOVNA ~02 ~EX AAPKM AAYXX ABBRH ABDBE ABFSG ACSTC AEZWR AFDZB AFHIU AFOHR AGQPQ AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT ABRTQ CGR CUY CVF ECM EIF NPM PJZUB PPXIY PQGLB 7QP 7XB 8FK AZQEC DWQXO GNUQQ K9. PKEHL PQEST PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c540t-13f7d24b6dfff890392d38ed8a27f23e260d38112c7396b75b816c5c4c3993b23 |
| IEDL.DBID | U2A |
| ISSN | 0171-967X 1432-0827 |
| IngestDate | Thu Aug 21 14:35:17 EDT 2025 Fri Jul 11 01:41:40 EDT 2025 Fri Jul 25 19:25:35 EDT 2025 Mon Jul 21 06:02:58 EDT 2025 Tue Jul 01 00:22:34 EDT 2025 Thu Apr 24 23:08:20 EDT 2025 Fri Feb 21 02:44:37 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Autoimmune disease Inflammation Vitamin D Vitamin D receptor Rheumatoid arthritis T cell |
| Language | English |
| License | Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c540t-13f7d24b6dfff890392d38ed8a27f23e260d38112c7396b75b816c5c4c3993b23 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 |
| ORCID | 0000-0001-5806-9690 |
| OpenAccessLink | https://link.springer.com/10.1007/s00223-019-00577-2 |
| PMID | 31286174 |
| PQID | 2253641691 |
| PQPubID | 48445 |
| PageCount | 18 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_6960236 proquest_miscellaneous_2254519464 proquest_journals_2253641691 pubmed_primary_31286174 crossref_citationtrail_10_1007_s00223_019_00577_2 crossref_primary_10_1007_s00223_019_00577_2 springer_journals_10_1007_s00223_019_00577_2 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2020-01-01 |
| PublicationDateYYYYMMDD | 2020-01-01 |
| PublicationDate_xml | – month: 01 year: 2020 text: 2020-01-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: United States |
| PublicationSubtitle | and Musculoskeletal Research |
| PublicationTitle | Calcified tissue international |
| PublicationTitleAbbrev | Calcif Tissue Int |
| PublicationTitleAlternate | Calcif Tissue Int |
| PublicationYear | 2020 |
| Publisher | Springer US Springer Nature B.V |
| Publisher_xml | – name: Springer US – name: Springer Nature B.V |
| References | DeLuca (CR2) 2014; 3 Sadeghi, Wessner, Laggner, Ploder, Tamandl, Friedl, Zugel, Steinmeyer, Pollak, Roth, Boltz-Nitulescu, Spittler (CR36) 2006; 36 Merino, Alvarez-Mon, de la Hera, Ales, Bonilla, Durantez (CR61) 1989; 118 Penna, Adorini (CR47) 2000; 164 Allan, Cranston, Lindblad, McCormack, Kolber, Garrison, Korownyk (CR133) 2016; 31 Penna, Adorini (CR41) 2000; 164 Griffin, Lutz, Phan, Bachman, McKean, Kumar (CR44) 2001; 98 Jeffery, Burke, Mura, Zheng, Qureshi, Hewison, Walker, Lammas, Raza, Sansom (CR59) 2009; 183 Anderson, Swan, Wong, Buck, Eltherington, Harry, Patterson, Pratt, Reynolds, Doran, Kirby, Isaacs, Hilkens (CR144) 2017; 187 Pedersen, Holmstrøm, Jensen, Fuchs, Rasmussen, Kvistborg, Claesson, Zocca (CR43) 2009; 157 Nikiphorou, Uksila, Sokka (CR69) 2018; 37 Zhao, Duan, Wu, Gao, Wang, Zheng (CR83) 2017; 6 Liu, Stenger, Li, Wenzel, Tan, Krutzik, Ochoa, Schauber, Wu, Meinken, Kamen, Wagner, Bals, Steinmeyer, Zugel, Gallo, Eisenberg, Hewison, Hollis, Adams, Bloom, Modlin (CR33) 2006; 311 Aranow, Kamen, Dall’Era, Massarotti, Mackay, Koumpouras, Coca, Chatham, Clowse, Criscione-Schreiber, Callahan, Goldmuntz, Keyes-Elstein, Oswald, Gregersen, Diamond (CR86) 2015; 67 Mohammad, Mayberry (CR107) 2013; 62 Rolf, Muris, Theunissen, Hupperts, Damoiseaux, Smolders (CR78) 2018; 314 Langdon, Haleagrahara (CR146) 2018; 37 Abdel Galil, El-Shafey, Abdul-Makoud, El-Boshy (CR84) 2018; 27 Liu, Nguyen, Chun, Lagishetty, Ren, Wu, Hollis, DeLuca, Adams, Hewison (CR109) 2008; 149 Mathieu (CR4) 2015; 108 Christakos, Hewison, Gardner, Wagner, Sergeev, Rutten, Pittas, Boland, Ferrucci, Bikle (CR3) 2013; 1287 Kamisli, Acar, Sozen, Tecellioglu, Yücel, Vaizoglu, Özcan (CR75) 2018; 20 Mathieu, Waer, Laureys, Rutgeerts, Bouillon (CR98) 1994; 37 Hewison, Burke, Evans, Lammas, Sansom, Liu, Modlin, Adams (CR16) 2007; 103 Cantorna, Snyder, Lin, Yang (CR54) 2015; 7 Heine, Niesner, Chang, Steinmeyer, Zugel, Zuberbier, Radbruch, Worm (CR65) 2008; 38 Chun, Peercy, Orwoll, Nielson, Adams, Hewison (CR20) 2014; 144 Bscheider, Butcher (CR143) 2016; 148 van Halteren, Tysma, van Etten, Mathieu, Roep (CR42) 2004; 23 Haga, Schmedes, Naderi, Moreno, Peen (CR122) 2013; 32 Varenna, Manara, Cantatore, Del Puente, Di Munno, Malavolta, Minisola, Adami, Sinigaglia, Rossini (CR131) 2012; 30 Sarkar, Hewison, Studzinski, Li, Kalia (CR53) 2016; 53 Mokry, Ross, Ahmad, Forgetta, Smith, Goltzman, Leong, Greenwood, Thanassoulis, Richards (CR73) 2015; 12 Costenbader, Feskanich, Holmes, Karlson, Benito-Garcia (CR88) 2008; 67 Lopez, Regulla, Pani, Krause, Usadel, Badenhoop (CR95) 2004; 89–90 Moradi, Schnatzer, Hagmann, Rosshirt, Gotterbarm, Kretzer, Thomsen, Lorenz, Zeifang, Tretter (CR150) 2014; 16 Nistala, Adams, Cambrook, Ursu, Olivito, de Jager, Evans, Cimaz, Bajaj-Elliott, Wedderburn (CR140) 2010; 107 Szeles, Keresztes, Torocsik, Balajthy, Krenacs, Poliska, Steinmeyer, Zuegel, Pruenster, Rot, Nagy (CR49) 2009; 182 Karimzadeh, Shirzadi, Karimifar (CR87) 2017; 22 Meyer, Saccone, Tugizimana, Asani, Jeffery, Bornman (CR37) 2017; 8 Miclea, Miclea, Pistor, Hoepner, Chan, Hoepner (CR79) 2017; 7 Hewison, Zehnder, Bland, Stewart (CR11) 2000; 25 Lima, Paupitz, Aikawa, Takayama, Bonfa, Pereira (CR89) 2016; 68 Hewison, Zehnder, Chakraverty, Adams (CR40) 2004; 215 Provvedini, Tsoukas, Deftos, Manolagas (CR51) 1986; 136 Joshi, Pantalena, Liu, Gaffen, Liu, Rohowsky-Kochan, Ichiyama, Yoshimura, Steinman, Christakos, Youssef (CR55) 2011; 31 Adams, Rafison, Witzel, Reyes, Shieh, Chun, Zavala, Hewison, Liu (CR19) 2014; 144 Tetlow, Woolley (CR158) 1999; 1 Kim, Lee, Kwon, Choi, Lee, Song, Sohn, Ji (CR35) 2013; 154 Li, Jeffery, Jenkinson, Harrison, Chun, Adams, Raza, Hewison (CR128) 2018; 187 Emery, Salmon (CR123) 1995; 54 Yu, Cantorna (CR62) 2008; 105 Baeke, Korf, Overbergh, Verstuyf, Thorrez, Van Lommel, Waer, Schuit, Gysemans, Mathieu (CR151) 2011; 186 Shirakawa, Nagakubo, Hieshima, Nakayama, Jin, Yoshie (CR66) 2008; 180 Hufnaql, Jensen-Jarolim (CR67) 2018; 27 Higgins, Mackie, Thalayasingam, Bingham, Hamilton, Kelly (CR118) 2013; 32 Hewison (CR26) 2011; 7 Zhu, Ochalek, Kaufmann, Jones, Deluca (CR10) 2013; 110 Křenek, Benešová, Bienertová-Vašků, Vašků (CR76) 2018; 64 Rosjo, Steffensen, Jorgensen, Lindstrom, Saltyte Benth, Michelsen, Aukrust, Ueland, Kampman, Torkildsen, Holmoy (CR81) 2015; 262 Gu, Gu, Lv, Yu, Wang, Zhou, Qiao, Mao, Zuo, Li, Miao, Jin (CR155) 2016; 7 Bailey, Cooper, Zeitels, Smyth, Yang, Walker, Hypponen, Dunger, Ramos-Lopez, Badenhoop, Nejentsev, Todd (CR93) 2007; 56 Cooles, Pratt, Lendrem, Ng, Aspray, Isaacs (CR119) 2015; 54 Ham, Longhi, Lahiff, Cheifetz, Robson, Moss (CR105) 2014; 20 Bizzaro, Shoenfeld (CR5) 2015; 61 Bae, Lee (CR82) 2018; 64 Kouchaki, Afarini, Abolhassani, Mirhosseini, Bahmani, Masoud, Asemi (CR77) 2018; 148 Song, Bae, Lee (CR134) 2012; 31 Wang, Dabbas, Laperriere, Bitton, Soualhine, Tavera-Mendoza, Dionne, Servant, Bitton, Seidman, Mader, Behr, White (CR31) 2010; 285 England, Thiele, Anderson, Mikuls (CR112) 2018; 361 Muller, Heilmann, Poulsen, Barington, Bendtzen (CR63) 1991; 21 Lin, Liu, Davies, Chen (CR117) 2016; 11 Van Belle, Vanherwegen, Feyaerts, De Clercq, Verstuyf, Korf, Gysemans, Mathieu (CR152) 2014; 9 He, Liu, Shi, Tian, Hu, Deb, Chen, Bissonnette, Li (CR30) 2018; 159 Harroud, Richards (CR72) 2018; 24 Zehnder, Bland, Williams, McNinch, Howie, Stewart, Hewison (CR12) 2001; 86 Chen, Sims, Chen, Gu, Chen, Lipsky (CR64) 2007; 179 Bacchetta, Zaritsky, Sea, Chun, Lisse, Zavala, Nayak, Wesseling-Perry, Westerman, Hollis, Salusky, Hewison (CR32) 2014; 25 Fritsche, Mondal, Ehrnsperger, Andreesen, Kreutz (CR38) 2003; 102 Bizzarri, Pitocco, Napoli, Di Stasio, Maggi, Manfrini, Suraci, Cavallo, Cappa, Ghirlanda, Pozzilli (CR102) 2010; 33 Rosjo, Lossius, Abdelmagid, Lindstrom, Kampman, Jorgensen, Sundstrom, Olsson, Steffensen, Torkildsen, Holmoy (CR80) 2017; 23 Schlingmann, Kaufmann, Weber, Irwin, Goos, John, Misselwitz, Klaus, Kuwertz-Broking, Fehrenbach, Wingen, Guran, Hoenderop, Bindels, Prosser, Jones, Konrad (CR23) 2011; 365 Cutolo, Otsa (CR8) 2008; 17 Lagishetty, Misharin, Liu, Lisse, Chun, Ouyang, McLachlan, Adams, Hewison (CR110) 2010; 151 Bartels, Jørgensen, Agnholt, Kelsen, Hvas, Dahlerup (CR46) 2007; 7 Hewison (CR25) 2011; 86 Ananthakrishnan (CR104) 2016; 12 Jeffery, Qureshi, Gardner, Hou, Briggs, Soskic, Baker, Raza, Sansom (CR136) 2015; 10 Hewison, Freeman, Hughes, Evans, Bland, Eliopoulos, Kilby, Moss, Chakraverty (CR13) 2003; 170 Aljabri, Bokhari, Khan (CR92) 2010; 30 Jr, Holweg, Kummerfeld, Choy, Setiadi, Hackney, Haverty, Gilbert, Lin, Diehl, Fischer, Song, Musselman, Klearman, Gabay, Kavanaugh, Endres, Fox, Martin, Townsend (CR124) 2014; 16 Liu, Chen, Golan, Annunziata, Du, Dougherty, Kong, Musch, Huang, Pekow, Zheng, Bissonnette, Hanauer, Li (CR111) 2013; 123 Cooles, Isaacs, Anderson (CR149) 2013; 15 Tracy, Buckley, Raza (CR116) 2017; 39 Kreutz, Andreesen, Krause, Szabo, Ritz, Reichel (CR14) 1993; 82 Stoop, Harry, von Delwig, Isaacs, Robinson, Hilkens (CR142) 2010; 62 Gabbay, Sato, Finazzo, Duarte, Dib (CR100) 2012; 166 CR130 Dionne, Duchatelier, Seidman (CR39) 2017; 23 Yarwood, Huizinga, Worthington (CR115) 2014; 55 Ponchel, Goëb, Parmar, El-Sherbiny, Boissinot, El Jawhari, Burska, Vital, Harrison, Conaghan, Hensor, Emery (CR145) 2014; 73 Hewison (CR17) 2010; 321 Barry, Rees, Peacock, Mott, Amos, Bostick, Figueiredo, Ahnen, Bresalier, Burke, Baron (CR135) 2014; 99 Feng, Lv, Wang, Gan, Zhang, Tan (CR157) 2013; 2013 Adams, Hewison (CR24) 2008; 4 Danks, Komatsu, Guerrini, Sawa, Armaka, Kollias, Nakashima, Takayanagi (CR137) 2016; 75 Christakos, Ajibade, Dhawan, Fechner, Mady (CR1) 2011; 39 Boonstra, Barrat, Crain, Heath, Savelkoul, O’Garra (CR57) 2001; 167 Wang, Zhu, DeLuca (CR27) 2012; 523 Mawer, Hayes, Still, Davies, Lumb, Holt (CR126) 1991; 6 Li, Wei, Yin, Chen, Ma, Wu, Zhou, Zheng, Han (CR147) 2015; 8 Liu, Schenk, Walker, Dempsey, Kanchanapoomi, Wheelwright, Vazirnia, Zhang, Steinmeyer, Zugel, Hollis, Cheng, Modlin (CR34) 2009; 4 Zella, DeLuca (CR90) 2003; 88 Bhalla, Amento, Clemens, Holick, Krane (CR50) 1983; 57 Klareskog (CR139) 1991; 30 Lucas, Rodney Harris (CR70) 2018; 15 CR129 Tobon, Youinou, Saraux (CR113) 2010; 9 Furuya, Hosoi, Tanaka, Nakajima, Taniguchi, Momohara, Yamanaka (CR121) 2013; 32 Kivity, Agmon-Levin, Zisappl, Shapira, Nagy, Danko, Szekanecz, Langevitz, Shoenfeld (CR6) 2011; 8 Piemonti, Monti, Sironi, Fraticelli, Leone, Dal Cin, Allavena, Di Carlo (CR48) 2000; 164 Cantorna, Nashold, Chun, Hayes (CR56) 1996; 156 Jones, Prosser, Kaufmann (CR22) 2012; 523 Mathieu, Badenhoop (CR91) 2005; 16 Ramagopalan, Heger, Berlanga, Maugeri, Lincoln, Burrell, Handunnetthi, Handel, Disanto, Orton, Watson, Morahan, Giovannoni, Ponting, Ebers, Knight (CR97) 2010; 20 Jørgensen, Hvas, Agnholt, Christensen, Heickendorff, Dahlerup (CR106) 2013; 7 Cantorna (CR7) 2012; 523 Hewison (CR52) 2012; 71 Di Franco, Barchetta, Iannuccelli, Gerardi, Frisenda, Ceccarelli, Valesini, Cavallo (CR120) 2015; 16 Walter, Kaupper, Adler, Foersch, Bonifacio, Ziegler (CR103) 2010; 33 Froicu, Weaver, Wynn, McDowell, Welsh, Cantorna (CR108) 2003; 17 Martineau, Jolliffe, Hooper, Greenberg, Aloia, Bergman, Dubnov-Raz, Esposito, Ganmaa, Ginde, Goodall, Grant, Griffiths, Janssens, Laaksi, Manaseki-Holland, Mauger, Murdoch, Neale, Rees, Simpson, Stelmach, Kumar, Urashima, Camargo (CR159) 2017; 356 Chun, Lauridsen, Suon, Zella, Pike, Modlin, Martineau, Wilkinson, Adams, Hewison (CR21) 2010; 95 Disanto, Chaplin, Morahan, Giovannoni, Hypponen, Ebers, Ramagopalan (CR71) 2012; 10 Kim, Bang, Lee, Cho, Choi, Sung, Kim, Jun, Yoo, Kang, Kim, Suh, Shim, Lee, Lee, Chung, Choe, Shin, Lee, Han, Nath, Eyre, Bowes, Pappas, Kremer, Gonzalez-Gay, Rodriguez-Rodriguez, Arlestig, Okada, Diogo, Liao, Karlson, Raychaudhuri, Rantapaa-Dahlqvist, Martin, Klareskog, Padyukov, Gregersen, Worthington, Greenberg, Plenge, Bae (CR114) 2015; 74 von Essen, Kongsbak, Schjerling, Olgaard, Odum, Geisler (CR60) 2010; 11 Hewison (CR18) 2010; 321 Hayes, Denton, Freemont, Mawer (CR125) 1989; 48 Anaya, Restrepo-Jiménez, Ramírez-Santana (CR68) 2018; 30 Shahin, El-Farahaty, Houssen, Machaly, Sallam, ElSaid, Neseem (CR85) 2017; 26 Jeffery, R MT Cantorna (577_CR56) 1996; 156 SP Jørgensen (577_CR106) 2013; 7 LC Tetlow (577_CR158) 1999; 1 C Mathieu (577_CR98) 1994; 37 JN Stoop (577_CR142) 2010; 62 E Rosjo (577_CR81) 2015; 262 E Nikiphorou (577_CR69) 2018; 37 KS Aljabri (577_CR92) 2010; 30 FA Cooles (577_CR119) 2015; 54 ME Hayes (577_CR125) 1989; 48 LE Jeffery (577_CR136) 2015; 10 LE Jeffery (577_CR153) 2018; 88 MS Mohammad (577_CR107) 2013; 62 TL Van Belle (577_CR152) 2014; 9 X Feng (577_CR157) 2013; 2013 E Ramos-Lopez (577_CR96) 2006; 1079 W Liu (577_CR111) 2013; 123 JM Anaya (577_CR68) 2018; 30 S Yu (577_CR62) 2008; 105 G Bizzaro (577_CR5) 2015; 61 P Křenek (577_CR76) 2018; 64 JL Rodriguez-Fernandez (577_CR138) 2013; 13 AR Martineau (577_CR159) 2017; 356 M Walter (577_CR103) 2010; 33 V Meyer (577_CR37) 2017; 8 L Rolf (577_CR78) 2018; 314 ER Lopez (577_CR95) 2004; 89–90 N Li (577_CR147) 2015; 8 S Dionne (577_CR39) 2017; 23 J Lin (577_CR117) 2016; 11 LE Jeffery (577_CR9) 2016; 12 A Yarwood (577_CR115) 2014; 55 DH Gardner (577_CR154) 2015; 195 P Emery (577_CR123) 1995; 54 D Shahin (577_CR85) 2017; 26 N Liu (577_CR109) 2008; 149 PT Liu (577_CR34) 2009; 4 LE Bartels (577_CR46) 2007; 7 JD Cooper (577_CR94) 2011; 60 A Miclea (577_CR79) 2017; 7 M Bscheider (577_CR143) 2016; 148 KP Schlingmann (577_CR23) 2011; 365 R Bailey (577_CR93) 2007; 56 RF Chun (577_CR20) 2014; 144 A Ataie-Jafari (577_CR101) 2013; 32 K Muller (577_CR63) 1991; 21 BR England (577_CR112) 2018; 361 C Mathieu (577_CR91) 2005; 16 SC Bae (577_CR82) 2018; 64 B Moradi (577_CR150) 2014; 16 F Merino (577_CR61) 1989; 118 KM Sanders (577_CR160) 2010; 303 JG Zhu (577_CR10) 2013; 110 M Hewison (577_CR18) 2010; 321 LE Jeffery (577_CR59) 2009; 183 JB Zella (577_CR90) 2003; 88 EB Mawer (577_CR126) 1991; 6 M Kreutz (577_CR14) 1993; 82 SM Abdel Galil (577_CR84) 2018; 27 M Ham (577_CR105) 2014; 20 H Karimzadeh (577_CR87) 2017; 22 V Lagishetty (577_CR110) 2010; 151 T Furuya (577_CR121) 2013; 32 A Boonstra (577_CR57) 2001; 167 K Hufnaql (577_CR67) 2018; 27 M Hewison (577_CR40) 2004; 215 DN Krementsov (577_CR74) 2018; 9 MA Gabbay (577_CR100) 2012; 166 R Bouillon (577_CR28) 2008; 29 577_CR130 K Nistala (577_CR140) 2010; 107 MR von Essen (577_CR60) 2010; 11 K Kim (577_CR114) 2015; 74 O Kamisli (577_CR75) 2018; 20 AK Shirakawa (577_CR66) 2008; 180 L Piemonti (577_CR48) 2000; 164 M Di Franco (577_CR120) 2015; 16 M Hewison (577_CR17) 2010; 321 MK Higgins (577_CR118) 2013; 32 L He (577_CR30) 2018; 159 M Froicu (577_CR108) 2003; 17 GD Jr (577_CR124) 2014; 16 M Hewison (577_CR52) 2012; 71 R Lucas (577_CR70) 2018; 15 M Cutolo (577_CR8) 2008; 17 S Joshi (577_CR55) 2011; 31 AN Ananthakrishnan (577_CR104) 2016; 12 S Christakos (577_CR3) 2013; 1287 TH Kim (577_CR35) 2013; 154 MT Cantorna (577_CR7) 2012; 523 Y Wang (577_CR27) 2012; 523 A Tracy (577_CR116) 2017; 39 S Chen (577_CR64) 2007; 179 MT Cantorna (577_CR54) 2015; 7 RF Chun (577_CR21) 2010; 95 TT Wang (577_CR31) 2010; 285 577_CR129 EL Barry (577_CR135) 2014; 99 L Klareskog (577_CR139) 1991; 30 J Bacchetta (577_CR32) 2014; 25 AK Bhalla (577_CR50) 1983; 57 E Kouchaki (577_CR77) 2018; 148 C Aranow (577_CR86) 2015; 67 AW Pedersen (577_CR43) 2009; 157 HF DeLuca (577_CR2) 2014; 3 M Hewison (577_CR11) 2000; 25 D Zehnder (577_CR12) 2001; 86 M Hewison (577_CR26) 2011; 7 FAH Cooles (577_CR149) 2013; 15 C Mathieu (577_CR4) 2015; 108 S Christakos (577_CR1) 2011; 39 K Sadeghi (577_CR36) 2006; 36 GJ Tobon (577_CR113) 2010; 9 JS Adams (577_CR24) 2008; 4 LE Mokry (577_CR73) 2015; 12 M Hewison (577_CR16) 2007; 103 L Szeles (577_CR49) 2009; 182 FJ Barrat (577_CR58) 2002; 195 LE Jeffery (577_CR15) 2012; 189 G Jones (577_CR22) 2012; 523 M Varenna (577_CR131) 2012; 30 AS Franco (577_CR132) 2017; 96 A Harroud (577_CR72) 2018; 24 G Penna (577_CR41) 2000; 164 X Gu (577_CR155) 2016; 7 KH Costenbader (577_CR88) 2008; 67 G Disanto (577_CR71) 2012; 10 J Fritsche (577_CR38) 2003; 102 M Zhao (577_CR83) 2017; 6 M Hewison (577_CR25) 2011; 86 G Heine (577_CR65) 2008; 38 C Bizzarri (577_CR102) 2010; 33 Y-G Zhang (577_CR29) 2015; 5 F Baeke (577_CR151) 2011; 186 PT Liu (577_CR33) 2006; 311 T Wang (577_CR148) 2015; 74 D Li (577_CR128) 2018; 187 F Ponchel (577_CR145) 2014; 73 E Rosjo (577_CR80) 2017; 23 AG van Halteren (577_CR42) 2004; 23 AE Anderson (577_CR144) 2017; 187 S Sarkar (577_CR53) 2016; 53 JP van Hamburg (577_CR156) 2012; 71 GM Allan (577_CR133) 2016; 31 M Hewison (577_CR13) 2003; 170 GG Song (577_CR134) 2012; 31 G Penna (577_CR47) 2000; 164 X Li (577_CR99) 2009; 25 L Danks (577_CR137) 2016; 75 JP van Hamburg (577_CR141) 2011; 63 HJ Haga (577_CR122) 2013; 32 SV Ramagopalan (577_CR97) 2010; 20 JS Adams (577_CR19) 2014; 144 ME Hayes (577_CR127) 1992; 51 M Willheim (577_CR45) 1999; 84 MD Griffin (577_CR44) 2001; 98 GL Lima (577_CR89) 2016; 68 K Langdon (577_CR146) 2018; 37 DM Provvedini (577_CR51) 1986; 136 S Kivity (577_CR6) 2011; 8 |
| References_xml | – volume: 9 start-page: e109194 year: 2014 end-page: e109194 ident: CR152 article-title: 1,25-Dihydroxyvitamin D3 and Its Analog TX527 Promote a Stable Regulatory T Cell Phenotype in T Cells from Type 1 Diabetes Patients publication-title: PLoS ONE – volume: 39 start-page: 243 year: 2011 end-page: 253 ident: CR1 article-title: Vitamin D: metabolism publication-title: Endocrinol Metab – volume: 60 start-page: 1624 year: 2011 end-page: 1631 ident: CR94 article-title: Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes publication-title: Diabetes – volume: 96 start-page: e7024 year: 2017 end-page: e7024 ident: CR132 article-title: Vitamin D supplementation and disease activity in patients with immune-mediated rheumatic diseases publication-title: Medicine – volume: 1287 start-page: 45 year: 2013 end-page: 58 ident: CR3 article-title: Vitamin D: beyond bone publication-title: Ann N Y Acad Sci – volume: 62 start-page: 3656 year: 2010 end-page: 3665 ident: CR142 article-title: Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses publication-title: Arthritis Rheum – volume: 9 start-page: 1 year: 2018 end-page: 15 ident: CR74 article-title: Sex-specific gene-by-vitamin D interactions regulate susceptibility to central nervous system autoimmunity publication-title: Front Immunol – volume: 22 start-page: 4 year: 2017 ident: CR87 article-title: The effect of Vitamin D supplementation in disease activity of systemic lupus erythematosus patients with Vitamin D deficiency: a randomized clinical trial publication-title: J Res Med Sci – volume: 62 start-page: A172 year: 2013 end-page: A172 ident: CR107 article-title: PWE-103 vitamin D deficiency in crohns disease and ulcerative colitis publication-title: Gut – volume: 523 start-page: 123 year: 2012 end-page: 133 ident: CR27 article-title: Where is the vitamin D receptor? publication-title: Arch Biochem Biophys – volume: 39 start-page: 423 year: 2017 end-page: 435 ident: CR116 article-title: Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start? publication-title: Semin Immunopathol – volume: 303 start-page: 1815 year: 2010 end-page: 1822 ident: CR160 article-title: Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial publication-title: JAMA – volume: 71 start-page: 50 year: 2012 end-page: 61 ident: CR52 article-title: Vitamin D and immune function: an overview publication-title: Proc Nutr Soc – volume: 321 start-page: 103 year: 2010 end-page: 111 ident: CR17 article-title: Vitamin D and the intracrinology of innate immunity publication-title: Mol Cell Endocrinol – volume: 314 start-page: 50 year: 2018 end-page: 57 ident: CR78 article-title: Vitamin D3 supplementation and the IL-2/IL-2R pathway in multiple sclerosis: attenuation of progressive disturbances? publication-title: J Neuroimmunol – volume: 48 start-page: 723 year: 1989 end-page: 729 ident: CR125 article-title: Synthesis of the active metabolite of vitamin D, 1,25(OH)2D3, by synovial fluid macrophages in arthritic diseases publication-title: Ann Rheum Dis – volume: 154 start-page: 80 year: 2013 end-page: 85 ident: CR35 article-title: Regulation of TREM-1 expression by 1,25-dihydroxyvitamin D3 in human monocytes/macrophages publication-title: Immunol Lett – volume: 523 start-page: 103 year: 2012 end-page: 106 ident: CR7 article-title: Vitamin D, multiple sclerosis and inflammatory bowel disease publication-title: Arch Biochem Biophys – volume: 98 start-page: 6800 year: 2001 end-page: 6805 ident: CR44 article-title: Dendritic cell modulation by 1alpha,25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo publication-title: Proc Natl Acad Sci USA – volume: 10 start-page: 69 year: 2012 ident: CR71 article-title: Month of birth, vitamin D and risk of immune-mediated disease: a case control study publication-title: BMC Med – volume: 186 start-page: 132 year: 2011 end-page: 142 ident: CR151 article-title: The vitamin D analog, TX527, promotes a human CD4+ CD25 high CD127 low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation publication-title: J Immunol – volume: 4 start-page: e5810 year: 2009 ident: CR34 article-title: Convergence of IL-1beta and VDR activation pathways in human TLR2/1-induced antimicrobial responses publication-title: PLoS ONE – volume: 10 start-page: e0131539 year: 2015 ident: CR136 article-title: Vitamin D antagonises the suppressive effect of inflammatory cytokines on CTLA-4 expression and regulatory function publication-title: PLoS ONE – volume: 71 start-page: 606 year: 2012 end-page: 612 ident: CR156 article-title: TNF blockade requires 1,25(OH)2D3 to control human Th17-mediated synovial inflammation publication-title: Ann Rheum Dis – volume: 86 start-page: 888 year: 2001 end-page: 894 ident: CR12 article-title: Extrarenal expression of 25-hydroxyvitamin d(3)-1 alpha-hydroxylase publication-title: J Clin Endocrinol Metab – volume: 12 start-page: e1001866 year: 2015 ident: CR73 article-title: Vitamin D and risk of multiple sclerosis: a mendelian randomization study publication-title: PLoS Med – ident: CR129 – volume: 311 start-page: 1770 year: 2006 end-page: 1773 ident: CR33 article-title: Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response publication-title: Science – volume: 15 start-page: 352 year: 2013 ident: CR149 article-title: Treg cells in rheumatoid arthritis: an update publication-title: Curr Rheumatol Rep – volume: 102 start-page: 3314 year: 2003 end-page: 3316 ident: CR38 article-title: Regulation of 25-hydroxyvitamin D3-1 alpha-hydroxylase and production of 1 alpha,25-dihydroxyvitamin D3 by human dendritic cells publication-title: Blood – volume: 75 start-page: 1187 year: 2016 end-page: 1195 ident: CR137 article-title: RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation publication-title: Ann Rheum Dis – volume: 88 start-page: 50 year: 2018 end-page: 60 ident: CR153 article-title: Decreased sensitivity to 1,25-dihydroxyvitamin D3 in T cells from the rheumatoid joint publication-title: J Autoimmun – volume: 61 start-page: 46 year: 2015 end-page: 52 ident: CR5 article-title: Vitamin D and autoimmune thyroid diseases: facts and unresolved questions publication-title: Immunol Res – volume: 262 start-page: 2713 year: 2015 end-page: 2721 ident: CR81 article-title: Vitamin D supplementation and systemic inflammation in relapsing-remitting multiple sclerosis publication-title: J Neurol – volume: 74 start-page: e13 year: 2015 ident: CR114 article-title: High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci publication-title: Ann Rheum Dis – volume: 16 start-page: R97 year: 2014 end-page: R97 ident: CR150 article-title: CD4 CD25+/high CD127 low/− regulatory T cells are enriched in rheumatoid arthritis and osteoarthritis joints–analysis of frequency and phenotype in synovial membrane, synovial fluid and peripheral blood publication-title: Arthritis Res Ther – volume: 1 start-page: 63 year: 1999 ident: CR158 article-title: The effects of 1 alpha,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion publication-title: Arthritis Res – volume: 159 start-page: 967 year: 2018 end-page: 979 ident: CR30 article-title: Gut epithelial vitamin d receptor regulates microbiota-dependent mucosal inflammation by suppressing intestinal epithelial cell apoptosis publication-title: Endocrinology – volume: 148 start-page: 227 year: 2016 end-page: 236 ident: CR143 article-title: Vitamin D immunoregulation through dendritic cells publication-title: Immunology – volume: 36 start-page: 361 year: 2006 end-page: 370 ident: CR36 article-title: Vitamin D3 down-regulates monocyte TLR expression and triggers hyporesponsiveness to pathogen-associated molecular patterns publication-title: Eur J Immunol – volume: 361 start-page: k1036 year: 2018 end-page: k1036 ident: CR112 article-title: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications publication-title: BMJ – volume: 179 start-page: 1634 year: 2007 end-page: 1647 ident: CR64 article-title: Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation publication-title: J Immunol – volume: 67 start-page: 530 year: 2008 end-page: 535 ident: CR88 article-title: Vitamin D intake and risks of systemic lupus erythematosus and rheumatoid arthritis in women publication-title: Ann Rheum Dis – volume: 21 start-page: 121 year: 1991 end-page: 128 ident: CR63 article-title: The role of monocytes and T cells in 1,25-dihydroxyvitamin D3 mediated inhibition of B cell function in vitro publication-title: Immunopharmacology – volume: 365 start-page: 410 year: 2011 end-page: 421 ident: CR23 article-title: Mutations in CYP24A1 and idiopathic infantile hypercalcemia publication-title: N Engl J Med – volume: 164 start-page: 4443 year: 2000 end-page: 4451 ident: CR48 article-title: Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells publication-title: J Immunol (Baltimore, Md.: 1950) – volume: 164 start-page: 2405 year: 2000 end-page: 2411 ident: CR41 article-title: 1 Alpha, 25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation publication-title: J Immunol (Baltimore, Md.: 1950) – volume: 57 start-page: 1308 year: 1983 end-page: 1310 ident: CR50 article-title: Specific high-affinity receptors for 1,25-dihydroxyvitamin D3 in human peripheral blood mononuclear cells: presence in monocytes and induction in T lymphocytes following activation publication-title: J Clin Endocrinol Metab – volume: 64 start-page: 7 year: 2018 end-page: 13 ident: CR82 article-title: Association between Vitamin D level and/or deficiency, and systemic lupus erythematosus: a meta-analysis publication-title: Cell Mol Biol – volume: 11 start-page: e0146351 year: 2016 ident: CR117 article-title: Serum vitamin D level and rheumatoid arthritis disease activity: review and meta-analysis publication-title: PLoS ONE – volume: 523 start-page: 9 year: 2012 end-page: 18 ident: CR22 article-title: 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D publication-title: Arch Biochem Biophys – volume: 86 start-page: 23 year: 2011 end-page: 62 ident: CR25 article-title: Vitamin D and innate and adaptive immunity publication-title: Vitam Horm – volume: 183 start-page: 5458 year: 2009 end-page: 5467 ident: CR59 article-title: 1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3 publication-title: J Immunol – volume: 74 start-page: 1293 year: 2015 end-page: 1301 ident: CR148 article-title: Regulatory T cells in rheumatoid arthritis showed increased plasticity toward Th17 but retained suppressive function in peripheral blood publication-title: Ann Rheum Dis – volume: 103 start-page: 316 year: 2007 end-page: 321 ident: CR16 article-title: Extra-renal 25-hydroxyvitamin D3-1alpha-hydroxylase in human health and disease publication-title: J Steroid Biochem Mol Biol – volume: 7 start-page: e00761 year: 2017 ident: CR79 article-title: Vitamin D supplementation differentially affects seasonal multiple sclerosis disease activity publication-title: Brain Behav – volume: 16 start-page: 1 year: 2014 end-page: 18 ident: CR124 article-title: Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics publication-title: Arthritis Res Ther – volume: 7 start-page: 1755 year: 2007 end-page: 1764 ident: CR46 article-title: 1,25-dihydroxyvitamin D3 and dexamethasone increase interleukin-10 production in CD4+ T cells from patients with Crohn’s disease publication-title: Int Immunopharmacol – volume: 30 start-page: 454 year: 2010 end-page: 458 ident: CR92 article-title: Glycemic changes after vitamin D supplementation in patients with type 1 diabetes mellitus and vitamin D deficiency publication-title: Ann Saudi Med – volume: 7 start-page: e407 year: 2013 end-page: e413 ident: CR106 article-title: Active Crohn’s disease is associated with low vitamin D levels publication-title: J Crohn’s Colitis – volume: 170 start-page: 5382 year: 2003 end-page: 5390 ident: CR13 article-title: Differential regulation of vitamin D receptor and its ligand in human monocyte-derived dendritic cells publication-title: J Immunol – volume: 144 start-page: 132 issue: Pt A year: 2014 end-page: 137 ident: CR20 article-title: Vitamin D and DBP: the free hormone hypothesis revisited publication-title: J Steroid Biochem Mol Biol – volume: 118 start-page: 328 year: 1989 end-page: 336 ident: CR61 article-title: Regulation of natural killer cytotoxicity by 1,25-dihydroxyvitamin D3 publication-title: Cell Immunol – volume: 6 start-page: 733 year: 1991 end-page: 739 ident: CR126 article-title: Evidence for nonrenal synthesis of 1,25-dihydroxyvitamin D in patients with inflammatory arthritis publication-title: J Bone Miner Res – volume: 89–90 start-page: 155 year: 2004 end-page: 157 ident: CR95 article-title: CYP27B1 polymorphisms variants are associated with type 1 diabetes mellitus in Germans publication-title: J Steroid Biochem Mol Biol – volume: 107 start-page: 14751 year: 2010 end-page: 14756 ident: CR140 article-title: Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment publication-title: Proc Natl Acad Sci USA – volume: 20 start-page: 78 year: 2018 end-page: 81 ident: CR75 article-title: The association between vitamin D receptor polymorphisms and multiple sclerosis in a Turkish population publication-title: Mult Scler Relat Disord – volume: 108 start-page: 201 year: 2015 end-page: 209 ident: CR4 article-title: Vitamin D and diabetes: where do we stand? publication-title: Diabetes Res Clin Pract – volume: 17 start-page: 2386 year: 2003 end-page: 2392 ident: CR108 article-title: A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases publication-title: Mol Endocrinol – volume: 195 start-page: 2657 year: 2015 end-page: 2665 ident: CR154 article-title: 1,25(OH)2D3 promotes the efficacy of CD28 costimulation blockade by abatacept publication-title: J Immunol – volume: 33 start-page: 1443 year: 2010 end-page: 1448 ident: CR103 article-title: No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes publication-title: Diabetes Care – volume: 215 start-page: 31 year: 2004 end-page: 38 ident: CR40 article-title: Vitamin D and barrier function: a novel role for extra-renal 1 alpha-hydroxylase publication-title: Mol Cell Endocrinol – volume: 29 start-page: 726 year: 2008 end-page: 776 ident: CR28 article-title: Vitamin D and human health: lessons from vitamin D receptor null mice publication-title: Endocr Rev – volume: 23 start-page: 395 year: 2017 end-page: 402 ident: CR80 article-title: Effect of high-dose vitamin D3 supplementation on antibody responses against Epstein-Barr virus in relapsing-remitting multiple sclerosis publication-title: Mult Scler – volume: 23 start-page: 233 year: 2004 end-page: 239 ident: CR42 article-title: 1alpha,25-dihydroxyvitamin D3 or analogue treated dendritic cells modulate human autoreactive T cells via the selective induction of apoptosis publication-title: J Autoimmun – volume: 6 start-page: 43 year: 2017 end-page: 51 ident: CR83 article-title: Severe vitamin D deficiency affects the expression of autophagy related genes in PBMCs and T-cell subsets in active systemic lupus erythematosus publication-title: Am J Clin Exp Immunol – volume: 38 start-page: 2210 year: 2008 end-page: 2218 ident: CR65 article-title: 1,25-dihydroxyvitamin D(3) promotes IL-10 production in human B cells publication-title: Eur J Immunol – volume: 167 start-page: 4974 year: 2001 end-page: 4980 ident: CR57 article-title: 1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells publication-title: J Immunol – volume: 16 start-page: 53 year: 2015 ident: CR120 article-title: Hypovitaminosis D in recent onset rheumatoid arthritis is predictive of reduced response to treatment and increased disease activity: a 12 month follow-up study publication-title: BMC Musculoskelet Disord – volume: 164 start-page: 2405 year: 2000 end-page: 2411 ident: CR47 article-title: 1,25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation publication-title: J Immunol – volume: 8 start-page: 15043 year: 2015 end-page: 15053 ident: CR147 article-title: The abnormal expression of CCR47 and CCR47 on Tregs in rheumatoid arthritis publication-title: Int J Clin Exp Med – volume: 64 start-page: 559 year: 2018 end-page: 566 ident: CR76 article-title: The impact of five VDR polymorphisms on multiple sclerosis risk and progression: a case–control and genotype-phenotype study publication-title: J Mol Neurosci – volume: 166 start-page: 601 year: 2012 end-page: 607 ident: CR100 article-title: Effect of cholecalciferol as adjunctive therapy with insulin on protective immunologic profile and decline of residual beta-cell function in new-onset type 1 diabetes mellitus publication-title: Arch Pediatr Adolesc Med – volume: 56 start-page: 2616 year: 2007 end-page: 2621 ident: CR93 article-title: Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes publication-title: Diabetes – volume: 7 start-page: e2423 year: 2016 ident: CR155 article-title: 1, 25-dihydroxy-vitamin D3 with tumor necrosis factor-alpha protects against rheumatoid arthritis by promoting p53 acetylation-mediated apoptosis via Sirt1 in synoviocytes publication-title: Cell Death Dis – volume: 182 start-page: 2074 year: 2009 end-page: 2083 ident: CR49 article-title: 1,25-dihydroxyvitamin D3 is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype publication-title: J Immunol (Baltimore, Md.: 1950) – volume: 8 start-page: 1 year: 2017 end-page: 15 ident: CR37 article-title: Methylation of the Vitamin D Receptor (VDR) gene, together with genetic variation, race, and environment influence the signaling efficacy of the toll-like receptor 2/1-VDR pathway publication-title: Front Immunol – volume: 157 start-page: 48 year: 2009 end-page: 59 ident: CR43 article-title: Phenotypic and functional markers for 1α,25-dihydroxyvitamin D3-modified regulatory dendritic cells publication-title: Clin Exp Immunol – volume: 54 start-page: 944 year: 1995 end-page: 947 ident: CR123 article-title: Early rheumatoid arthritis: time to aim for remission? publication-title: Ann Rheum Dis – volume: 26 start-page: 917 year: 2017 end-page: 926 ident: CR85 article-title: Serum 25-OH vitamin D level in treatment-naive systemic lupus erythematosus patients: relation to disease activity, IL-23 and IL-17 publication-title: Lupus – volume: 51 start-page: 220 year: 1992 end-page: 226 ident: CR127 article-title: Differential metabolism of 25-hydroxyvitamin D3 by cultured synovial fluid macrophages and fibroblast-like cells from patients with arthritis publication-title: Ann Rheum Dis – volume: 95 start-page: 3368 year: 2010 end-page: 3376 ident: CR21 article-title: Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D publication-title: J Clin Endocrinol Metab – volume: 144 start-page: 22 year: 2014 end-page: 27 ident: CR19 article-title: Regulation of the extrarenal CYP27B1-hydroxylase publication-title: J Steroid Biochem Mol Biol – volume: 11 start-page: 344 year: 2010 end-page: 349 ident: CR60 article-title: Vitamin D controls T cell antigen receptor signaling and activation of human T cells publication-title: Nat Immunol – volume: 2013 start-page: 160123 year: 2013 ident: CR157 article-title: Modulatory effect of 1,25-dihydroxyvitamin D 3 on IL1 β-induced RANKL, OPG, TNF α, and IL-6 expression in human rheumatoid synoviocyte MH7A publication-title: Clin Dev Immunol – volume: 82 start-page: 1300 year: 1993 end-page: 1307 ident: CR14 article-title: 1,25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages publication-title: Blood – volume: 27 start-page: 72 year: 2018 end-page: 78 ident: CR67 article-title: Vitamin A and D in allergy: from experimental animal models and cellular studies to human disease publication-title: Allergo J Int – volume: 37 start-page: 552 year: 1994 end-page: 558 ident: CR98 article-title: Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3 publication-title: Diabetologia – volume: 31 start-page: 1733 year: 2012 end-page: 1739 ident: CR134 article-title: Association between vitamin D intake and the risk of rheumatoid arthritis: a meta-analysis publication-title: Clin Rheumatol – volume: 31 start-page: 780 year: 2016 end-page: 791 ident: CR133 article-title: Vitamin D: a narrative review examining the evidence for ten beliefs publication-title: J Gen Intern Med – volume: 30 start-page: 53 issue: Suppl 1 year: 1991 end-page: 57 ident: CR139 article-title: Antigen presentation in joints in the pathogenesis of arthritis publication-title: Br J Rheumatol – volume: 23 start-page: 557 year: 2017 end-page: 565 ident: CR39 article-title: The influence of vitamin D on M1 and M2 macrophages in patients with Crohn’s disease publication-title: Innate Immun – volume: 68 start-page: 91 year: 2016 end-page: 98 ident: CR89 article-title: Vitamin D supplementation in adolescents and young adults with juvenile systemic lupus erythematosus for improvement in disease activity and fatigue scores: a randomized, double-blind, placebo-controlled trial publication-title: Arthritis Care Res (Hoboken) – volume: 16 start-page: 261 year: 2005 end-page: 266 ident: CR91 article-title: Vitamin D and type 1 diabetes mellitus: state of the art publication-title: Trends Endocrinol Metab – volume: 30 start-page: 714 year: 2012 end-page: 719 ident: CR131 article-title: Determinants and effects of vitamin D supplementation on serum 25-hydroxy-vitamin D levels in patients with rheumatoid arthritis publication-title: Clin Exp Rheumatol – volume: 15 start-page: 1726 year: 2018 ident: CR70 article-title: On the nature of evidence and ‘proving’ causality: smoking and lung cancer vs. sun exposure, vitamin D and multiple sclerosis publication-title: Int J Environ Res Public Health – volume: 110 start-page: 15650 year: 2013 end-page: 15655 ident: CR10 article-title: CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo publication-title: Proc Natl Acad Sci USA – volume: 33 start-page: 1962 year: 2010 end-page: 1963 ident: CR102 article-title: No protective effect of calcitriol on beta-cell function in recent-onset type 1 diabetes: the IMDIAB XIII trial publication-title: Diabetes Care – volume: 20 start-page: 1352 year: 2010 end-page: 1360 ident: CR97 article-title: A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution publication-title: Genome Res – volume: 12 start-page: 513 year: 2016 end-page: 515 ident: CR104 article-title: Vitamin D and inflammatory bowel disease publication-title: Gastroenterol Hepatol – volume: 151 start-page: 2423 year: 2010 end-page: 2432 ident: CR110 article-title: Vitamin D deficiency in mice impairs colonic antibacterial activity and predisposes to colitis publication-title: Endocrinology – volume: 7 start-page: 337 year: 2011 end-page: 345 ident: CR26 article-title: Antibacterial effects of vitamin D publication-title: Nat Rev – volume: 54 start-page: 374 year: 2015 end-page: 375 ident: CR119 article-title: Retrospective analysis of the role of serum vitamin D in early rheumatic disease publication-title: Rheumatology – volume: 4 start-page: 80 year: 2008 end-page: 90 ident: CR24 article-title: Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity publication-title: Nat Clin Pract Endocrinol Metab – volume: 156 start-page: 2674 year: 1996 end-page: 2679 ident: CR56 article-title: Vitamin A down-regulation of IFN-gamma synthesis in cloned mouse Th1 lymphocytes depends on the CD28 costimulatory pathway publication-title: J Immunol – volume: 5 start-page: 10642 year: 2015 ident: CR29 article-title: Tight junction CLDN2 gene is a direct target of the vitamin D receptor publication-title: Sci Rep – volume: 63 start-page: 73 year: 2011 end-page: 83 ident: CR141 article-title: Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production publication-title: Arthritis Rheum – volume: 88 start-page: 216 year: 2003 end-page: 222 ident: CR90 article-title: Vitamin D and autoimmune diabetes publication-title: J Cell Biochem – volume: 30 start-page: 350 year: 2018 end-page: 360 ident: CR68 article-title: The autoimmune ecology: an update publication-title: Curr Opin Rheumatol – volume: 195 start-page: 603 year: 2002 end-page: 616 ident: CR58 article-title: In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines publication-title: J Exp Med – volume: 37 start-page: 206 year: 2018 end-page: 214 ident: CR146 article-title: Regulatory T-cell dynamics with abatacept treatment in rheumatoid arthritis publication-title: Int Rev Immunol – volume: 187 start-page: 1 year: 2018 end-page: 8 ident: CR128 article-title: Serum and synovial fluid vitamin D metabolites and rheumatoid arthritis publication-title: J Steroid Biochem Mol Biol – volume: 12 start-page: 201 year: 2016 end-page: 210 ident: CR9 article-title: Vitamin D in rheumatoid arthritis-towards clinical application publication-title: Nat Rev Rheumatol – volume: 73 start-page: 2047 year: 2014 end-page: 2053 ident: CR145 article-title: An immunological biomarker to predict MTX response in early RA publication-title: Ann Rheum Dis – volume: 285 start-page: 2227 year: 2010 end-page: 2231 ident: CR31 article-title: Direct and indirect induction by 1,25-dihydroxyvitamin D3 of the NOD2/CARD15-defensin beta2 innate immune pathway defective in Crohn disease publication-title: J Biol Chem – volume: 136 start-page: 2734 year: 1986 end-page: 2740 ident: CR51 article-title: 1 alpha,25-Dihydroxyvitamin D3-binding macromolecules in human B lymphocytes: effects on immunoglobulin production publication-title: J Immunol – volume: 321 start-page: 103 year: 2010 end-page: 111 ident: CR18 article-title: Vitamin D and the intracrinology of innate immunity publication-title: Mol Cell Endocrinol – volume: 27 start-page: 199 year: 2018 end-page: 209 ident: CR84 article-title: Interferon alpha gene expression and serum level association with low vitamin D levels in Egyptian female patients with systemic lupus erythematosus publication-title: Lupus – volume: 187 start-page: 113 year: 2017 end-page: 123 ident: CR144 article-title: Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4(+) T cells partly via transforming growth factor-beta1 publication-title: Clin Exp Immunol – volume: 17 start-page: 6 year: 2008 end-page: 10 ident: CR8 article-title: Review: vitamin D, immunity and lupus publication-title: Lupus – volume: 25 start-page: 141 year: 2000 end-page: 148 ident: CR11 article-title: 1alpha-Hydroxylase and the action of vitamin D publication-title: J Mol Endocrinol – volume: 84 start-page: 3739 year: 1999 end-page: 3744 ident: CR45 article-title: Regulatory effects of 1alpha,25-dihydroxyvitamin D3 on the cytokine production of human peripheral blood lymphocytes publication-title: J Clin Endocrinol Metab – volume: 13 start-page: 712 year: 2013 end-page: 719 ident: CR138 article-title: Antigen presentation by dendritic cells in rheumatoid arthritis publication-title: Curr Top Med Chem – volume: 31 start-page: 3653 year: 2011 end-page: 3669 ident: CR55 article-title: 1,25-dihydroxyvitamin D(3) ameliorates Th17 autoimmunity via transcriptional modulation of interleukin-17A publication-title: Mol Cell Biol – volume: 25 start-page: 564 year: 2014 end-page: 572 ident: CR32 article-title: Suppression of iron-regulatory hepcidin by vitamin D publication-title: J Am Soc Nephrol – volume: 67 start-page: 1848 year: 2015 end-page: 1857 ident: CR86 article-title: Randomized, double-blind, placebo-controlled trial of the effect of vitamin D3 on the interferon signature in patients with systemic lupus erythematosus publication-title: Arthritis Rheumatol – volume: 3 start-page: 1 year: 2014 end-page: 8 ident: CR2 article-title: History of the discovery of vitamin D and its active metabolites publication-title: BoneKEy Rep – volume: 53 start-page: 132 year: 2016 end-page: 145 ident: CR53 article-title: Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer publication-title: Crit Rev Clin Lab Sci – volume: 180 start-page: 2786 year: 2008 end-page: 2795 ident: CR66 article-title: 1,25-Dihydroxyvitamin D3 induces CCR16 expression in terminally differentiating human B cells publication-title: J Immunol – volume: 37 start-page: 803 year: 2018 end-page: 810 ident: CR69 article-title: A cross-sectional study of vitamin D levels in a large cohort of patients with rheumatic diseases publication-title: Clin Rheumatol – volume: 8 start-page: 243 year: 2011 end-page: 247 ident: CR6 article-title: Vitamin D and autoimmune thyroid diseases publication-title: Cell Mol Immunol – volume: 189 start-page: 5155 year: 2012 end-page: 5164 ident: CR15 article-title: Availability of 25-hydroxyvitamin D3 to APCs controls the balance between regulatory and inflammatory T cell responses publication-title: J Immunol – volume: 7 start-page: 3011 year: 2015 end-page: 3021 ident: CR54 article-title: Vitamin D and 1,25(OH)2D regulation of T cells publication-title: Nutrients – volume: 9 start-page: A288 year: 2010 end-page: 292 ident: CR113 article-title: The environment, geo-epidemiology, and autoimmune disease: rheumatoid arthritis publication-title: Autoimmun Rev – volume: 105 start-page: 5207 year: 2008 end-page: 5212 ident: CR62 article-title: The vitamin D receptor is required for iNKT cell development publication-title: Proc Natl Acad Sci USA – volume: 24 start-page: 80 year: 2018 end-page: 85 ident: CR72 article-title: Mendelian randomization in multiple sclerosis: a causal role for vitamin D and obesity? publication-title: Mult Scler – volume: 20 start-page: 856 year: 2014 end-page: 860 ident: CR105 article-title: Vitamin D levels in adults with Crohn’s disease are responsive to disease activity and treatment publication-title: Inflamm Bowel Dis – ident: CR130 – volume: 99 start-page: E2133 year: 2014 end-page: 2137 ident: CR135 article-title: Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial publication-title: J Clin Endocrinol Metab – volume: 55 start-page: 199 year: 2014 end-page: 209 ident: CR115 article-title: The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA publication-title: Rheumatology – volume: 32 start-page: 629 year: 2013 end-page: 633 ident: CR122 article-title: Severe deficiency of 25-hydroxyvitamin D(3) (25-OH-D(3)) is associated with high disease activity of rheumatoid arthritis publication-title: Clin Rheumatol – volume: 356 start-page: i6583 year: 2017 ident: CR159 article-title: Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data publication-title: BMJ – volume: 148 start-page: 1380 year: 2018 end-page: 1386 ident: CR77 article-title: High-dose ω-3 fatty acid plus vitamin D3 supplementation affects clinical symptoms and metabolic status of patients with multiple sclerosis: a randomized controlled clinical trial publication-title: J Nutr – volume: 32 start-page: 911 year: 2013 end-page: 917 ident: CR101 article-title: A randomized placebo-controlled trial of alphacalcidol on the preservation of beta cell function in children with recent onset type 1 diabetes publication-title: Clini Nutr (Edinburgh, Scotland) – volume: 32 start-page: 863 year: 2013 end-page: 867 ident: CR118 article-title: The effect of vitamin D levels on the assessment of disease activity in rheumatoid arthritis publication-title: Clin Rheumatol – volume: 123 start-page: 3983 year: 2013 end-page: 3996 ident: CR111 article-title: Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis publication-title: J Clin Investig – volume: 149 start-page: 4799 year: 2008 end-page: 4808 ident: CR109 article-title: Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation publication-title: Endocrinology – volume: 25 start-page: 411 year: 2009 end-page: 416 ident: CR99 article-title: Protective effects of 1-alpha-hydroxyvitamin D3 on residual beta-cell function in patients with adult-onset latent autoimmune diabetes (LADA) publication-title: Diabetes/Metab Res Rev – volume: 1079 start-page: 327 year: 2006 end-page: 334 ident: CR96 article-title: Protection from type 1 diabetes by vitamin D receptor haplotypes publication-title: Ann N Y Acad Sci – volume: 32 start-page: 1081 year: 2013 end-page: 1087 ident: CR121 article-title: Prevalence of and factors associated with vitamin D deficiency in 4793 Japanese patients with rheumatoid arthritis publication-title: Clin Rheumatol – volume: 144 start-page: 132 issue: Pt A year: 2014 ident: 577_CR20 publication-title: J Steroid Biochem Mol Biol doi: 10.1016/j.jsbmb.2013.09.012 – volume: 25 start-page: 141 year: 2000 ident: 577_CR11 publication-title: J Mol Endocrinol doi: 10.1677/jme.0.0250141 – volume: 103 start-page: 316 year: 2007 ident: 577_CR16 publication-title: J Steroid Biochem Mol Biol doi: 10.1016/j.jsbmb.2006.12.078 – volume: 57 start-page: 1308 year: 1983 ident: 577_CR50 publication-title: J Clin Endocrinol Metab doi: 10.1210/jcem-57-6-1308 – ident: 577_CR130 – volume: 30 start-page: 714 year: 2012 ident: 577_CR131 publication-title: Clin Exp Rheumatol – volume: 20 start-page: 856 year: 2014 ident: 577_CR105 publication-title: Inflamm Bowel Dis doi: 10.1097/MIB.0000000000000016 – volume: 9 start-page: 1 year: 2018 ident: 577_CR74 publication-title: Front Immunol doi: 10.3389/fimmu.2018.01622 – volume: 64 start-page: 559 year: 2018 ident: 577_CR76 publication-title: J Mol Neurosci doi: 10.1007/s12031-018-1034-1 – volume: 55 start-page: 199 year: 2014 ident: 577_CR115 publication-title: Rheumatology doi: 10.1093/rheumatology/keu323 – volume: 61 start-page: 46 year: 2015 ident: 577_CR5 publication-title: Immunol Res doi: 10.1007/s12026-014-8579-z – volume: 523 start-page: 123 year: 2012 ident: 577_CR27 publication-title: Arch Biochem Biophys doi: 10.1016/j.abb.2012.04.001 – volume: 36 start-page: 361 year: 2006 ident: 577_CR36 publication-title: Eur J Immunol doi: 10.1002/eji.200425995 – volume: 12 start-page: e1001866 year: 2015 ident: 577_CR73 publication-title: PLoS Med doi: 10.1371/journal.pmed.1001866 – volume: 154 start-page: 80 year: 2013 ident: 577_CR35 publication-title: Immunol Lett doi: 10.1016/j.imlet.2013.08.012 – volume: 183 start-page: 5458 year: 2009 ident: 577_CR59 publication-title: J Immunol doi: 10.4049/jimmunol.0803217 – volume: 95 start-page: 3368 year: 2010 ident: 577_CR21 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2010-0195 – volume: 321 start-page: 103 year: 2010 ident: 577_CR17 publication-title: Mol Cell Endocrinol doi: 10.1016/j.mce.2010.02.013 – volume: 30 start-page: 454 year: 2010 ident: 577_CR92 publication-title: Ann Saudi Med doi: 10.4103/0256-4947.72265 – volume: 215 start-page: 31 year: 2004 ident: 577_CR40 publication-title: Mol Cell Endocrinol doi: 10.1016/j.mce.2003.11.017 – volume: 186 start-page: 132 year: 2011 ident: 577_CR151 publication-title: J Immunol doi: 10.4049/jimmunol.1000695 – volume: 53 start-page: 132 year: 2016 ident: 577_CR53 publication-title: Crit Rev Clin Lab Sci doi: 10.3109/10408363.2015.1094443 – volume: 17 start-page: 2386 year: 2003 ident: 577_CR108 publication-title: Mol Endocrinol doi: 10.1210/me.2003-0281 – volume: 110 start-page: 15650 year: 2013 ident: 577_CR10 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1315006110 – volume: 31 start-page: 1733 year: 2012 ident: 577_CR134 publication-title: Clin Rheumatol doi: 10.1007/s10067-012-2080-7 – volume: 148 start-page: 227 year: 2016 ident: 577_CR143 publication-title: Immunology doi: 10.1111/imm.12610 – volume: 187 start-page: 113 year: 2017 ident: 577_CR144 publication-title: Clin Exp Immunol doi: 10.1111/cei.12870 – volume: 6 start-page: 733 year: 1991 ident: 577_CR126 publication-title: J Bone Miner Res doi: 10.1002/jbmr.5650060711 – volume: 195 start-page: 2657 year: 2015 ident: 577_CR154 publication-title: J Immunol doi: 10.4049/jimmunol.1500306 – volume: 30 start-page: 53 issue: Suppl 1 year: 1991 ident: 577_CR139 publication-title: Br J Rheumatol – volume: 32 start-page: 629 year: 2013 ident: 577_CR122 publication-title: Clin Rheumatol doi: 10.1007/s10067-012-2154-6 – volume: 144 start-page: 22 year: 2014 ident: 577_CR19 publication-title: J Steroid Biochem Mol Biol doi: 10.1016/j.jsbmb.2013.12.009 – volume: 31 start-page: 780 year: 2016 ident: 577_CR133 publication-title: J Gen Intern Med doi: 10.1007/s11606-016-3645-y – volume: 23 start-page: 395 year: 2017 ident: 577_CR80 publication-title: Mult Scler doi: 10.1177/1352458516654310 – volume: 123 start-page: 3983 year: 2013 ident: 577_CR111 publication-title: J Clin Investig doi: 10.1172/JCI65842 – volume: 361 start-page: k1036 year: 2018 ident: 577_CR112 publication-title: BMJ doi: 10.1136/bmj.k1036 – volume: 356 start-page: i6583 year: 2017 ident: 577_CR159 publication-title: BMJ doi: 10.1136/bmj.i6583 – volume: 179 start-page: 1634 year: 2007 ident: 577_CR64 publication-title: J Immunol doi: 10.4049/jimmunol.179.3.1634 – volume: 11 start-page: e0146351 year: 2016 ident: 577_CR117 publication-title: PLoS ONE doi: 10.1371/journal.pone.0146351 – volume: 262 start-page: 2713 year: 2015 ident: 577_CR81 publication-title: J Neurol doi: 10.1007/s00415-015-7902-5 – volume: 136 start-page: 2734 year: 1986 ident: 577_CR51 publication-title: J Immunol doi: 10.4049/jimmunol.136.8.2734 – volume: 20 start-page: 1352 year: 2010 ident: 577_CR97 publication-title: Genome Res doi: 10.1101/gr.107920.110 – ident: 577_CR129 – volume: 32 start-page: 911 year: 2013 ident: 577_CR101 publication-title: Clini Nutr (Edinburgh, Scotland) doi: 10.1016/j.clnu.2013.01.012 – volume: 108 start-page: 201 year: 2015 ident: 577_CR4 publication-title: Diabetes Res Clin Pract doi: 10.1016/j.diabres.2015.01.036 – volume: 27 start-page: 72 year: 2018 ident: 577_CR67 publication-title: Allergo J Int doi: 10.1007/s40629-018-0054-2 – volume: 89–90 start-page: 155 year: 2004 ident: 577_CR95 publication-title: J Steroid Biochem Mol Biol doi: 10.1016/j.jsbmb.2004.03.095 – volume: 6 start-page: 43 year: 2017 ident: 577_CR83 publication-title: Am J Clin Exp Immunol – volume: 7 start-page: 1755 year: 2007 ident: 577_CR46 publication-title: Int Immunopharmacol doi: 10.1016/j.intimp.2007.09.016 – volume: 88 start-page: 216 year: 2003 ident: 577_CR90 publication-title: J Cell Biochem doi: 10.1002/jcb.10347 – volume: 118 start-page: 328 year: 1989 ident: 577_CR61 publication-title: Cell Immunol doi: 10.1016/0008-8749(89)90381-X – volume: 33 start-page: 1443 year: 2010 ident: 577_CR103 publication-title: Diabetes Care doi: 10.2337/dc09-2297 – volume: 63 start-page: 73 year: 2011 ident: 577_CR141 publication-title: Arthritis Rheum doi: 10.1002/art.30093 – volume: 99 start-page: E2133 year: 2014 ident: 577_CR135 publication-title: J Clin Endocrinol Metab doi: 10.1210/jc.2014-1389 – volume: 30 start-page: 350 year: 2018 ident: 577_CR68 publication-title: Curr Opin Rheumatol doi: 10.1097/BOR.0000000000000498 – volume: 37 start-page: 803 year: 2018 ident: 577_CR69 publication-title: Clin Rheumatol doi: 10.1007/s10067-017-3870-8 – volume: 9 start-page: A288 year: 2010 ident: 577_CR113 publication-title: Autoimmun Rev doi: 10.1016/j.autrev.2009.11.019 – volume: 37 start-page: 206 year: 2018 ident: 577_CR146 publication-title: Int Rev Immunol doi: 10.1080/08830185.2018.1465943 – volume: 15 start-page: 1726 year: 2018 ident: 577_CR70 publication-title: Int J Environ Res Public Health doi: 10.3390/ijerph15081726 – volume: 26 start-page: 917 year: 2017 ident: 577_CR85 publication-title: Lupus doi: 10.1177/0961203316682095 – volume: 167 start-page: 4974 year: 2001 ident: 577_CR57 publication-title: J Immunol doi: 10.4049/jimmunol.167.9.4974 – volume: 75 start-page: 1187 year: 2016 ident: 577_CR137 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2014-207137 – volume: 21 start-page: 121 year: 1991 ident: 577_CR63 publication-title: Immunopharmacology doi: 10.1016/0162-3109(91)90015-Q – volume: 7 start-page: e00761 year: 2017 ident: 577_CR79 publication-title: Brain Behav doi: 10.1002/brb3.761 – volume: 523 start-page: 9 year: 2012 ident: 577_CR22 publication-title: Arch Biochem Biophys doi: 10.1016/j.abb.2011.11.003 – volume: 164 start-page: 4443 year: 2000 ident: 577_CR48 publication-title: J Immunol (Baltimore, Md.: 1950) doi: 10.4049/jimmunol.164.9.4443 – volume: 98 start-page: 6800 year: 2001 ident: 577_CR44 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.121172198 – volume: 33 start-page: 1962 year: 2010 ident: 577_CR102 publication-title: Diabetes Care doi: 10.2337/dc10-0814 – volume: 16 start-page: 1 year: 2014 ident: 577_CR124 publication-title: Arthritis Res Ther – volume: 86 start-page: 888 year: 2001 ident: 577_CR12 publication-title: J Clin Endocrinol Metab – volume: 7 start-page: 3011 year: 2015 ident: 577_CR54 publication-title: Nutrients doi: 10.3390/nu7043011 – volume: 20 start-page: 78 year: 2018 ident: 577_CR75 publication-title: Mult Scler Relat Disord doi: 10.1016/j.msard.2018.01.002 – volume: 67 start-page: 1848 year: 2015 ident: 577_CR86 publication-title: Arthritis Rheumatol doi: 10.1002/art.39108 – volume: 314 start-page: 50 year: 2018 ident: 577_CR78 publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2017.11.007 – volume: 54 start-page: 374 year: 2015 ident: 577_CR119 publication-title: Rheumatology doi: 10.1093/rheumatology/keu420 – volume: 22 start-page: 4 year: 2017 ident: 577_CR87 publication-title: J Res Med Sci doi: 10.4103/1735-1995.199089 – volume: 102 start-page: 3314 year: 2003 ident: 577_CR38 publication-title: Blood doi: 10.1182/blood-2002-11-3521 – volume: 164 start-page: 2405 year: 2000 ident: 577_CR41 publication-title: J Immunol (Baltimore, Md.: 1950) doi: 10.4049/jimmunol.164.5.2405 – volume: 74 start-page: e13 year: 2015 ident: 577_CR114 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-204749 – volume: 1287 start-page: 45 year: 2013 ident: 577_CR3 publication-title: Ann N Y Acad Sci doi: 10.1111/nyas.12129 – volume: 4 start-page: 80 year: 2008 ident: 577_CR24 publication-title: Nat Clin Pract Endocrinol Metab doi: 10.1038/ncpendmet0716 – volume: 3 start-page: 1 year: 2014 ident: 577_CR2 publication-title: BoneKEy Rep – volume: 148 start-page: 1380 year: 2018 ident: 577_CR77 publication-title: J Nutr doi: 10.1093/jn/nxy116 – volume: 7 start-page: e2423 year: 2016 ident: 577_CR155 publication-title: Cell Death Dis doi: 10.1038/cddis.2016.300 – volume: 1079 start-page: 327 year: 2006 ident: 577_CR96 publication-title: Ann N Y Acad Sci doi: 10.1196/annals.1375.050 – volume: 25 start-page: 411 year: 2009 ident: 577_CR99 publication-title: Diabetes/Metab Res Rev doi: 10.1002/dmrr.977 – volume: 51 start-page: 220 year: 1992 ident: 577_CR127 publication-title: Ann Rheum Dis doi: 10.1136/ard.51.2.220 – volume: 23 start-page: 557 year: 2017 ident: 577_CR39 publication-title: Innate Immun doi: 10.1177/1753425917721965 – volume: 8 start-page: 243 year: 2011 ident: 577_CR6 publication-title: Cell Mol Immunol doi: 10.1038/cmi.2010.73 – volume: 37 start-page: 552 year: 1994 ident: 577_CR98 publication-title: Diabetologia doi: 10.1007/BF00403372 – volume: 8 start-page: 15043 year: 2015 ident: 577_CR147 publication-title: Int J Clin Exp Med – volume: 1 start-page: 63 year: 1999 ident: 577_CR158 publication-title: Arthritis Res doi: 10.1186/ar12 – volume: 48 start-page: 723 year: 1989 ident: 577_CR125 publication-title: Ann Rheum Dis doi: 10.1136/ard.48.9.723 – volume: 39 start-page: 243 year: 2011 ident: 577_CR1 publication-title: Endocrinol Metab – volume: 5 start-page: 10642 year: 2015 ident: 577_CR29 publication-title: Sci Rep doi: 10.1038/srep10642 – volume: 24 start-page: 80 year: 2018 ident: 577_CR72 publication-title: Mult Scler doi: 10.1177/1352458517737373 – volume: 10 start-page: 69 year: 2012 ident: 577_CR71 publication-title: BMC Med doi: 10.1186/1741-7015-10-69 – volume: 166 start-page: 601 year: 2012 ident: 577_CR100 publication-title: Arch Pediatr Adolesc Med doi: 10.1001/archpediatrics.2012.164 – volume: 151 start-page: 2423 year: 2010 ident: 577_CR110 publication-title: Endocrinology doi: 10.1210/en.2010-0089 – volume: 170 start-page: 5382 year: 2003 ident: 577_CR13 publication-title: J Immunol doi: 10.4049/jimmunol.170.11.5382 – volume: 96 start-page: e7024 year: 2017 ident: 577_CR132 publication-title: Medicine doi: 10.1097/MD.0000000000007024 – volume: 56 start-page: 2616 year: 2007 ident: 577_CR93 publication-title: Diabetes doi: 10.2337/db07-0652 – volume: 8 start-page: 1 year: 2017 ident: 577_CR37 publication-title: Front Immunol – volume: 31 start-page: 3653 year: 2011 ident: 577_CR55 publication-title: Mol Cell Biol doi: 10.1128/MCB.05020-11 – volume: 187 start-page: 1 year: 2018 ident: 577_CR128 publication-title: J Steroid Biochem Mol Biol doi: 10.1016/j.jsbmb.2018.10.008 – volume: 88 start-page: 50 year: 2018 ident: 577_CR153 publication-title: J Autoimmun doi: 10.1016/j.jaut.2017.10.001 – volume: 17 start-page: 6 year: 2008 ident: 577_CR8 publication-title: Lupus doi: 10.1177/0961203307085879 – volume: 15 start-page: 352 year: 2013 ident: 577_CR149 publication-title: Curr Rheumatol Rep doi: 10.1007/s11926-013-0352-0 – volume: 54 start-page: 944 year: 1995 ident: 577_CR123 publication-title: Ann Rheum Dis doi: 10.1136/ard.54.12.944 – volume: 107 start-page: 14751 year: 2010 ident: 577_CR140 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1003852107 – volume: 32 start-page: 863 year: 2013 ident: 577_CR118 publication-title: Clin Rheumatol doi: 10.1007/s10067-013-2174-x – volume: 159 start-page: 967 year: 2018 ident: 577_CR30 publication-title: Endocrinology doi: 10.1210/en.2017-00748 – volume: 285 start-page: 2227 year: 2010 ident: 577_CR31 publication-title: J Biol Chem doi: 10.1074/jbc.C109.071225 – volume: 4 start-page: e5810 year: 2009 ident: 577_CR34 publication-title: PLoS ONE doi: 10.1371/journal.pone.0005810 – volume: 10 start-page: e0131539 year: 2015 ident: 577_CR136 publication-title: PLoS ONE doi: 10.1371/journal.pone.0131539 – volume: 82 start-page: 1300 year: 1993 ident: 577_CR14 publication-title: Blood doi: 10.1182/blood.V82.4.1300.1300 – volume: 60 start-page: 1624 year: 2011 ident: 577_CR94 publication-title: Diabetes doi: 10.2337/db10-1656 – volume: 16 start-page: 53 year: 2015 ident: 577_CR120 publication-title: BMC Musculoskelet Disord doi: 10.1186/s12891-015-0505-6 – volume: 105 start-page: 5207 year: 2008 ident: 577_CR62 publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0711558105 – volume: 164 start-page: 2405 year: 2000 ident: 577_CR47 publication-title: J Immunol doi: 10.4049/jimmunol.164.5.2405 – volume: 39 start-page: 423 year: 2017 ident: 577_CR116 publication-title: Semin Immunopathol doi: 10.1007/s00281-017-0620-6 – volume: 365 start-page: 410 year: 2011 ident: 577_CR23 publication-title: N Engl J Med doi: 10.1056/NEJMoa1103864 – volume: 16 start-page: R97 year: 2014 ident: 577_CR150 publication-title: Arthritis Res Ther doi: 10.1186/ar4545 – volume: 311 start-page: 1770 year: 2006 ident: 577_CR33 publication-title: Science doi: 10.1126/science.1123933 – volume: 157 start-page: 48 year: 2009 ident: 577_CR43 publication-title: Clin Exp Immunol doi: 10.1111/j.1365-2249.2009.03961.x – volume: 195 start-page: 603 year: 2002 ident: 577_CR58 publication-title: J Exp Med doi: 10.1084/jem.20011629 – volume: 189 start-page: 5155 year: 2012 ident: 577_CR15 publication-title: J Immunol doi: 10.4049/jimmunol.1200786 – volume: 62 start-page: 3656 year: 2010 ident: 577_CR142 publication-title: Arthritis Rheum doi: 10.1002/art.27756 – volume: 149 start-page: 4799 year: 2008 ident: 577_CR109 publication-title: Endocrinology doi: 10.1210/en.2008-0060 – volume: 25 start-page: 564 year: 2014 ident: 577_CR32 publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2013040355 – volume: 11 start-page: 344 year: 2010 ident: 577_CR60 publication-title: Nat Immunol doi: 10.1038/ni.1851 – volume: 27 start-page: 199 year: 2018 ident: 577_CR84 publication-title: Lupus doi: 10.1177/0961203317716321 – volume: 321 start-page: 103 year: 2010 ident: 577_CR18 publication-title: Mol Cell Endocrinol doi: 10.1016/j.mce.2010.02.013 – volume: 2013 start-page: 160123 year: 2013 ident: 577_CR157 publication-title: Clin Dev Immunol doi: 10.1155/2013/160123 – volume: 180 start-page: 2786 year: 2008 ident: 577_CR66 publication-title: J Immunol doi: 10.4049/jimmunol.180.5.2786 – volume: 67 start-page: 530 year: 2008 ident: 577_CR88 publication-title: Ann Rheum Dis doi: 10.1136/ard.2007.072736 – volume: 62 start-page: A172 year: 2013 ident: 577_CR107 publication-title: Gut doi: 10.1136/gutjnl-2013-304907.038 – volume: 156 start-page: 2674 year: 1996 ident: 577_CR56 publication-title: J Immunol doi: 10.4049/jimmunol.156.8.2674 – volume: 523 start-page: 103 year: 2012 ident: 577_CR7 publication-title: Arch Biochem Biophys doi: 10.1016/j.abb.2011.11.001 – volume: 86 start-page: 23 year: 2011 ident: 577_CR25 publication-title: Vitam Horm doi: 10.1016/B978-0-12-386960-9.00002-2 – volume: 32 start-page: 1081 year: 2013 ident: 577_CR121 publication-title: Clin Rheumatol doi: 10.1007/s10067-013-2216-4 – volume: 13 start-page: 712 year: 2013 ident: 577_CR138 publication-title: Curr Top Med Chem doi: 10.2174/1568026611313060004 – volume: 29 start-page: 726 year: 2008 ident: 577_CR28 publication-title: Endocr Rev doi: 10.1210/er.2008-0004 – volume: 71 start-page: 606 year: 2012 ident: 577_CR156 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2011-200424 – volume: 12 start-page: 201 year: 2016 ident: 577_CR9 publication-title: Nat Rev Rheumatol doi: 10.1038/nrrheum.2015.140 – volume: 9 start-page: e109194 year: 2014 ident: 577_CR152 publication-title: PLoS ONE doi: 10.1371/journal.pone.0109194 – volume: 64 start-page: 7 year: 2018 ident: 577_CR82 publication-title: Cell Mol Biol doi: 10.14715/cmb/2018.64.1.2 – volume: 7 start-page: e407 year: 2013 ident: 577_CR106 publication-title: J Crohn’s Colitis doi: 10.1016/j.crohns.2013.01.012 – volume: 68 start-page: 91 year: 2016 ident: 577_CR89 publication-title: Arthritis Care Res (Hoboken) doi: 10.1002/acr.22621 – volume: 16 start-page: 261 year: 2005 ident: 577_CR91 publication-title: Trends Endocrinol Metab doi: 10.1016/j.tem.2005.06.004 – volume: 23 start-page: 233 year: 2004 ident: 577_CR42 publication-title: J Autoimmun doi: 10.1016/j.jaut.2004.06.004 – volume: 303 start-page: 1815 year: 2010 ident: 577_CR160 publication-title: JAMA doi: 10.1001/jama.2010.594 – volume: 7 start-page: 337 year: 2011 ident: 577_CR26 publication-title: Nat Rev – volume: 12 start-page: 513 year: 2016 ident: 577_CR104 publication-title: Gastroenterol Hepatol – volume: 38 start-page: 2210 year: 2008 ident: 577_CR65 publication-title: Eur J Immunol doi: 10.1002/eji.200838216 – volume: 73 start-page: 2047 year: 2014 ident: 577_CR145 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-203566 – volume: 71 start-page: 50 year: 2012 ident: 577_CR52 publication-title: Proc Nutr Soc doi: 10.1017/S0029665111001650 – volume: 84 start-page: 3739 year: 1999 ident: 577_CR45 publication-title: J Clin Endocrinol Metab – volume: 182 start-page: 2074 year: 2009 ident: 577_CR49 publication-title: J Immunol (Baltimore, Md.: 1950) doi: 10.4049/jimmunol.0803345 – volume: 74 start-page: 1293 year: 2015 ident: 577_CR148 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-204228 |
| SSID | ssj0014666 |
| Score | 2.6067944 |
| SecondaryResourceType | review_article |
| Snippet | Vitamin D has been reported to influence physiological systems that extend far beyond its established functions in calcium and bone homeostasis. Prominent... |
| SourceID | pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 58 |
| SubjectTerms | Antigen-presenting cells Arthritis, Rheumatoid - immunology Arthritis, Rheumatoid - metabolism Autoimmune diseases Autoimmune Diseases - immunology Autoimmune Diseases - metabolism Biochemistry Biomedical and Life Sciences Bone and Bones - immunology Bone and Bones - metabolism Bone turnover Calcitriol Calcium homeostasis CD4 antigen Cell Biology Endocrinology Helper cells Homeostasis Humans Hydroxylase Immunomodulation Immunomodulators Immunoregulation Inflammation Life Sciences Lymphocytes T Microenvironments Nutrient deficiency Orthopedics Phenotypes Receptors, Calcitriol - genetics Review Reviews Rheumatoid arthritis Supplements Vitamin D Vitamin D - metabolism Vitamin D - pharmacokinetics Vitamin D - pharmacology Vitamin D Deficiency - immunology Vitamin D Deficiency - prevention & control Vitamin D receptors Vitamin D3 Vitamin deficiency |
| SummonAdditionalLinks | – databaseName: Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwEB5BkRAXBC2PQEFGQlyoBbEdOzmhFaWqkOCAKNpbFL-0kWhS6O6Bf8-M4021VPQY2Xl4xrG_efgbgNcUKoulKHnpreLKdoHbhooIyFJXQdXWuZQg-1WfnqnPy2qZHW6XOa1yuyamhdqPjnzk73DeSa2I2uXDxS9OVaMouppLaNyGO0RdRildZjkbXLgITLHK0pS80WaZD82ko3O0eVEmUcPpPKbhYndjuoY2rydN_hM5TRvSyQO4n5EkW0yqfwi3wrAPB4sBrejzP-wNS7mdyWm-D3e_5BD6Aegf_bo77wd2fMQWm_XY0wGRwI6nQA3rBs--rcIGgezYe3r6KtEePYKzk0_fP57yXDyBOwRhVGI-Gi-U1T7GWDfvEQd5WQdfd8JEIQPaMXiNaMsZ2WhrKluX2lVOOYIsVsjHsDeMQ3gKDJUXtNO-Ub5WkRxXdVQiGiN1ZXwXCyi3kmtdZhanAhc_25kTOUm7RWm3SdqtKODtfM_FxKtxY-_DrULa_I9dtlczooBXczP-HRTy6IYwblIf4s9RWhXwZNLf_DqJWzPiN2wxO5qdOxDz9m7L0K8SA7dGu09IXcDRdg5cfdb_R_Hs5lE8h3uCjPnk3zmEvfXvTXiBiGdtX6Zp_Rccuvkn priority: 102 providerName: ProQuest |
| Title | Vitamin D, Autoimmune Disease and Rheumatoid Arthritis |
| URI | https://link.springer.com/article/10.1007/s00223-019-00577-2 https://www.ncbi.nlm.nih.gov/pubmed/31286174 https://www.proquest.com/docview/2253641691 https://www.proquest.com/docview/2254519464 https://pubmed.ncbi.nlm.nih.gov/PMC6960236 |
| Volume | 106 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1ba9RAFD5oC-KLaOsltV1GEF9swMxMZpLH7HbXorhIcWV9CpkbG7BZaXcf-u97ZnIpa1XwKYQ5mSTnzOU7c24Ab72pzCU0iROjeMxVZWOV-yICLBGp5ZnSOjjIzsX5gn9apssuKOy693bvTZJhpR6C3fx2431_8thHUMoYF9791OvuOIoXtBhsB1y0FspEJnEu5LILlflzH7vb0T2Med9V8jd7adiGZk_hSYcfSdEK_Bk8sM0BHBYN6s6XN-QdCR6d4aj8AB596QznhyC-15vqsm7I2Skptpt17cNCLDlrzTOkagy5WNktwtd1bXzvq5Ds6DksZtNvk_O4K5kQa4RevrC8k4ZyJYxzLss_IPoxLLMmq6h0lFnUXvAeMZaWLBdKpipLhE411x6oKMpewF6zbuwrICgyK7QwOTcZd_64KnOcOimZSKWpXARJz7lSd_nEfVmLn-WQCTlwu0Rul4HbJY3g_fDMrzabxj-pj3uBlN3Mui5x_WGC-xQ_EbwZmnFOeENH1dj1NtD4rDlc8AhetvIbXsdwQ0bUhi1yR7IDgc-3vdvS1KuQd1ugtkeZiOC0HwN3n_X3vzj6P_LX8Jh6lT6c8hzD3uZqa08Q92zUCB7KpRzBfjEbj-f--vHH5ylex9P51wtsnYjJKEyFW_LI_HQ |
| linkProvider | Springer Nature |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB5VWwm4IGh5BAoYCbjQCOI4dnJAaGFbbWm7QlWL9hYSP7SRaLbQXaH-KX4jM86jWip66zGy8xqP7c_z-AbgFbnKXMSjMDKlCEVZ2LDMqIhAHMnEirTU2gfITuT4RHyZJtM1-NPlwlBYZbcm-oXazDXZyN-h3sVSELXLx7OfIVWNIu9qV0KjUYt9e_Ebj2znH_ZGOL6vOd_dOf48DtuqAqFGdEK1150yXJTSOOfS7D0CBBOn1qQFV47HFgE-XiMM0SrOZKmSMo2kTrTQtJeXRHSAS_66iPEoM4D1TzuTr0e930LIxjsaqSjMpJq2aTo-WY-2S4pdykLKAFUhX90Kr-Dbq2Ga__hq_Ra4ew_uttiVDRtluw9rtt6AzWGN5_bTC_aG-WhSb6bfgFuHrdN-E-S3alGcVjUbbbPhcjGvKCXFslHjGmJFbdjRzC4ROs8rQ0-feaKlB3ByI4J9CIN6XtvHwFBdrNTSZMKkwpGpLHWCO6VimShTuACiTnK5brnMqaTGj7xnYfbSzlHauZd2zgN4299z1jB5XNt7qxuQvJ3V5_mlDgbwsm_G-UhOlqK286XvQ4w9QooAHjXj178uRjCAiBFb1MrI9h2I63u1pa5mnvNb4kmTxzKA7U4HLj_r_3_x5Pq_eAG3x8eHB_nB3mT_KdzhZErw1qUtGCx-Le0zxFuL8nmr5Ay-3_S8-gvm3DY3 |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB5VRaq4INryCC3FSMCFRiWOYycHVK1YVi2FCiGK9hYSP7SRaNLHrlD_Gr-OGedRLRW99biys7sZz9if5_ENwCsKlbmIR2FkShGKsrBhmVETgTiSiRVpqbVPkD2WByfi0zSZrsCfvhaG0ir7PdFv1KbR5CPfQ72LpSBqlz3XpUV8HU_2z85D6iBFkda-nUarIkf26jde3y7fH45xrV9zPvn4_cNB2HUYCDUiFerD7pThopTGOZdm7xAsmDi1Ji24cjy2CPbxM0ISreJMliop00jqRAtN53pJpAe4_d9TcRKRjanpcNnDDaiNk0YqCjOppl3Bji_bo4OTspiykGpBVciXD8UbSPdmwuY_UVt_GE4ewoMOxbJRq3brsGLrDdgc1XiDP71ib5jPK_UO-w1Y-9KF7zdB_qjmxWlVs_EuGy3mTUXFKZaN2yARK2rDvs3sAkF0Uxn69pmnXHoEJ3ci1sewWje1fQoMFcdKLU0mTCocOc1SJ7hTKpaJMoULIOoll-uO1Zyaa_zKBz5mL-0cpZ17aec8gLfDM2ctp8ets7f7Bck7-77Mr7UxgJfDMFomhVuK2jYLP4e4e4QUATxp12_4uRhhAWJHHFFLKztMINbv5ZG6mnn2b4l3Th7LAHZ7Hbj-W_9_i2e3v8ULWENryj8fHh9twX1OPgXvZtqG1fnFwj5H4DUvd7yGM_h51yb1F0GROQc |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Vitamin+D%2C+Autoimmune+Disease+and+Rheumatoid+Arthritis&rft.jtitle=Calcified+tissue+international&rft.au=Harrison%2C+Stephanie+R&rft.au=Li%2C+Danyang&rft.au=Jeffery%2C+Louisa+E&rft.au=Raza%2C+Karim&rft.date=2020-01-01&rft.issn=1432-0827&rft.eissn=1432-0827&rft.volume=106&rft.issue=1&rft.spage=58&rft_id=info:doi/10.1007%2Fs00223-019-00577-2&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0171-967X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0171-967X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0171-967X&client=summon |