Role of androgen receptor signaling pathway-related lncRNAs in the prognosis and immune infiltration of breast cancer

• Published in: Scientific reports Vol. 12; no. 1; pp. 20631 - 17
• Main Authors: Huang, Guo, Cao, Hong, Liu, Guowen, Chen, Juan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 30.11.2022; Nature Publishing Group; Nature Portfolio
• Subjects: 692/4028; 692/499; Androgen receptors; Androgens; Breast cancer; Breast Neoplasms - genetics; CD4 antigen; Cluster analysis; Female; Gene set enrichment analysis; Humanities and Social Sciences; Humans; Immunosuppressive agents; Infiltration; Lymphocytes B; Lymphocytes T; Macrophages; Metastases; multidisciplinary; Nomograms; Non-coding RNA; Prognosis; Receptors, Androgen - genetics; Regression analysis; Risk groups; RNA, Long Noncoding - genetics; Science; Science (multidisciplinary); Signal Transduction; Tumor microenvironment; Tumor Microenvironment - genetics; Tumors

Androgen receptor (AR) is strong association with breast cancer (BRCA). We aimed to investigate the effect of the androgen receptor signaling pathway-related long non-coding RNAs (ARSP-related lncRNAs) on the process of subtype classification and the tumor microenvironment (TME) of breast cancer (BR...