A novel methodology for 3D deformable dosimetry

• Published in: Medical physics (Lancaster) Vol. 39; no. 4; pp. 2203 - 2213
• Main Authors: Yeo, U. J., Taylor, M. L., Dunn, L., Kron, T., Smith, R. L., Franich, R. D.
• Format: Journal Article
• Language: English
• Published: United States American Association of Physicists in Medicine 01.04.2012
• Subjects: 3D gel dosimetry; ALGORITHMS; aluminium; Anatomy; biological organs; biomechanics; Calibration; CAT SCANNING; COMPRESSORS; Computed tomography; Computerised tomographs; computerised tomography; DEFORMATION; DELIVERY; Digital computing or data processing equipment or methods, specially adapted for specific applications; DISTRIBUTION; dose deformation; DOSEMETERS; dosimeters; dosimetry; Dosimetry/exposure assessment; Elastic Modulus; Electrical, thermal, and mechanical properties of biological matter; GELS; Gels - chemistry; Gels - radiation effects; HEALTH HAZARDS; IRRADIATION; Materials Testing; Mechanical and electrical properties of tissues and organs; medical computing; Medical imaging; MEMBRANES; optical CT; organ deformation; PHANTOMS; polymer gels; Polymers; Quantum dots; Radiation Dosage; RADIATION DOSE DISTRIBUTIONS; RADIATION DOSES; RADIATION PROTECTION AND DOSIMETRY; radiation therapy; RADIOLOGY AND NUCLEAR MEDICINE; Radiometry - instrumentation; RADIOTHERAPY; READOUT SYSTEMS; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed - methods; VERIFICATION; organ deformation; dose deformation; optical CT; 3D gel dosimetry

Purpose: Interfraction and intrafraction variation in anatomic structures is a significant challenge in contemporary radiotherapy. The objective of this work is to develop a novel tool for deformable structure dosimetry, using a tissue-equivalent deformable gel dosimeter that can reproducibly simula...