Fatty Acid Ethyl Esters in Meconium: Are They Biomarkers of Fetal Alcohol Exposure and Effect?

• Published in: Alcoholism, clinical and experimental research Vol. 30; no. 7; pp. 1152 - 1159
• Main Authors: Ostrea Jr, Enrique M., Hernandez, Joel D., Bielawski, Dawn M., Kan, Jack M., Leonardo, Gregorio M., Abela, Michelle Buda, Church, Michael W., Hannigan, John H., Janisse, James J., Ager, Joel W., Sokol, Robert J.
• Format: Journal Article
• Language: English
• Published: Malden, USA Blackwell Publishing Inc 01.07.2006; Lippincott Williams & Wilkins
• Subjects: Adult; Alcohol Drinking - metabolism; Alcoholism and acute alcohol poisoning; Arachidonic Acids - metabolism; Biological and medical sciences; Biomarkers - metabolism; Esters - metabolism; Ethanol - pharmacology; Ethyl Arachidonate; Ethyl Docosahexanoate; Ethyl Laurate; Ethyl Linoleate; Ethyl Linolenate; Ethyl Myristate; Ethyl Oleate; Ethyl Palmitate; Fatty Acid Ethyl Esters; Fatty Acids - metabolism; Female; Fetal Alcohol Syndrome; Fetus - drug effects; Gas Chromatography/Mass Spectroscopy; Humans; Infant, Newborn; Maternal Alcoholism; Meconium - metabolism; Medical sciences; Pregnancy; Toxicology; Fetal alcohol syndrome; Ethyl Linolenate; Maternal Alcoholism; Biological marker; Lipids; Alcoholic beverage; Ester; Gas Chromatography/Mass Spectroscopy; Mother; Fetus; Ethyl Docosahexanoate; Ethanol; Ethyl Linoleate; Fatty Acid Ethyl Esters; Ethyl Myristate; Alcoholism; Exposure; Fatty acids; Gas chromatography; Newborn diseases; Ethyl Palmitate; Ethyl Laurate; Meconium; Ethyl Oleate; Ethyl Arachidonate; Mass spectrometry

Background: Biomarkers of fetal exposure to alcohol are important to establish so that early detection and intervention can be made on these infants to prevent undesirable outcomes. The aim of this study was to analyze long‐chain fatty acid ethyl esters (FAEEs) in meconium as potential biomarkers of...