Agarwood Oil Nanoemulsion Attenuates Cigarette Smoke-Induced Inflammation and Oxidative Stress Markers in BCi-NS1.1 Airway Epithelial Cells

• Published in: Nutrients Vol. 15; no. 4; p. 1019
• Main Authors: De Rubis, Gabriele, Paudel, Keshav Raj, Manandhar, Bikash, Singh, Sachin Kumar, Gupta, Gaurav, Malik, Raniya, Shen, Jessie, Chami, Aniss, MacLoughlin, Ronan, Chellappan, Dinesh Kumar, Oliver, Brian Gregory George, Hansbro, Philip Michael, Dua, Kamal
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.02.2023; MDPI
• Subjects: 1-Phosphatidylinositol 3-kinase; agarwood; Anti-Inflammatory Agents - pharmacology; Antioxidants; Antioxidants - pharmacology; Care and treatment; Chemical properties; Chronic obstructive pulmonary disease; Cigarette smoke; Cigarette Smoking; Cigarettes; Cough; Cytokines; Detoxification; Development and progression; Dilleniidae; Drug delivery; Drug delivery systems; Enzymes; Epithelial Cells; Epithelium; Essences and essential oils; Essential oils; Gene expression; Glutathione transferase; Health aspects; Health services; Inflammation; Inflammation - metabolism; Inflammatory diseases; Interleukin 10; Interleukin 8; Lung diseases; Lung diseases, Obstructive; nanoemulsion; Nanoemulsions; Nanoparticles; Nicotiana; nutraceuticals; Obstructive lung disease; Oils & fats; Oxidants; Oxidative Stress; Oxidizing agents; Pharmacokinetics; Physiological aspects; phytoceuticals; Plant extracts; Platelet-derived growth factor; Proteins; Pulmonary Disease, Chronic Obstructive - metabolism; Relaxin; Respiratory diseases; Respiratory tract; Risk factors; Signal transduction; Signs and symptoms; Smoke; Smoking; Tumor necrosis factor-TNF; γ-Interferon; Australia; phytoceuticals; inflammation; nutraceuticals; drug delivery; agarwood; cigarette smoke; nanoemulsion; chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is an irreversible inflammatory respiratory disease characterized by frequent exacerbations and symptoms such as cough and wheezing that lead to irreversible airway damage and hyperresponsiveness. The primary risk factor for COPD is chronic cigarette smok...