Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway - Cheng, Bisheng; Li, Lingfeng; Luo, Tianlong; Wang, Qiong; Luo, Yong; Bai, Shoumin; Li, Kaiwen; Lai, Yiming; Huang, Hai (Journal of experimental & clinical cancer research, 2024)
Keywords: Algorithms; Antibodies; Autocrine signalling; Binding proteins; Cancer; Cancer therapies; Care and treatment; Cell cycle; Cell growth; Chemotherapy; Chromatin; Cytokines; Docetaxel - pharmacology; Docetaxel resistance; Drug Resistance, Neoplasm - genetics; Gene Expression Regulation; Health aspects; Humans; IL-11; Interleukin-11 - genetics; Interleukin-11 - metabolism; Interleukins; Janus Kinase 1 - genetics; Janus Kinase 1 - metabolism; Kinases; Male; Metastasis; Prostate cancer; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - genetics; Prostatic Neoplasms - metabolism; Protein binding; Proteins; Signal Transduction; Single-cell analysis; STAT4 Transcription Factor - metabolism; China; Beijing China; United States--US; Japan; Autocrine signalling; Docetaxel resistance; Single-cell analysis; IL-11; Prostate cancer